Role of N-acetylglutamate concentration and ornithine transport into mitochondria in urea synthesis of rats given proteins of different quality

Journal of Agricultural and Food Chemistry

Volumn 50, Issue 25, 2002, Pages 7467-7471

  Tujioka, Kazuyo ^a   Lyou, Sunok ^a   Hirano, Emi ^a   Sano, Atushi ^a   Hayase, Kazutoshi ^a   Yoshida, Akira ^b   Yokogoshi, Hidehiko ^c  

^a AICHI UNIVERSITY OF EDUCATION   (Japan)

^b Nagoya Bunri College   (Japan)

^c UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

Dietary protein quality; N acetylglutamate; Ornithine transport; Rats; Urea synthesis

Indexed keywords

CASEIN; EGG PROTEIN; GLUTAMIC ACID; GLUTAMIC ACID DERIVATIVE; GLUTEN; LYSINE; N ACETYLGLUTAMIC ACID; N-ACETYLGLUTAMATE; ORNITHINE; UREA;

ANIMAL; ARTICLE; BLOOD; CONTROLLED STUDY; FOOD COMPOSITION; FOOD QUALITY; LIVER; LIVER LEVEL; LIVER MITOCHONDRION; MALE; METABOLISM; MITOCHONDRION; NONHUMAN; PROTEIN INTAKE; RAT; RAT STRAIN; SYNTHESIS; TRANSPORT AT THE CELLULAR LEVEL; UREA BLOOD LEVEL; UREA CYCLE; URINE LEVEL;

ANIMALS; BIOLOGICAL TRANSPORT; CASEINS; DIETARY PROTEINS; EGG PROTEINS; GLUTAMATES; GLUTEN; LIVER; MALE; MITOCHONDRIA, LIVER; ORNITHINE; RATS; RATS, WISTAR; UREA;

ANIMALIA;

EID: 0037021613     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf025635r     Document Type: Article

References (34)

