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Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 11, 2002, Pages 1537-1541

CoMFA and HQSAR of acylhydrazide cruzain inhibitors

(5) Rodrigues, Carlos R a,b Flaherty, Terrence M b Springer, Clayton b McKerrow, James H b Cohen, Fred E b

a FEDERAL UNIVERSITY OF RIO DE JANEIRO (Brazil)

b UNIVERSITY OF CALIFORNIA (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRUZIPAIN; HYDRAZIDE DERIVATIVE; CRUZAIN, TRYPANOSOMA CRUZI; CYSTEINE PROTEINASE; CYSTEINE PROTEINASE INHIBITOR; HYDRAZINE DERIVATIVE; LIGAND; PROTOZOAL PROTEIN;

ANALYTIC METHOD; ARTICLE; HOLOGRAPHY; MOLECULAR MODEL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; VALIDATION PROCESS; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; CONFORMATION; DRUG ANTAGONISM; DRUG DESIGN; ENZYMOLOGY; IC 50; INSTRUMENTATION; METABOLISM; METHODOLOGY; THREE DIMENSIONAL IMAGING; TRYPANOSOMA CRUZI;

ANIMALS; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; DRUG DESIGN; HYDRAZINES; IMAGING, THREE-DIMENSIONAL; INHIBITORY CONCENTRATION 50; LIGANDS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PROTOZOAN PROTEINS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOSOMA CRUZI;

EID: 0037013438 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/S0960-894X(02)00189-0 Document Type: Article

Times cited : (45)

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