LC-MS determination of urinary toluenediamine in workers exposed to toluenediisocyanate

Toxicology Letters

Volumn 134, Issue 1-3, 2002, Pages 259-264

  Sakai, Tadashi ^a   Morita, Y ^a   Kim, Y ^b   Tao, Y X ^c  

^a TOKYO ROSAI HOSPITAL   (Japan)

^b Ulsan University College of Medicine   (South Korea)

^c Beijing Inst Labor Hyg/Occup Dis   (China)

Author keywords

Biological monitoring; Liquid chromatography mass spectrometry; Toluenediamine; Toluenediisocyanate; Urine

Indexed keywords

2,4 DIAMINOTOLUENE; 2,6 DIAMINOTOLUENE; DICHLOROMETHANE; SULFURIC ACID; TOLUENE DIISOCYANATE;

ALKALINIZATION; ANALYTIC METHOD; BIOLOGICAL MONITORING; CALIBRATION; CONFERENCE PAPER; CONTROLLED STUDY; CORRELATION ANALYSIS; HUMAN; HYDROLYSIS; ISOMER; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITE; OCCUPATIONAL EXPOSURE; OCCUPATIONAL HAZARD; PRIORITY JOURNAL; PROTON TRANSPORT; URINALYSIS; URINE LEVEL;

CHROMATOGRAPHY, LIQUID; ENVIRONMENTAL MONITORING; HUMANS; INHALATION EXPOSURE; MASS SPECTROMETRY; OCCUPATIONAL EXPOSURE; PHENYLENEDIAMINES; TOLUENE 2,4-DIISOCYANATE;

EID: 0037025557     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(02)00174-1     Document Type: Conference Paper

References (18)

1. Isocyanate-induced respiratory disease
2. Respiratory and other hazards of isocyanates
3. Biological monitoring of isocyanates and related amines. IV. 2,4- and 2,6-toluenediamine in hydrolyzed plasma and urine after test-chamber exposure of humans to 2,4- and 2,6-toluene diisocyanate
4. Allergic contact dermatitis to a photopolymerizable resin used in printing
5. Clinical features and epidemiology of occupational obstructive respiratory disease caused by small molecular weight organic chemicals
6. Toxicokinetics of 2,4- and 2,6-toluenediamine in hydrolysed urine and plasma after occupational exposure to 2,4- and 2,6- toluene diisocyanate
7. Biomarkers in hydrolyzed urine, plasma and erythrocytes among workers exposed to thermal degradation products from toluene diisocyanate foam
8. Toxic corneal epithelial edema from exposure to high atmospheric concentration of toluene diisocyanatez
9. Biological monitoring of occupational exposure to toluene diisocyanate
10. Determination of urinary metabolites of toluenediisocyanate, using GC-MS
11. Four-year follow-up of effects of toluene diisocyanate exposure on the respiratory system in polyurethane foam manufacturing workers. II. Four-year changes in the effects on the respiratory system
12. Biological monitoring of occupational exposure to toluene diisocyanate: Measurement of toluenediamine in hydrolysed urine and plasma by gas chromatography-mass spectrometry
13. Chromatographic determination of amines in biological fluids with special reference to the biological monitoring of isocyanates and amines. II. Determination of 2,4- and 2,6-toluenediamine using glass capillary gas chromatography and selected ion monitoring
14. Biological monitoring of isocyanates and related amines. III. Test chamber exposure of humans to toluene diisocyanate
15. Liquid chromatography and mass spectrometry determination of aromatic amines in hydrolysed urine from workers exposed to thermal degradation products of polyurethane
16. Determination of toluenediamine isomers by capillary gas chromatography and chemical ionization mass spectrometry with special reference to the biological monitoring of 2,4- and 2 6-toluene diisocyanate
17. Air and biological monitoring of toluene diisocyanate in a flexible foam plant