1. Schimke, R. T. Adaptive characteristics of urea cycle enzymes in the rat. J. Biol. Chem. 1962, 237, 459-468.
2. Schimke, R. T. Studies on factors affecting the levels of urea cycle enzymes in rat livers. J. Biol. Chem. 1963, 238, 1012-1018.
3. Das, T. K.; Waterlow, J. C. The rate of adaptation of urea cycle enzymes in rat liver. Br. J. Nutr. 1974, 32, 353-373.
4. Kiriyama, S.; Iwao, H.; Ashida, K. Dietary protein quality and liver arginase activity of rats. Agric. Biol. Chem. 1967, 31, 671-674.
5. Hayase, K.; Yokogoshi, H.; Yoshida, A. Effect of dietary proteins and amino acid deficiencies on urinary excretion of nitrogen and the urea synthesizing system in rats. J. Nutr. 1980, 110, 1327-1337.
6. Greenstein, J. P.; Winitz, M.; Gullino, P.; Bilnbaum, S. M.; Otey, M. C. Studies on the metabolism of amino acids and related compounds in vivo. III. Prevention of ammonia toxicity by arginine and related compounds. Arch. Biochem. Biophys. 1956, 64, 342-354.
7. Kramer, J. W.; Freedland, R. A. Possible rate-limiting factors in urea synthesis by the perfused rat liver. Proc. Soc. Exp. Biol. Med. 1972, 141, 833-835.
8. Saheki, T.; Katunuma, N. Analysis of regulatory factors for urea synthesis by isolated perfused liver. I. Urea synthesis with ammonia and glutamine as nitrogen sources. J. Biochem. 1975, 77, 659-669.
9. Saheki, T.; Tsuda, M.; Tanaka, T.; Katunuma, N. Analysis of regulatory factors for urea synthesis by isolated perfused liver. II. Comparison of urea synthesis in livers of rats subjected to different dietary conditions. J. Biochem. 1975, 77, 671-678.
10. Briggs, S.; Freedland, R. A. Effect of ornithine and lactate on urea synthesis in isolated hepatocytes. Biochem. J. 1976, 160, 205-209.
11. Shigesada, K.; Tatibana, M. Role of acetylglutamate in ureoterism. I. Occurrence and biosynthesis of acetylglutamate in mouse and rat tissue. J. Biol. Chem. 1971, 246, 5588-5595.
12. Shigesada, K.; Tatibana, M. Enzymic synthesis of acetylglutamate by mammalian liver preparations and its stimulation by arginine. Biochem. Biophys. Res. Commun. 1971, 44, 1117-1124.
13. Shigesada, K.; Tatibana, M. N-Acetylglutamate synthetase from rat liver mitochondria. Eur. J. Biochem. 1978, 84, 285-291.
14. Cohen, N. S.; Cheng, C.-W.; Raijman, L. Channeling of extramitochondrial ornithine to matrix ornithine transcarbamylase. J. Biol. Chem. 1987, 262, 203-208.
15. Zollner, H. Ornithiner uptake by isolated hepatocytes and distribution within the cell. Int. J. Biochem. 1984, 16, 681-685.
16. Archibald, R. M. Colorimetric determination of urea. J. Biol. Chem. 1945, 157, 507-518.
17. McGivan, J. D.; Bradford, N. M.; Mendes-Mourao, J. The regulation of carbamoyl phosphate synthetase activity in rat liver mitochondria. Biochem. J. 1976, 154, 415-421.
18. Hayase, K.; Yonekawa, G.; Yoshida, A. Changes in liver concentration of N-acetylglutamate and ornithine are involved in regulating urea synthesis in rats treated with thyroid hormone. J. Nutr. 1992, 122, 1143-1148.
19. Millward, D. J.; Nnanyelugo, D. O.; James, W. P. T.; Garlick, P. J. Protein metabolism in skeletal muscle: The effect of feeding and fasting on muscle RNA, free amino acids and plasma insulin concentrations. Br. J. Nutr. 1974, 32, 127-142.
20. Shigesada, K.; Aoyagi, K.; Tatibana, M. Role of acetylglutamate in ureoterism. Variation in acetylglutamate level and its possible significance in control of urea synthesis in mammalian liver. Eur. J. Biochem. 1978, 85, 385-391.
21. Morita, T.; Mori, M.; Tatibana, M. Regulation of N-acetylglutamate degradation in mammalian liver. J. Biochem. 1982, 91, 563-569.
22. McGivan, J. D.; Bradford, N. M.; Beavis, A. D. Factors influencing the activity of ornithine transaminase in isolated liver mitochondria. Biochem. J. 1977, 162, 147-156.
23. Novicoff, A. B.; Hews, M. A microsomal nucleoside diphosphatase. J. Biol. Chem. 1963, 238, 710-716.
24. Duncan, D. B. Multiple range and multiple F tests. Biometrics 1955, 11, 1-42.
25. Snedecor, G. W.; Cochlan, W. G. Statistical Methods, 6th Ed.; Iowa State University Press: Ames, IA, 1967; pp 135-171.
26. Stewart, P. M.; Walser, M. Short term regulation of ureagenesis. J. Biol. Chem. 1980, 255, 5270-5280.
27. Hayase, K.; Yonekawa, G.; Yoshida, A. Arginine affects urea synthesis in rats treated with thiroid hormone. J. Nutr. 1993, 123, 253-258.
28. Hayase, K.; Naganuma, Y.; Koie, M.; Yoshida, A. Role of N-acetylglutamate turnover in urea synthesis by rats treated with the thyroid hormone. Biosci., Biotechnol., Biochem. 1998, 62, 535-539.
29. Hensgens, H. E. S. J.; Vorhoeven, A. J.; Meijer, A. J. The relationship between intramitochondrial N-acetylglutamate and activity of carbamoyl-phosphate synthetase (ammonia). Eur. J. Biochem. 1980, 107, 197-205.
30. Kamemoto, E. S.; Atkinson, D. E. Modulation of the activity of rat liver acetylglutamate synthetase by pH and arginine concentration. Arch. Biochem. Biophys. 1985, 243, 100-107.
31. Katunuma, N.; Okada, M.; Nishii, Y. Regulation of the urea cycle and TCA cycle by ammonia. In Advances in Enzyme Regulation; Weber, G., Ed.; Pergamon Press: New York, 1966; Vol 4, pp 317-335.
32. Raijman, L. Citrulline synthesis in the rat. Biochem. J. 1974, 138, 225-232.
33. Naganuma, Y.; Hayase, K.; Yoshida, A. Role of ornithine transport into mitochondria in urea synthesis of rats treated with thyroid hormone. J. Nutr. Sci. Vitaminol. 1997, 43, 387-396.
34. American Institute of Nutrition. AIN purified diets for laboratory rodents: Final report of the American Institute of Nutrition Ad Hoc Writing Committee on the reformulation of the AIN-76A rodent diet. J. Nutr. 1993, 123, 1939-1951.