Modulators of axonal growth and guidance at the brain midline with special reference to glial heparan sulfate proteoglycans

Anais da Academia Brasileira de Ciencias

Volumn 74, Issue 4, 2002, Pages 691-716

  Cavalcante, Leny A ^a   Garcia Abreu, José ^a   Neto, Vivaldo Moura ^a   Silva, Luiz Claudio ^a   Weissmüller, Gilberto ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Astrocytes; Axon growth; Extracellular matrix; Heparan sulfate; Midbrain; Midline

Indexed keywords

NERVE GROWTH FACTOR; PROTEOHEPARAN SULFATE;

ANIMAL; ASTROCYTE; CELL DIVISION; CYTOLOGY; GLIA; HUMAN; MESENCEPHALON; METABOLISM; NERVE FIBER; NEURITE; PHYSIOLOGY; REVIEW;

ANIMALS; ASTROCYTES; AXONS; CELL DIVISION; HEPARAN SULFATE PROTEOGLYCANS; HUMANS; MESENCEPHALON; NERVE GROWTH FACTORS; NEURITES; NEUROGLIA;

EID: 0036985638     PISSN: 00013765     EISSN: None     Source Type: Journal    
DOI: 10.1590/S0001-37652002000400010     Document Type: Article

References (170)

1. ANDERSON RB, WALZ HOLT CE AND KEY B. 1998. Chondroitin sulfates modulate axon guidance in embryonic Xenopus brain. Dev Biol 202: 235-243.
2. ANDERSON RB, COOPER HM, JACKSON SC, SEAMAN C AND KEY B. 2000. DCC plays a role in navigation of forebrain axons across the ventral midbrain commissure in embryonic Xenopus. Dev Biol 217: 244-253.
3. APKARIAN P, BOUR LJ, BARTH PG, WENNIGER-PRICK L AND VERBEETEN B JR. 1995. Non-decussating retinal-fugal fibre syndrome. An inborn achiasmatic malformation associated with visuotopic misrouting, visual evoked potential ipsilateral asymmetry and nystagmus. Brain 118: 1195-1216.
4. ASHER RA, MORGENSTERN DA, FIDLER PS, ADCOCK KH, OOHIRA A, BRAISTEAD JE, LEVINE JM, MARGOLIS RU, ROGERS JH AND FAWCETT JW. 2000. Neurocan is upregulated in injured brain and in cytokine-treated astrocytes. J Neurosci 20: 2427-2438.
5. BA-CHARVET KTN AND CHÉDOTAL A. 2002. Role of Slit proteins in the vertebrate brain. J Physiol (Paris) 96: 91-98.
6. BAGRI A, MARIN O, PLUMP AS, MAK J, PLEASURE SJ, RUBENSTEIN JLR AND TESSIER-LAVIGNE M. 2002. Slit proteins prevent midline crossing and determine the dorsoventral position of major axonal pathways in the mammalian forebrain. Neuron 33: 233-248.
7. BANDTLOW CE AND ZIMMERMANN DR. 2000. Proteoglycans in the developing brain: New conceptual insights for old proteins. Physiol Rev 80: 1267-1290.
8. BANSAL R, KUMAR M, MURRAY K AND PFEIFFER SE. 1996. Developmental and FGF-2-mediated regulation of syndecans (1-4) and glypican in oligodendrocytes. Mol Cell Neurosci 7: 276-288.
9. BARNEA G, GRUMET M, MILEV P, SILVENNOINEN O, LEVY JB, SAP J AND SCHLESSINGER J. 1994. Receptor tyrosine phosphatase beta is expressed in the form of proteoglycan and binds to the extracellular matrix protein tenascin. J Biol Chem 269: 14349-14352.
10. BARRADAS PC, CAVALCANTE LA, MENDEZ-OTERO R AND VIEIRA AM. 1989. Astroglial differentiation in the opossum superior colliculus. Glia 2: 103-111.
11. BENNETT KL, BRADSHAW J, YOUNGMAN T, RODGERS J, GREENHELD B, ARUFFO A AND LINSLEY PS. 1997. Deleted in colorectal carcinoma (DCC) binds heparin via its fifth fibronectin type III domain. J Biol Chem 272: 26940-26946.
12. BERNHARDT RR. 1994. Ipsi- and contralateral commissural growth cones react differently to the cellular environment of the ventral zebrafish spinal cord. J Comp Neurol 350: 122-132.
13. BHIDE PG AND FROST DO. 1999. Intrinsic determinants of retinal axon collateralization and arborization patterns. J Comp Neurol 411: 119-129.
14. BOVOLENTA P AND DODD J. 1990. Guidance of commissural growth cones at the floor plate in embryonic rat spinal cord. Development 109: 435-447.
15. BRADBURY EJ, MOON LDF, POPAT RJ, KING VR, BENNETT GS, PATEL PN, FAWCETT JW AND MCMAHON SB. 2002. Chondroitinase ABC promotes functional recovery after spinal cord injury. Nature 416: 636-640.
