Natural influenza a virus infection of mice elicits strong antibody response to HA2 glycopolypeptide

Acta Virologica

Volumn 46, Issue 4, 2002, Pages 229-236

  Kostolansky F ^a   Mucha, V ^a   Slovakova R ^a   Vareckova E ^a  

^a INSTITUTE OF VIROLOGY   (Slovakia)

Author keywords

Antibody response; HA2 glycopolypeptide; Influenza vaccine; Mouse adapted influenza virus; Natural influenza infection

Indexed keywords

HA2 GLYCOPOLYPEPTIDE; INFLUENZA VACCINE; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VIRUS ANTIGEN; VIRUS HEMAGGLUTININ;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; INFLUENZA VACCINATION; INFLUENZA VIRUS A; LD 50; MOUSE; NONHUMAN; VIRUS STRAIN;

ANIMALS; ANTIBODIES, VIRAL; ANTIBODY SPECIFICITY; DISEASE MODELS, ANIMAL; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; IMMUNIZATION; INFLUENZA A VIRUS; MICE; MICE, INBRED BALB C; ORTHOMYXOVIRIDAE; ORTHOMYXOVIRIDAE INFECTIONS; PEPTIDES;

ANIMALIA; INFLUENZA A VIRUS; INFLUENZA VIRUS; INFLUENZAVIRUS A;

