SCOPUS 정보 검색 플랫폼

Volumn 239, Issue 1-2, 2002, Pages 207-211

Preformulation studies of a novel camptothecin anticancer agent, CKD-602: Physicochemical characterization and hydrolytic equilibrium kinetics

(5) Kim, Jae Hyun a Lee, Seok Kyu a Lim, Jong Lae a Shin, Hee Jong a Hong, Chung Il a

a Chong Kun Dang Research Institute (South Korea)

Author keywords

(20S) 7 (2 isopropylamino)ethylcamptothecin HCl; Anti cancer agent; pH dependent partition coefficient; Preformulation; Reversible hydrolysis

Indexed keywords

ANTINEOPLASTIC AGENT; BELOTECAN; BUFFER; CAMPTOTHECIN; CARBOXYLIC ACID; LACTONE; OCTANOL; WATER;

AQUEOUS SOLUTION; ARTICLE; DRUG DECOMPOSITION; DRUG HYDROLYSIS; DRUG SOLUBILITY; DRUG STABILITY; EQUILIBRIUM CONSTANT; HUMIDITY; HYDROLYSIS KINETICS; IONIZATION; MELTING POINT; PARTITION COEFFICIENT; PH; PHOTODEGRADATION; PHYSICAL CHEMISTRY; PREFORMULATION; PRIORITY JOURNAL; REACTION TIME; SOLID; THERMOGRAPHY; THERMOSTABILITY; WETTABILITY;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CALORIMETRY, DIFFERENTIAL SCANNING; CAMPTOTHECIN; CHEMISTRY, PHYSICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; HUMIDITY; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; SOLUBILITY; SOLVENTS; TEMPERATURE;

EID: 0037018966 PISSN: 03785173 EISSN: None Source Type: Journal
DOI: 10.1016/S0378-5173(02)00099-6 Document Type: Article

Times cited : (10)

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