메뉴 건너뛰기




Volumn 94, Issue 17, 2002, Pages 1275-1281

Herbal composition PC-SPES for management prostate cancer: Identification of active principles

Author keywords

[No Author keywords available]

Indexed keywords

BAICALIN; D 4628; DIETHYLSTILBESTROL; I 7378; INDOMETACIN; LICOCHALCONE A; NATURAL PRODUCT; PC SPES; PHYTOSTEROL; S 2424; S 9889; WARFARIN;

EID: 0037019735     PISSN: 00278874     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (97)

References (31)
  • 1
    • 0034330147 scopus 로고    scopus 로고
    • Prospective trial of the herbal supplement PC-SPES in patients with progressive prostate cancer
    • Small EJ, Frohlich MW, Bok R, Shinohara K, Grossfeld G, Rozenblat Z, et al. Prospective trial of the herbal supplement PC-SPES in patients with progressive prostate cancer. J Clin Oncol 2000;18:3595-603.
    • (2000) J. Clin. Oncol , vol.18 , pp. 3595-3603
    • Small, E.J.1    Frohlich, M.W.2    Bok, R.3    Shinohara, K.4    Grossfeld, G.5    Rozenblat, Z.6
  • 2
    • 0033822317 scopus 로고    scopus 로고
    • Herbal therapy PC-SPES: In vitro effects and evaluation of its efficacy in 69 patients with prostate cancer
    • de la Taille A, Buttyan R, Hayek O, Bagiella E, Shabsigh A, Burchardt M, et al. Herbal therapy PC-SPES: in vitro effects and evaluation of its efficacy in 69 patients with prostate cancer. J Urol 2000;164:1229-34.
    • (2000) J. Urol , vol.164 , pp. 1229-1234
    • de la Taille, A.1    Buttyan, R.2    Hayek, O.3    Bagiella, E.4    Shabsigh, A.5    Burchardt, M.6
  • 3
    • 0032541587 scopus 로고    scopus 로고
    • Clinical and biologic activity of an estrogenic herbal combination (PC-SPES) in prostate cancer
    • DiPaola RS, Zhang H, Lambert GH, Meeker R, Licitra E, Rafi MM, et al. Clinical and biologic activity of an estrogenic herbal combination (PC-SPES) in prostate cancer. N Engl J Med 1998;339:785-91.
    • (1998) N. Engl. J. Med , vol.339 , pp. 785-791
    • DiPaola, R.S.1    Zhang, H.2    Lambert, G.H.3    Meeker, R.4    Licitra, E.5    Rafi, M.M.6
  • 5
    • 0034295280 scopus 로고    scopus 로고
    • Chinese herbal mixture PC SPES in treatment of prostate cancer
    • Darzynkiewicz Z, Traganos F, Wu JM, Chen S. Chinese herbal mixture PC SPES in treatment of prostate cancer. Int J Oncol 2000;17:729-36.
    • (2000) Int. J. Oncol , vol.17 , pp. 729-736
    • Darzynkiewicz, Z.1    Traganos, F.2    Wu, J.M.3    Chen, S.4
  • 7
    • 0035212167 scopus 로고    scopus 로고
    • Baicalin is a major component of PC-SPES which inhibits the proliferation of human cancer cells via apoptosis and cell cycle arrest
    • Ikezoe T, Chen SS, Heber D, Taguchi H, Koeffler HP. Baicalin is a major component of PC-SPES which inhibits the proliferation of human cancer cells via apoptosis and cell cycle arrest. Prostate 2001;49:285-92.
    • (2001) Prostate , vol.49 , pp. 285-292
    • Ikezoe, T.1    Chen, S.S.2    Heber, D.3    Taguchi, H.4    Koeffler, H.P.5
  • 8
    • 0033861361 scopus 로고    scopus 로고
    • Modulation of bcl-2 and cytotoxicity by licochalcone-A, a novel estrogenic flavonoid
    • Rafi MM, Rosen RT, Vassil A, Ho CT, Zhang H, Ghai G, et al. Modulation of bcl-2 and cytotoxicity by licochalcone-A, a novel estrogenic flavonoid. Anticancer Res 2000;20:2653-8.
    • (2000) Anticancer Res , vol.20 , pp. 2653-2658
