Lipophilicity and other parameters affecting brain penetration

Current Medicinal Chemistry - Central Nervous System Agents

Volumn 2, Issue 3, 2002, Pages 229-240

  Atkinson, F ^a   Cole, S ^a   Green, C ^a   Van de Waterbeemd, H ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; GLYCOPROTEIN P; SOLVENT; SUGAR;

ACTIVE TRANSPORT; AQUEOUS SOLUTION; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CELL; CELL MEMBRANE PERMEABILITY; CELL TRANSPORT; CEREBROSPINAL FLUID; CONCENTRATION RESPONSE; DIFFUSION; DRUG PENETRATION; DRUG TARGETING; DRUG TRANSPORT; ENERGY; EXTRACELLULAR FLUID; HYDROGEN BOND; LIPOPHILICITY; MEASUREMENT; MOLECULAR SIZE; PASSIVE TRANSPORT; POLARIZATION; TIGHT JUNCTION;

EID: 0037004945     PISSN: 15680150     EISSN: None     Source Type: Journal    
DOI: 10.2174/1568015023358058     Document Type: Article

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