Oral antidiabetic activities of different extracts of Caesalpinia bonducella seed kernels

Pharmaceutical Biology

Volumn 40, Issue 8, 2002, Pages 590-595

  Parameshwar, Sudeep ^a   Srinivasan, K K ^b   Rao, C Mallikarjuna ^a  

^a KASTURBA MEDICAL COLLEGE   (India)

^b MANIPAL COLLEGE OF PHARMACEUTICAL SCIENCES   (India)

Author keywords

Alloxan induced diabetes; Antidiabetic; Antioxidants; Caesalpinia bonducella F.; Hypoglycaemic effect; Seed kernels

Indexed keywords

ACETIC ACID ETHYL ESTER; ALCOHOL; CAESALPINIA BONDUCELLA EXTRACT; ETHER; GLIBENCLAMIDE; GLYCOSIDE; ORAL ANTIDIABETIC AGENT; PETROLEUM ETHER; PLANT EXTRACT; SCAVENGER; TRITERPENOID; UNCLASSIFIED DRUG;

ALLOXAN DIABETES MELLITUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; AQUEOUS SOLUTION; ARTICLE; CAESALPINIA BONDUCELLA; CARIBBEAN ISLANDS; CONTROLLED STUDY; DIABETES MELLITUS; DRUG ISOLATION; GLUCOSE BLOOD LEVEL; GLYCOGEN LIVER LEVEL; INDIA; LIPID BLOOD LEVEL; MALE; MEDICINAL PLANT; NONHUMAN; OXIDATIVE STRESS; POWDER; RAT; SEED KERNEL; TRADITIONAL MEDICINE;

ANIMALIA; CAESALPINIA; CAESALPINIA BONDUCELLA; FABACEAE;

EID: 0037003285     PISSN: 13880209     EISSN: None     Source Type: Journal    
DOI: 10.1076/phbi.40.8.590.14656     Document Type: Article

References (18)

1. Baynes JW (1991): Role of oxidative stress in development of complications in diabetes. Diabetes 40: 405-412.
2. Biswas TK, Bandyopadhyay S, Biswapati M, Bhaswar M, Sengupta BR (1997): Oral hypoglycaemic effect of Caesalpinia bonducella. Int J Pharmacog 35: 261-264.
3. Chattopadhyay S, Ramanathan M, Das J, Bhattacharya SK (1997): Animal models in experimental diabetes mellitus. Ind J Exptl Biol 35: 1141-1145.
4. Dhar ML, Dhar MM, Dhawan BN, Mehrotra BN, Roy C (1968): Screening of Indian plants for biological activity. Ind J Exptl Biol 6: 232-247.
5. Ghosh MN (1984): Toxicity studies. In: Ghosh MN, ed., Fundamentals of Experimental Pharmacology. Calcutta, Scientific Book Agenc, pp. 153-158.
6. Hideaki K, Kajimoto Y, Miyagawa J, Matsuoka T, Fujitani Y, Umayahara Y, Hanafusa T, Matsuzawa Y, Yamasaki Y (1999): Beneficial effects of antioxidants in diabetes. Diabetes 48: 2398-2401.
7. Ivorra MD, Paya M, Villar A (1989): A review of natural products and plants as potential antidiabetic drugs. J Ethnopharmacol 27: 243-275.
8. Iyengar MA, Pendse GS (1965): Anti-diarrhoeal activity of the nut of Caesalpinia bonducella. Flem. Ind J Pharm 27: 307-308.
9. Kato K, Terao S, Shimamoto N, Hirata M (1988): Studies on scavengers of active oxygen species, synthesis and biological activity of 2-O-alkyl ascorbic acid. J Med Chem 31: 793-798.
10. Larkins RG, Dunlop ME (1992): The link between hyperglycaemia and diabetic nephropathy. Diabetologia 35: 499-504.
11. Neogi NC, Nayak KP (1958): Biological investigation of Caesalpinia bonducella Flem. Ind J Pharm 20: 95-100.
12. Nicholas V (1956): The determination of glycogen in liver and muscle by use of anthrone reagent. Ind J Biol Chem 220: 583.
13. Paget GE, Burnes JM (1964): Toxicity tests. In: Lawrence DR, Bucharach AL, eds., Evaluation of Drug Activities. New York, Academic Press, 148 pp.
14. Peter S, Tinto WF, McLean S, Reynolds WF, Yu M (1998): Cassane diterpenes from Caesalpinia bonducella. Phytochemistry 47: 1153-1155.
15. Raghunathan K, Mitra R (1982): Caesalpinia bonducella. In: Raghunathan K, Mitra R, eds., Pharmacognosy of Indigenous Drugs. New Delhi, Central Council for Research in Ayurveda and Siddha, pp. 484-487.
16. Rao VV, Dwivedi SK, Swarup D (1994): Hypoglycaemic effect of Caesalpinia bonducella in rabbits. Fitoterapia 65: 245-247.
17. Sato Y, Hotta N, Sakamoto N, Matsuoka S (1979): Lipid peroxide level in plasma of diabetic patients. Biochem Med 21: 104-107.
18. Sharma SR, Dwivedi SK, Swarup D (1997): Hypoglycaemic, antihyperglycaemic and hypolipidemic activities of Caesalpinia bonducella seeds in rats. J Ethnopharmacol 58: 39-44.