HEPC-based liposomes trigger cytokine release from peripheral blood cells: Effects of liposomal size, dose and lipid composition

International Journal of Pharmaceutics

Volumn 236, Issue 1-2, 2002, Pages 125-133

  Yamamoto, Sayaka ^a   Ishida, Tatsuhiro ^a   Inoue, Akiko ^a   Mikami, Junko ^a   Muraguchi, Masahiro ^a,b   Ohmoto, Yasukazu ^b   Kiwada, Hiroshi ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b OTSUKA PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Cytokine; Human peripheral blood cell; Immune system; Liposome; Whole blood induction

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; BREFELDIN A; CYTOCHALASIN B; GAMMA INTERFERON; HERBIMYCIN A; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOSOME; PHOSPHATIDYLCHOLINE; PLASMA PROTEIN; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BLOOD CELL; CELL STIMULATION; CELLULAR IMMUNITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG DELIVERY SYSTEM; DRUG EFFECT; DRUG MECHANISM; EGG; ENDOCYTOSIS; HUMAN; HUMAN CELL; HYDROGENATION; LIPID COMPOSITION; MONONUCLEAR CELL; NORMAL HUMAN; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN INDUCTION; SIGNAL TRANSDUCTION;

CYTOKINES; DOSAGE FORMS; EGGS; HUMANS; HYDROGENATION; LEUKOCYTES, MONONUCLEAR; LIPOSOMES; PARTICLE SIZE; PHOSPHATIDYLCHOLINES;

EID: 0037006921     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(02)00026-1     Document Type: Article

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