The heat capacity paradox of ligand binding proteins: Reconciling the microscopic and macroscopic world

Biophysical Chemistry

Volumn 96, Issue 2-3, 2002, Pages 109-116

  Rösgen, Jörg ^a   Hinz, Hans Jürgen ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Calorimetry; Grand canonic; Ligand binding; Partition function; Statistical thermodynamics

Indexed keywords

LIGAND; M PROTEIN; PROTEIN;

ARTICLE; BINDING AFFINITY; CALCULATION; DATA ANALYSIS; DIFFERENTIAL SCANNING CALORIMETRY; ENERGY TRANSFER; HEAT; LIGAND BINDING; MICROSCOPY; MODEL; PARTITION COEFFICIENT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FOLDING; SIGNAL TRANSDUCTION; THERMODYNAMICS; CHEMICAL MODEL; CHEMISTRY; METABOLISM; PROTEIN BINDING;

CALORIMETRY, DIFFERENTIAL SCANNING; LIGANDS; MODELS, CHEMICAL; PROTEIN BINDING; PROTEINS; THERMODYNAMICS;

EID: 0037007463     PISSN: 03014622     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-4622(02)00016-9     Document Type: Article

References (17)

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6. Allosteric formulation of thermal transitions in macromolecules, including effects of ligand binding and oligomerization
7. Study of strong to ultratight protein interactions using differential scanning calorimetry
8. Two-dimensional differential scanning calorimetry: Simultaneous resolution of intrinsic protein structural energetics and ligand binding interactions by global linkage analysis
9. Scanning microcalorimetry in studying temperature-induced changes in proteins
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12. The 'Janus' nature of proteins
13. Statistical thermodynamic treatment of conformational transitions of monomeric and oligomeric proteins
14. Folding energetics of ligand binding proteins I: Theoretical model
15. Ligand-induced biphasic protein denaturation
16. Origins and consequences of ligand-induced multiphasic thermal protein denaturation
17. 2+ to annexin I