16. BRAET F, ROTSCH C, WISSE E AND RADMACHER M. 1998. Comparison of fixed and living liver endothelial cells by atomic force microscopy. Appl Phys A 66: S575-S578.
17. BROSE K AND TESSIER-LAVIGNE M. 2000. Slit proteins: key regulators of axon guidance, axonal branching, and cell migration. Cur Opin Neurobiol 10: 95-102.
18. BRÜMMENDORF T, KENWRICKT S AND RATHJEN FG. 1998. Neural cell recognition molecule L 1: from cell biology to human hereditary brain malformations. Cur Opin Neurobiol 8: 87-97.
19. BULLOCK SL, FLETCHER JM, BEDDINGTON RS AND WILSON VA. 1998. Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase. Genes Dev 12: 1894-1906.
20. BUTT HJ, WOLFF EK, GOULD SA, DIXON NORTHERN B, PETERSON CM AND HANSMA PK. 1990. Imaging cells with the atomic force microscope. J Struct Biol 105: 54-61.
21. CASTELLANI V, CHÉDOTAL A, SCHACHNER M, FAIVRE-SARRAILH C AND ROUGON G. 2000. Analysis of the L1-deficient mouse phenotype reveals cross-talk between Sema3A and L1 signaling pathways in axonal guidance. Neuron 27: 237-249.
22. CHEN H, BAGRI A, ZUPICICH JA, ZOU Y, STOECKLI E, PLEASURE SJ, LOWENSTEIN DH, SKARNES WC, CHEDOTAL A AND TESSIER-LAVIGNE M. 2000. Neuropilin-2 regulates the development of selective cranial and sensory nerves and hippocampal mossy fiber projections. Neuron 25: 43-56.
23. CHITI F, WEBSTER P, TADDEI N, CLARK A, STEFANI M, RAMPONI G, CHRISTOPHER M AND DOBSON CM. 1999. Designing conditions for in vitro formation of amyloid protofilaments and fibrils. Proc Nat Acad Sci USA 96: 3590-3594.
24. CHOI S, JEONG J, KIM T AND PARK S. 1999. Characterization of ephrin-A1 and ephrin-A4 as ligands for the EphAS receptor protein tyrosine kinase. Mol Cells 9: 440-445.
25. CHUNG KY, TAYLOR JS, SHUM DK AND CHAN SO. 2000. Axon routing at the optic chiasm after enzymatic removal of chondroitin sulfate in mouse embryos. Development 127: 2673-2683.
26. CHUNG KY, LEUNG KM, LIN L AND CHAN SO. 2001. Heparan sulfate proteoglycan expression in the optic chiasm of mouse embryos. J Comp Neurol 436: 236-247.
27. COHEN NR, TAYLOR JSH, SCOTT LB, GUILLERY RW, SORIANO P AND FURLEY AJW. 1998. Errors in corticospinal axon guidance in mice lacking the neural cell adhesion molecule L1. Curr Biol 8: 26-33.
28. COLAMARINO SA AND TESSIER-LAVIGNE M. 1995. The axonal chemoattractant Netrin-1 is also a chemorepellent for trochlear motor axons. Cell 81: 621-629.
29. COLLINS VP, BRUNK UT, FREDRIKSSON BA AND WESTERMARK B. 1979. The fine structure of growing human glia and glioma cells. Whole cell preparations. Acta Pathol Microbiol Scand [A] 87: 29-36.
30. DAHME M, BARTSCH U, MARTINI R, ANLIKER B, SCHACHNER M AND MANTEI N. 1997. Disruption of the mouse L1 gene leads to malformations of the nervous system. Nat Genet 17: 346-349.
31. DODD J, MORTON SB, KARAGOGEOS D, YAMAMOTO M AND JESSELL TM. 1988. Spatial regulation of axonal glycoprotein expression on subsets of embryonic spinal neurons. Neuron 1: 105-116.
32. DOTTORI M, HARTLEY L, GALEA M, PAXINOS G, POLIZZOTTO M, KILPATRICK T, BARTLETT PF, MURPHY M, KONTGEN F AND BOYD AW. 1998. EphA4 (Sekl) receptor tyrosine kinase is required for the development of the corticospinal tract. Proc Natl Acad Sci USA. 95: 13248-13253.
33. Dou CJ AND LEVINE JM. 1995. Differential effects of glycosaminoglycans on neunte growth on Iaminin and L1 substrates. J Neurosci 15: 8053-8066.
34. Dow KE AND WANG W. 1998. Cell biology of astrocyte proteoglycans. CMLS. Cell Mol Life Sci 54: 567-581.
35. EASTER SS JR AND SCHMIDT JT. 1977. Reversed visuomotor behavior mediated by induced ipsilateral retinal projections in goldfish. J Neurophysiol 40: 1245-1254.
36. EMERLING DE AND LANDER AD. 1996. Inhibitors and promoters of thalamic neuron adhesion and outgrowth in embryonic neocortex: functional association with chondroitin sulfate. Neuron 17: 1089-1100.