    • Rafi, M.M.1    Rosen, R.T.2    Vassil, A.3    Ho, C.T.4    Zhang, H.5    Ghai, G.6
  • 9
    • 84889167987 scopus 로고    scopus 로고
    • Agricultural Research Service (ARS). Dr. Duke's Phytochemical and Ethnobotanical Databases. U.S. Department of Agriculture-ARS-National Germplasm Resources Laboratory (NGRL), Beltsville, Maryland. [Last accessed: 7/19/02]. Available at
    • Agricultural Research Service (ARS). Dr. Duke's Phytochemical and Ethnobotanical Databases. U.S. Department of Agriculture-ARS-National Germplasm Resources Laboratory (NGRL), Beltsville, Maryland. [Last accessed: 7/19/02]. Available at: http://www.ars-grin.gov/cgi-bin/duke/farmacy2.pl?507.
  • 10
    • 0035909662 scopus 로고    scopus 로고
    • Acquired bleeding diathesis in a patient taking PC-SPES
    • Weinrobe MC, Montgomery B. Acquired bleeding diathesis in a patient taking PC-SPES. N Engl J Med 2001;345:1213-4.
    • (2001) N. Engl. J. Med , vol.345 , pp. 1213-1214
    • Weinrobe, M.C.1    Montgomery, B.2
  • 11
    • 0001180011 scopus 로고
    • Synthesis of licochalcone A
    • Islam A, Hossain MA. Synthesis of licochalcone A. Indian J Chem 1993;32B:713-5.
    • (1993) Indian J. Chem , vol.32 B , pp. 713-715
    • Islam, A.1    Hossain, M.A.2
  • 13
    • 84889131384 scopus 로고
    • International Union of Pure and Applied Chemistry, Applied Chemistry Division, Commission on Oils, Fat and Derivatives. Standard Methods for The Analysis of Oils, Fats, and Derivatives. 7th revised and enlarged edition. Determination of the total sterols content. Prepared for publication by Paquot C, Hautfenne A. Oxford (UK): Blackwell Scientific Publications
    • International Union of Pure and Applied Chemistry, Applied Chemistry Division, Commission on Oils, Fat and Derivatives. Standard methods for the analysis of oils, fats, and derivatives. 7th revised and enlarged edition. Determination of the total sterols content. Prepared for publication by Paquot C, Hautfenne A. Oxford (UK): Blackwell Scientific Publications; 1987. p. 170-3.
    • (1987) , pp. 170-173
  • 14
    • 0033399008 scopus 로고    scopus 로고
    • Comparison of colorimetric MTT and clonogenic assays for irradiation and cisplatin treatment on murine fibrosarcoma SA-1 cells
    • Cemazar M, Marolt D, Lavric M, et al. Comparison of colorimetric MTT and clonogenic assays for irradiation and cisplatin treatment on murine fibrosarcoma SA-1 cells. Radiol Oncol 1999;33:303-8.
    • (1999) Radiol. Oncol , vol.33 , pp. 303-308
    • Cemazar, M.1    Marolt, D.2    Lavric, M.3
  • 15
    • 0027365574 scopus 로고
    • MVLN cells: A bioluminescent MCF-7-derived cell line to study the modulation of estrogenic activity
    • Demirpence E, Duschesne MJ, Badia E, Gagne D, Pons M. MVLN cells: a bioluminescent MCF-7-derived cell line to study the modulation of estrogenic activity. J Steroid Biochem Mol Biol 1993;46:355-64.
    • (1993) J. Steroid. Biochem. Mol. Biol , vol.46 , pp. 355-364
    • Demirpence, E.1    Duschesne, M.J.2    Badia, E.3    Gagne, D.4    Pons, M.5
  • 16
    • 17944378660 scopus 로고    scopus 로고
    • Evaluation of estrogenic activity of plant extracts for the potential treatment of menopausal symptoms
    • Liu J, Burdette JE, Xu H, Gu C, van Breemen RB, Bhat KP, et al. Evaluation of estrogenic activity of plant extracts for the potential treatment of menopausal symptoms. J Agric Food Chem 2001;49:2472-9.
