Cerebellar volumes in newly diagnosed and chronic epilepsy

Journal of Neurology

Volumn 249, Issue 12, 2002, Pages 1651-1658

  Hagemann, G ^a,b   Lemieux, L ^c,d   Free, S L ^c,d   Krakow, K ^c,d   Everitt, A D ^c,d   Kendall, B E ^c,d,e   Stevens, J M ^c,d,e   Shorvon, S D ^c,d  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^b HEINRICH HEINE UNIVERSITY   (Germany)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d EPILEPSY SOCIETY   (United Kingdom)

^e NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

Author keywords

Atrophy; Cerebellum; Epilepsy; MRI volumetry

Indexed keywords

ANTICONVULSIVE AGENT;

ADULT; ANALYTIC METHOD; ARTICLE; BRAIN REGION; BRAIN SIZE; CEREBELLUM ATROPHY; CLINICAL TRIAL; COHORT ANALYSIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE SEVERITY; EPILEPSY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PREVALENCE; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUANTITATIVE ANALYSIS; RELIABILITY; TONIC CLONIC SEIZURE; VOLUMETRY;

ADOLESCENT; ADULT; ANALYSIS OF VARIANCE; CEREBELLUM; CHRONIC DISEASE; CONFIDENCE INTERVALS; EPILEPSY; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RETROSPECTIVE STUDIES; STATISTICS, NONPARAMETRIC;

EID: 0037004883     PISSN: 03405354     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00415-002-0843-9     Document Type: Article

References (39)

