Regulated secretion in chromaffin cells: An essential role for ARF6-regulated phospholipase D in the late stages of exocytosis

Annals of the New York Academy of Sciences

Volumn 971, Issue , 2002, Pages 193-200

  Vitale, Nicolas ^a   Chasserot Golaz, Sylvette ^a   Bader, Marie France ^a  

^a CNRS   (France)

Author keywords

ARF; ARNO; Chromaffin; Exocytosis; Phospholipase D; Secretory granule

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR 6; ARF PROTEIN; CALCIUM ION; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; PHOSPHOLIPASE D; PROTEIN ARNO; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; AMPEROMETRY; ANIMAL CELL; ANTIBODY DETECTION; BINDING SITE; CALCIUM TRANSPORT; CATECHOLAMINE RELEASE; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CELL SECRETION; CELL STIMULATION; CHROMAFFIN CELL; CONFERENCE PAPER; ENZYME ACTIVATION; ENZYME REGULATION; EXOCYTOSIS; LIPID ANALYSIS; NEUROSECRETORY CELL; NONHUMAN; PEPTIDE SYNTHESIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; PROTEIN TRANSPORT; SECRETORY GRANULE;

ANIMALIA;

EID: 0037024607     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2002.tb04463.x     Document Type: Conference Paper

References (23)

1. Sollner, T., S.W. Whiteheart, M. Brunner, et al. 1993. SNAP receptors implicated in vesicle targeting and fusion. Nature 362: 318-324.
2. Rothman, J.E. 1994. Mechanisms of intracellular protein transport. Nature 372: 55-63.
3. Toutant, M., D. Aunis, J. Bockaert, et al. 1987. Presence of three pertussis toxin substrates and Go alpha immunoreactivity in both plasma and granule membranes of chromaffin cells. FEBS Lett. 215: 339-344.
4. Burgoyne, R.D. & A. Morgan. 1989. Low molecular mass GTP-binding proteins of adrenal chromaffin cells are present on the secretory granule. FEBS Lett. 247: 127-131.
5. Doucet, J.P., S. Fournier, M. Parulekar & J.M. Trifaro. 1989. Detection of low molecular mass GTP-binding proteins in chromaffin granules and other subcellular fractions of chromaffin cells. FEBS Lett. 247: 127-131.
6. Darchen, F., A. Zahraoui, F. Hammel, et al. 1990. Association of the GTP-binding protein Rab3A with bovine adrenal chromaffin granules. Proc. Natl. Acad. Sci. USA 87: 5692-5696.
7. 3 bound to the plasma membrane. Eur. J. Neurosci. 8: 1275-1285.
8. Ahnert-Hilger, G., T. Schafer, K. Spicher, et al. 1994. Detection of G-protein heterotrimers on large dense core and small synaptic vesicles of neuroendocrine and neuronal cells. Eur. J. Cell Biol. 65: 26-38.
9. Galas, M.C., J.B. Helms, N. Vitale, et al. 1997. Regulated exocytosis in chromaffin cells. A potential role for a secretory granule-associated ARF6 protein. J. Biol. Chem. 272: 2788-2793.
10. Donaldson, J.G. & R.D. Klausner. 1994. ARF: A key regulatory switch in membrane traffic and organelle structure. Curr. Opin. Cell Biol. 4: 527-532.
11. Amor, J.C., D.H. Harrison, R.A. Kahn & D. Ringe. 1994. Structure of the human ADP-ribosylation factor 1 complexed with GDP. Nature 372: 704-708.
12. 2+ levels. J. Biol. Chem. 270: 1337-1341.
13. Moss, J. & M. Vaughan. 1995. Structure and function of ARF proteins: Activators of cholera toxin and critical components of intracellular vesicular transport processes. J. Biol. Chem. 270: 12327-12330.
14. Caumont, A.S., M.C. Galas, N. Vitale, et al. 1998. Regulated exocytosis in chromaffin cells. Translocation of ARF6 stimulates a plasma membrane-associated phospholipase D. J. Biol. Chem. 273: 1373-1379.
15. Caumont, A.S., N. Vitale, M. Gensse, et al. 2000. Identification of a plasma membrane-associated guanine nucleotide exchange factor for ARF6 in chromaffin cells. Possible role in the regulated exocytotic pathway. J. Biol. Chem. 275: 15637-15644.
16. Brown, H.A., S. Gutowski, C.R. Moomaw, et al. 1993. ADP-ribosylation factor, a small GTP-dependent regulatory protein, stimulates phospholipase D activity. Cell 75: 1137-1144.
17. Kahn, R.A., J.K. Yucel & V. Malhotra. 1993. ARF signaling: A potential role for phospholipase D in membrane traffic. Cell 75: 1045-1048.
18. Vitale, N., A.S. Caumont, S. Chasserot-Golaz, et al. 2001. Phospholipase D1: A key factor for the exocytotic machinery in neuroendocrine cells. EMBO J. 20: 2424-2434.
19. Graham, M.E. & R.D. Burgoyne. 2000. Comparison of cystein string protein (Csp) and mutant a-SNAP overexpression reveals a role for Csp in late steps of membrane fusion in dense core granule exocytosis in adrenal chromaffin cells. J. Neurosci. 15: 1281-1289.
20. Hay, J.C., P.L. Fisette, G.H. Jenkins, et al. 1995. ATP-dependent inositide phosphorylation required for Ca(2+)-activated secretion. Nature 374: 173-177.
21. Monck, J.R. & J.M. Fernandez. 1994. The exocytotic fusion pore and neurotransmitter release. Neuron 12: 707-716.
22. Siegel, D.P. 1999. The modified stalk mechanism of lamellar/inverted phase transitions and its possible implications for membrane fusion. Biophys. J. 76: 291-313.
23. Weigert, R., M.G. Silleta, S. Spano, et al. 1999. CtBP/BARS induces fission of Golgi membranes by acylating lysophosphatidic acid. Nature 402: 429-433.