    • (2001) J. Agric. Food Chem , vol.49 , pp. 2472-2479
    • Liu, J.1    Burdette, J.E.2    Xu, H.3    Gu, C.4    van Breemen, R.B.5    Bhat, K.P.6
  • 17
    • 0034898838 scopus 로고    scopus 로고
    • The effects of phytotherapeutic agents on prostate cancer: An overview of recent clinical trials of PC SPES
    • Pirani JF. The effects of phytotherapeutic agents on prostate cancer: an overview of recent clinical trials of PC SPES. Urology 2001;58:36-8.
    • (2001) Urology , vol.58 , pp. 36-38
    • Pirani, J.F.1
  • 18
    • 0032145396 scopus 로고    scopus 로고
    • A phase II trial of oral diethylstilbestrol as a second-line hormonal agent in advanced prostate cancer
    • Smith DC, Redman BG, Flaherty LE, Li L, Strawderman M, Pienta KJ. A phase II trial of oral diethylstilbestrol as a second-line hormonal agent in advanced prostate cancer. Urology 1998;52:257-60.
    • (1998) Urology , vol.52 , pp. 257-260
    • Smith, D.C.1    Redman, B.G.2    Flaherty, L.E.3    Li, L.4    Strawderman, M.5    Pienta, K.J.6
  • 19
    • 0000324031 scopus 로고    scopus 로고
    • Diethylstilbestrol is an active agent in prostatic cancer patients after failure to complete androgen blockade
    • (abstract 1372)
    • Rosenbaum E, Wygoda M, Gips M, et al. Diethylstilbestrol is an active agent in prostatic cancer patients after failure to complete androgen blockade (abstract 1372). Proc ASCO 2000:19.
    • (2000) Proc. ASCO , pp. 19
    • Rosenbaum, E.1    Wygoda, M.2    Gips, M.3
  • 20
    • 0028876979 scopus 로고
    • Estrogens in the treatment of prostate cancer
    • Cox RL, Crawford ED. Estrogens in the treatment of prostate cancer. J Urol 1995;154:1991-8.
    • (1995) J. Urol , vol.154 , pp. 1991-1998
    • Cox, R.L.1    Crawford, E.D.2
  • 21
    • 0034909874 scopus 로고    scopus 로고
    • The role of diethylstilbestrol in the treatment of prostate cancer
    • Malkowicz SB. The role of diethylstilbestrol in the treatment of prostate cancer. Urology 2001;58:108-13.
    • (2001) Urology , vol.58 , pp. 108-113
    • Malkowicz, S.B.1
  • 22
    • 0015749215 scopus 로고
    • Proceedings: The Veterans Administration Cooperative Urological Research Group's studies of cancer of the prostate
    • Byar DP. Proceedings: The Veterans Administration Cooperative Urological Research Group's studies of cancer of the prostate. Cancer 1973;32: 1126-30.
    • (1973) Cancer , vol.32 , pp. 1126-1130
    • Byar, D.P.1
  • 23
    • 0023726635 scopus 로고
    • Hormone therapy for prostate cancer: Results of the Veterans Administration Cooperative Urological Research Group studies
    • Byar DP, Corle DK. Hormone therapy for prostate cancer: results of the Veterans Administration Cooperative Urological Research Group studies. NCI Monogr 1988;(7):165-70.
    • (1988) NCI Monogr , vol.7 , pp. 165-170
    • Byar, D.P.1    Corle, D.K.2
  • 24
    • 0025975826 scopus 로고
    • Megestrol acetate plus low-dose estrogen in the management of advanced prostatic carcinoma
    • Geller J. Megestrol acetate plus low-dose estrogen in the management of advanced prostatic carcinoma. Urol Clin North Am 1991;18:83-91.
    • (1991) Urol. Clin. North Am , vol.18 , pp. 83-91
    • Geller, J.1
  • 25
    • 0000568623 scopus 로고    scopus 로고