1. Specht U, May T, Schulz R, et al. (1997) Cerebellar atrophy and prognosis after temporal lobe resection. J Neurol Neurosurg Psychiatry 62:501-506
2. Kuruvilla T, Bharucha NE (1997) Cerebellar atrophy after acute phenytoin intoxication, Epilepsia 38:500-502
3. Specht U, May TW, Rohde M, et al. (1997) Cerebellar atrophy decreases the threshold of carbamazepine toxicity in patients with chronic focal epilepsy. Arch Neurol 54:427-431
4. Luef G, Chemelli A, Birbamer G, et al. (1994) Phenytoin overdosage and cerebellar atrophy in epileptic patients: clinical and MRI findings. Eur Neurol 34(Suppl 1):79-81
5. McLain LW, Jr, Martin JT, Allen JH (1980) Cerebellar degeneration due to chronic phenytoin therapy. Ann Neurol 7:18-23
6. Ney GC, Lantos G, Barr WB, et al. (1994) Cerebellar atrophy in patients with long-term phenytoin exposure and epilepsy. Arch Neurol 51:767-771
7. Ghatak NR, Santoso RA, McKinney WM (1976) Cerebellar degeneration following long-term phenytoin therapy. Neurology 26:818-820
8. Rapport RL, Shaw CM (1977) Phenytoin-related cerebellar degeneration without seizures. Ann Neurol 2:437-439
9. Sandok EK, O'Brien TJ, Jack CR, et al. (2000) Significance of cerebellar atrophy in intractable temporal lobe epilepsy: a quantitative MRI study (In Process Citation). Epilepsia 41:1315-1320
10. Berquin PC, Giedd JN, Jacobsen LK, et al. (1998) Cerebellum in attention-deficit hyperactivity disorder: a morphometric MRI study. Neurology 50:1087-1093
11. Cooper IS, Upton AR (1978) Use of chronic cerebellar stimulation for disorders of disinhibition. Lancet 1:595-600
12. Davis R, Emmonds SE (1992) Cerebellar stimulation for seizure control: 17-year study. Stereotact Funct Neurosurg 58:200-208
13. Lawson JA, Vogrin S, Bleasel AF, et al. (2000) Cerebral and cerebellar volume reduction in children with intractable epilepsy. Epilepsia 41:1456-1462
14. Price RH, Albin RL, Sakurai SY, et al. (1993) Cerebellar excitatory and inhibitory amino acid receptors in multiple system atrophy. Neurology 43:1323-1328
15. Masur H, Fahrendorf G, Oberwittler C, et al. (1990) Cerebellar atrophy following acute intoxication with phenytoin. Neurology 40:1800-1801
16. Bohnen NI, O'Brien TJ, Mullan BP, et al. (1998) Cerebellar changes in partial seizures: clinical correlations of quantitative SPECT and MRI analysis. Epilepsia 39:640-650
17. Young GB, Oppenheimer SR, Gordon BA, et al. (1994) Ataxia in institutionalized patients with epilepsy. Can J Neurol Sci 21:252-258
18. Luef G, Burtscher J, Kremser C, et al. (1996) Magnetic resonance volumetry of the cerebellum in epileptic patients after phenytoin overdosages. Eur Neurol 36:273-277
19. Masur H, Elger CE, Ludolph AC, et al. (1989) Cerebellar atrophy following acute intoxication with phenytoin. Neurology 39:432-433
20. Strassburger TL, Lee HC, Daly EM, et al. (1997) Interactive effects of age and hypertension on volumes of brain structures. Stroke 28:1410-1417
21. Pfefferbaum A, Mathalon DH, Sullivan EV, et al. (1994) A quantitative magnetic resonance imaging study of changes in brain morphology from infancy to late adulthood. Arch Neurol 51:874-887
22. Fox NC, Freeborough PA (1997) Brain atrophy progression measured from registered serial MRI: validation and application to Alzheimer's disease. J Magn Reson Imaging 7:1069-1075
23. Luft AR, Skalej M, Welte D, et al. (1998) A new semiautomated, three-dimensional technique allowing precise quantification of total and regional cerebellar volume using MRI. Magn Reson Med 40:143-151
24. Specht U, Rohde M, May T, et al. (1994) Cerebellar atrophy does not increase susceptibility to carbamazepine toxicity. Acta Neurol Scand 89:1-4
25. Moran NF, Lemieux L, Maudgil DD, et al. (1999) Analysis of Temporal Lobe Resections in MR Images. Epilepsia 40:1077-1084
26. Everitt A, Birnie K, Bell G, et al. (1999) Hippocampal sclerosis in newly diagnosed and chronic active epilepsy: a prospective population-based MRI study of its frequency and severity. Epilepsia 40(Suppl.2):41
27. Wieshmann UC, Free SL, Everitt AD, et al. (1996) Magnetic resonance imaging in epilepsy with a fast FLAIR sequence. J Neurol Neurosurg Psychiatry 61:357-361
28. Lemieux L, Wieshmann UC, Moran NF, et al. (1998) The detection and significance of subtle changes in mixed-signal brain lesions by serial MRI scan matching and spatial normalization. Med Image Anal 2:227-242
29. Sled JG, Zijdenbos AP, Evans AC (1998) A nonparametric method for automatic correction of intensity nonuniformity in MRI data. IEEE Trans Med Imaging 17:87-97
30. Mayhew TM, Olsen DR (1991) Magnetic resonance imaging (MRI) and model-free estimates of brain volume determined using the Cavalieri principle. J Anat 178:133-144
31. Raz N, Dupuis JH, Briggs SD, et al. (1998) Differential effects of age and sex on the cerebellar hemispheres and the vermis: a prospective MR study. Am J Neuroradiol 19:65-71
32. Blatter DD, Bigler ED, Gale SD, et al. (1995) Quantitative volumetric analysis of brain MR: normative database spanning 5 decades of life. Am J Neuroradiol 16:241-251
33. Fox NC, Freeborough PA, Rossor MN (1996) Visualisation and quantification of rates of atrophy in Alzheimer's disease. Lancet 348:94-97
34. Raz N, Gunning-Dixon F, Head D, et al. (2001) Age and sex differences in the cerebellum and the ventral pons: a prospective MR study of healthy adults. AJNR Am J Neuroradiol 22:1161-1167
35. Luft AR, Skalej M, Schulz JB, et al. (1999) Patterns of age-related shrinkage in cerebellum and brainstem observed in vivo using three-dimensional MRI volumetry. Cereb Cortex 9:712-721
36. Baron JC (1993) Crossed cerebellar diaschisis and atrophy: the role of intractable seizures. Am J Roentgenol 160:1152-1152
37. Tien RD, Ashdown BC (1992) Crossed cerebellar diaschisis and crossed cerebellar atrophy: correlation of MR findings, clinical symptoms, and supratentorial diseases in 26 patients. Am J Roentgenol 158:1155-1159
38. Yamauchi H, Fukuyama H, Nagahama Y, et al. (1999) A decrease in regional cerebral blood volume and hematocrit in crossed cerebellar diaschisis. Stroke 30:1429-1431
39. Chung HD (1985) Retrograde crossed cerebellar atrophy. Brain 108(Pt 4):881-895