Structure-activity relationships of non-imidazole H3 receptor ligands. Part 2: Binding preference for D-amino acids motifs

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 15, 2002, Pages 2035-2037

  Faghih, Ramin ^a   Dwight, Wesley ^a   Black, Larry ^a   Liu, Huaqing ^a   Gentles, Robert ^a   Phelan, Kathleen ^a   Esbenshade, Timothy A ^a   Ireland, Lynne ^a   Miller, Thomas R ^a   Kang, Chae Hee ^a   Krueger, Kathy M ^a   Fox, Gerard B ^a   Hancock, Arthur A ^a   Bennani, Youssef L ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 1 [4 [3 (4 CYCLOPROPANECARBONYLPHENOXY)PROPYL] 1 PIPERAZINYL] 1 PROPANONE; DEXTRO AMINO ACID; HISTAMINE H3 RECEPTOR; LIGAND; PIPERAZINE DERIVATIVE; UNCLASSIFIED DRUG; AMINO ACID; ANTIHISTAMINIC AGENT; HISTAMINE H1 RECEPTOR; HISTAMINE H2 RECEPTOR;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; HUMAN; LIGAND BINDING; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION; ACYLATION; ANIMAL; BINDING COMPETITION; BIOAVAILABILITY; BRAIN CORTEX; CHEMISTRY; DRUG EFFECT; KINETICS; METABOLISM; PROTEIN MOTIF;

ACYLATION; AMINO ACID MOTIFS; AMINO ACIDS; ANIMAL; BINDING, COMPETITIVE; BIOLOGICAL AVAILABILITY; CEREBRAL CORTEX; HISTAMINE ANTAGONISTS; HUMAN; KINETICS; LIGANDS; PIPERAZINES; RATS; RECEPTORS, HISTAMINE H1; RECEPTORS, HISTAMINE H2; RECEPTORS, HISTAMINE H3; STRUCTURE-ACTIVITY RELATIONSHIP; ANIMALS; HUMANS;

EID: 0037025466     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00310-4     Document Type: Article

References (15)