EID: 0036998197     PISSN: 0001723X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Brand CM, Skehel JJ (1972): Crystalline antigen from the influenza virus envelope. Nature New Biol. 238, 145-147.
2. Becht H, Huang RTC, Fleischer B, Boshek CB, Rott R (1984): Immunogenic properties of the small chain HA2 of the hemagglutinin of influenza viruses. J. Gen. Virol. 65, 173-183.
3. Both GW, Sleigh MJ, Cox NJ, Kendal AP (1983): Antigenic drift in influenza virus H3 haemagglutinin from 1968 to 1980. Multiple evolutionary pathways and sequential amino acid changes at key antigenic sites. J. Virol. 48, 52-60.
4. Brown LE, Dopheide TAA, Ward CW, White DO, Jackson DC (1980): Antigenic determinants of influenza virus hemagglutinin. V. Antigenicity of the HA2 chain. J. Immunol. 125, 1583-1588.
5. 2) folds in Escherichia coli into the low-pH-induced conformation. Proc. Natl. Acad. Sci. USA 92, 12205-12209.
6. Daniels RS, Douglas AR, Skehel JJ, Wiley DC (1983): Analysis of the antigenicity of influenza haemagglutinin at the pH optimum for virus-mediated membrane fusion. J. Gen. Virol. 64, 1657-1662.
7. Eckert TA (1973): Properties of an antigenic glycoprotein isolated from influenza virus hemagglutinin. J. Virol. 11, 183-192.
8. Graves PN, Schulman JL, Young JF, Palese P (1983): Preparation of influenza virus subviral particles lacking the HA1 subunit of hemagglutinin: unmasking of cross-reactive HA2 determinants. Virology 126, 106-116.
9. Joassin L, Reginster, M, Vaira D (1983): Anti M-protein antibody response to type A or B natural influenza detected by solid phase enzyme linked immunosorbent assay and by complement fixation. Arch. Virol. 76, 15-23.
10. Johansson BE, Kilbourne ED (1996): Immunization with dissociated neuraminidase, matrix, and nucleoproteins from influenza A virus eliminates cognate help and antigenic competition. Virology 225, 1136-1144.
11. Khristova ML, Egorenkova EM, Busse TL, Leonov SV, Demidova SA, Kharintonenkov IG (1988): Simultaneous determination of the level of antibodies to influenza virus surface and internal proteins by enzyme-linked immunosorbent assay. Acta Virol. 32, 109-116.
12. Kostolanský F, Russ G, Mucha V, Styk B (1988): Changes in the influenza virus haemagglutinin at acid pH detected by monoclonal antibodies to glycopolypeptides HA1 and HA2. Arch. Virol. 101, 13-24.
13. Kostolanský F, Mucha V, Betáková T, Varečková E (1994): Antibody response to hidden epitope of influenza A haemagglutinin elicited by anti-idiotypic antibodies. Acta Virol. 38, 215-222.
14. Nobusawa E, Aoyama T, Kato H, Suzuki Y, Tateno Y, Nakajima K (1991): Comparison of complete amino acid sequences and receptor-binding properties among 13 serotypes of hemagglutinins of influenza A viruses. Virology 182, 475-485.
15. Ruigrok RWH, Martin SR, Wharton SA, Skehel JJ, Bayley PM, Wiley DC (1986): Conformational changes in hemagglutinin of influenza virus which accompany heat-induced fusion of virus with liposomes. Virology 155, 484-497.
16. Russ G, Varečková E, Styk B (1974): Steric effects in the reaction of influenza virus neuraminidases with antibodies. Acta Virol. 18, 299-306.
17. Russ G, Styk B, Poláková K (1978): Antigenic glycopolypeptides HA1 and HA2 of influenza virus haemagglutinin. II. Reactivity with rabit sera against intact virus and purified undissociated haemagglutinin. Acta Virol. 22, 371-382.
18. Russ G, Poláková K, Kostolanský F, Styk B, Vančiková M (1987): Monoclonal antibodies to glycopolypeptides HA1 and HA2 of influenza virus haemagglutinin. Acta Virol. 31, 374-386.
19. Sánchez-Fauqier A, Villaneuva N, Melero JA (1987): Isolation of cross-reactive, subtype-specific monoclonal antibodies against influenza virus HA1 and HA2 haemagglutinin subunits. Arch. Virol. 97, 251-265.
20. Scherle PA, Gerhard W (1988): Differential ability of B cells specific for external vs. internal influenza virus proteins to respond to help from influenza virus-specific T-cell clones in vivo. Proc. Natl. Acad. Sci. USA 85, 4446-4450.
21. Skehel JJ, Bailey PM, Brown EB, Martin SR, Waterfield MD, White J, Wilson IA, Wiley DC (1982): Changes in the conformation of influenza virus hemagglutinin at the pH optimum of virus-mediated membrane fusion. Proc. Natl. Acad. Sci. USA 79, 968-972.
22. Skehel JJ, Wiley DC (2000): Receptor binding and membrane fusion in virus entry: the influenza haemagglutinin. Ann. Rev. Biochem. 69, 531-569.
23. Styk B, Russ G, Poláková K (1979a): Antigenic glycopolypeptides HA1 and HA2 of influenza virus haemagglutinin. III. Reactivity with human convalescent sera. Acta Virol. 23, 1-8.
24. Styk B, Russ G, Poláková K (1979b): Antigenic glycopolypeptides HA1 and HA2 of influenza virus hemagglutinin. IV. Immunogenic properties of separated hemagglutinin glycopolypeptides. Acta Virol. 23, 9-20.
25. Sukeno N, Otsuki Y, Konno J, Yamane N, Odagiri T, Arikawa J, Ishida N (1979): Anti-nucleoprotein antibody response in influenza A infection. J. Exp. Med. 128, 241-249.
26. Varečková E, Mucha V, Čiampor F, Betáková T, Russ G (1993): Monoclonal antibodies demonstrate accessible HA2 epitopes in minor subpopulation of native influenza virus haemagglutinin molecules. Arch. Virol. 130, 45-56.
27. Varečková E, Cox N, Klimov A (2002): Evaluation of the subtype monoclonal antibodies raised against H1 and H3 subtypes of human influenza A virus hemagglutinins. J. Clin. Microbiol. 40, 2220-2223.
28. Varečková E, Mucha V, Wharton SA, Kostolanský F (2003): Inhibition of fusion activity of influenza A haemagglutinin mediated by HA2-specific monoclonal antibodies. Arch. Virol. (in press, DOI 10.1007/s00705-002-0932-1).
29. Webster RG, Brown LE, Jackson DC (1983): Changes in the antigenicity of the hemagglutinin molecule of H3 influenza virus at acidic pH. Virology 126, 587-599.
30. Wharton SA, Weis W, Skehel JJ, Wiley DC (1989): Structure, function and antigenicity of the haemagglutinin of influenza virus. In Krug RM (Eds): The Influenza Viruses. Plenum Press, New York-London, pp. 153-174.
31. Wiley DC, Skehel JJ (1987): The structure and function of the haemagglutinin membrane glycoprotein of influenza virus. Annu. Rev. Biochem. 56, 365-394.
32. Wiley DC, Wilson IA, Skehel JJ (1981): Structural identification of the antibody-binding sites of Hong Kong influenza haemagglutinin and their involvement in antigenic variation. Nature 289, 373-378.
33. Yewdell JW, Gerhard W, Bachi T (1983): Monoclonal anti-hemagglutinin antibodies detect irreversible antigenic alterations that coincide with the acid activation of influenza virus A/PR/8-mediated hemolysis. J. Virol. 48, 239-248.