Inhibition of cytochrome c oxidase activity in rat cerebral cortex and human skeletal muscle by D-2-hydroxyglutaric acid in vitro

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1586, Issue 1, 2002, Pages 81-91

  Da Silva, Cleide G ^a   Ribeiro, César A J ^a   Leipnitz, Guilhian ^a   Dutra Filho, Carlos S ^a   Wyse, Ângela T S ^a   Wannmacher, Clóvis M D ^a   Sarkis, João J F ^a   Jakobs, Cornelis ^b   Wajner, Moacir ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Brain metabolism; Cytochrome c oxidase; D 2 Hydroxyglutaric acid; L 2 Hydroxyglutaric acid

Indexed keywords

CARBON DIOXIDE; CYTOCHROME C OXIDASE; DEXTRO 2 HYDROXYGLUTARIC ACID; GLUTARIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ACIDURIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN HOMOGENATE; BRAIN METABOLISM; BRAIN SLICE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENERGY METABOLISM; ENZYME ACTIVITY; EVALUATION; GLUCOSE TRANSPORT; GLUCOSE UTILIZATION; HUMAN; IN VITRO STUDY; MEASUREMENT; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; RAT; RESPIRATORY CHAIN; SKELETAL MUSCLE;

ANIMALS; CARBON DIOXIDE; CEREBRAL CORTEX; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRON TRANSPORT COMPLEX III; ELECTRON TRANSPORT COMPLEX IV; ENERGY METABOLISM; GLUCOSE; GLUTARATES; HUMANS; KINETICS; MUSCLE, SKELETAL; RATS; STEREOISOMERISM;

RATTUS NORVEGICUS;

EID: 0037005823     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4439(01)00088-6     Document Type: Article

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