    • A prospective multicenter randomized trial of the herbal supplement, PC-SPES vs. diethylstilbestrol (DES) in patients with advanced, androgen independent prostate cancer (AiPCa)
    • Small EJ, Kantoff PW, Weinberg VK, Nguyen S, Smith M, Bubley GJ, et al. A prospective multicenter randomized trial of the herbal supplement, PC-SPES vs. diethylstilbestrol (DES) in patients with advanced, androgen independent prostate cancer (AiPCa). Proc ASCO 2002; 21:178a.
    • (2002) Proc. ASCO , vol.21
    • Small, E.J.1    Kantoff, P.W.2    Weinberg, V.K.3    Nguyen, S.4    Smith, M.5    Bubley, G.J.6
  • 27
    • 0032710325 scopus 로고    scopus 로고
    • Effects of intravenous administration of high dose diethylstilbestrol diphosphate on serum hormonal levels in patients with hormone-refractory prostate cancer
    • Kitahara S, Umeda H, Yano H. Effects of intravenous administration of high dose diethylstilbestrol diphosphate on serum hormonal levels in patients with hormone-refractory prostate cancer. Endocr J 1999;46: 659-64.
    • (1999) Endocr. J , vol.46 , pp. 659-664
    • Kitahara, S.1    Umeda, H.2    Yano, H.3
  • 28
    • 0016631215 scopus 로고
    • Correlation of anti-inflammatory activity with inhibition of prostaglandin synthesis activity of nonsteroidal anti-estrogens and estrogens (38532)
    • Lerner EJ, Carminati P, Schiatti P. Correlation of anti-inflammatory activity with inhibition of prostaglandin synthesis activity of nonsteroidal anti-estrogens and estrogens (38532). Proc Soc Exp Biol Med 1975;148: 329-32.
    • (1975) Proc. Soc. Exp. Biol. Med , vol.148 , pp. 329-332
    • Lerner, E.J.1    Carminati, P.2    Schiatti, P.3
  • 29
    • 0031799475 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibitors suppress the growth of gastric cancer xenografts via induction of apoptosis in nude mice
    • Sawaoka H, Kawano S, Tsuji S, Tsujii M, Gunawan ES, Takei Y, et al. Cyclooxygenase-2 inhibitors suppress the growth of gastric cancer xenografts via induction of apoptosis in nude mice. Am J Physiol 1998;274: G1061-7.
    • (1998) Am. J. Physiol , vol.274
    • Sawaoka, H.1    Kawano, S.2    Tsuji, S.3    Tsujii, M.4    Gunawan, E.S.5    Takei, Y.6
  • 30
    • 0018671719 scopus 로고
    • Timing of indomethacin in the control of prostaglandins, osteoclasts and bone destruction produced by VX2 carcinoma in rabbits
    • Galasko CS, Rawlins R, Bennett A. Timing of indomethacin in the control of prostaglandins, osteoclasts and bone destruction produced by VX2 carcinoma in rabbits. Br J Cancer 1979;40:360-4.
    • (1979) Br. J. Cancer , vol.40 , pp. 360-364
    • Galasko, C.S.1    Rawlins, R.2    Bennett, A.3
  • 31
    • 0032127153 scopus 로고    scopus 로고
    • Enhancement of chemotherapeutic drug toxicity to human tumour cells in vitro by a subset of non-steroidal anti-inflammatory drugs (NSAIDs)
    • Duffy CP, Elliott CJ, O'Connor RA, Heenan MM, Coyle S, Cleary IM, et al. Enhancement of chemotherapeutic drug toxicity to human tumour cells in vitro by a subset of non-steroidal anti-inflammatory drugs (NSAIDs). Eur J Cancer 1998;34:1250-9.
    • (1998) Eur. J. Cancer , vol.34 , pp. 1250-1259
    • Duffy, C.P.1    Elliott, C.J.2    O'Connor, R.A.3    Heenan, M.M.4    Coyle, S.5    Cleary, I.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.