Novel Lopinavir analogues incorporating non-Aromatic P-1 side chains - Synthesis and structure-activity relationships

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 21, 2002, Pages 3101-3103

  Sham, Hing L ^a   Zhao, Chen ^a   Li, Leping ^a   Betebenner, David A ^a   Saldivar, Ayda ^a   Vasavanonda, Sudthida ^a   Kempf, Dale J ^a   Plattner, Jacob J ^a   Norbeck, Daniel W ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,6 DIMETHYLPHENOXYACETIC ACID; ACETIC ACID DERIVATIVE; DRUG DERIVATIVE; LOPINAVIR; LOPINAVIR PLUS RITONAVIR; PROTEINASE; RITONAVIR; UNCLASSIFIED DRUG;

ARTICLE; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; STRUCTURE ACTIVITY RELATION;

CELL LINE; HIV PROTEASE INHIBITORS; HIV-1; HUMANS; MICROBIAL SENSITIVITY TESTS; PYRIMIDINONES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037020714     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00643-1     Document Type: Article

References (9)

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9. All compounds reported have mass, NMR, and analytical data consistent with the structures assigned.