37. ERSKINE L, WILLIAMS SE, BROSE K, KIDD T, RACHEL RA, GOODMAN CS, TESSIER-LAVIGNE M AND MASON CA. 2000. Retinal ganglion cell axon guidance in the mouse optic chiasm: expression and function of robos and slits. J Neurosci 20: 4975-4982.
38. FAISSNER A, CLEMENT A, LOCHTER A, STREIT A, MANDL C AND SCHACHNER M. 1994. Isolation of a neural chondroitin sulfate proteoglycan with neunte outgrowth promoting properties. J Cell Biol 126: 783-799.
39. FAZELI A, DICKINSON SL, HERMISTON ML, TIGHE RV, STEEN RG, SMALL CG, STOECKLI ET ET AL. 1997. Phenotype of mice lacking functional Deleted in Colorectal Carcinoma (DCC) gene. Nature 386: 796-804.
40. FERNAUD-ESPINOSA I, NIETO-SAMPEDRO M AND BovoLENTA P. 1996. Developmental distribution of glycosaminoglycans in embryonic rat brain: Relationship to axonal tract formation. J Neurobiol 30: 410-424.
41. FIDLER PS, SCHUETTE K, ASHER RA, DOBBERTIN A, THORNTON SR, CALLE-PATINO Y, MUIR E, LEVINE JM, GELLER HM, ROGERS JH, FAISSNER A AND FAWCETT JW. 1999. Comparing astrocytic cell lines that are inhibitory or permissive for axon growth: the major axon-inhibitory proteoglycan is NG2. J Neurosci 19: 8778-8788.
42. FITCH MT AND SILVER J. 1997. Glial cell extracellular matrix: boundaries for axon growth in development and regeneration. Cell Tissue Res 290: 379-384.
43. FROST DO, So KF AND SCHNEIDER GE. 1979. Postnatal development of retinal projections in Syrian hamsters: a study using autoradiographic and anterograde degeneration techniques. Neuroscience 4: 1649-1677.
44. GARCIA-ABREU J, MOURA NETO V, CARVALHO SL AND CAVALCANTE LA. 1995a. Regionally specific properties of midbrain glia: I. Interactions with midbrain neurons. J Neurosci Res 40: 471-477.
45. GARCIA-ABREU J, CAVALCANTE LA AND MOURA NETO V. 1995b. Differential patterns of laminin expression in lateral and medial midbrain glia. NeuroReport 6: 761-764.
46. GARCIA-ABREU J, SILVA LCF, TOVAR FF, ONOFRE GR, CAVALCANTE LA AND MOURA NETO V. 1996. Compartmental distribution of sulfated glycosaminoglycans in lateral and medial midbrain astroglial cultures. Glia 17: 339-344.
47. GARCIA-ABREU J, MENDES FA, ONOFRE GR, FREITAS MS, SILVA LCF, MOURA NETO V AND CAVALCANTE LA. 2000. Contribution of heparan sulfate to the non-permissive role of the midline glia to the growth of midbrain neurites. Glia 29: 260-272.
48. GARWOOD J, SCHNADELBACH O, CLEMENT A, SCHUTTE K, BACH A AND FAISSNER A. 1999. DSD-1 proteoglycan is the mouse homolog of phosphacan and displays opposing effects on neurite outgrowth dependent on neuronal lineage. J Neurosci 19: 3888-3899.
49. GEORGE SE, SIMOKAT K, HARDIN J AND CHISHOLM AD. 1998. The VAB-1 Eph receptor tyrosine kinase functions in neural and epithelial morphogenesis in C. elegans. Cell 92: 633-643.
50. HALFTER W, SCHURER B, YIP J, YIP L, TSEN G, LEE JA AND COLE GJ. 1997. Distribution and substrate properties of agrin, a heparan sulfate proteoglycan of developing axonal pathways. J Comp Neurol 383: 1-17.
51. HAMRE KM, KELLER-PECK CR, CAMPBELL RM, PETERSON AC, MULLEN RJ AND GOLDOWITZ D. 1996. Annexin IV is a marker of roof and floor plate development in the murine CNS. J Comp Neurol 368: 527-537.
52. HANTAZ-AMBROISE D, VIGNY M AND KOENIG J. 1987. Heparan sulfate proteoglycan and laminin mediate two different types of neurite outgrowth. J Neurosci 7: 2293-2304.
53. HARROCH A, PALMERI M, ROSENBLUTH J, CUSTER A, OKIGAKI M, SHRAGER P, BLUM M, BUXBAUM JD AND SCHLESSINGER J. 2000. No obvious abnormality in mice deficient in Receptor Protein Tyrosine Phosphatase β. Mol Cell Biol 20: 7706-7715.
54. HARTMANN U AND MAURER P. 2001. Proteoglycans in the nervous system - the quest for functional roles in vivo. Matrix Biology 20: 23-35.
55. HENDERSON E AND SAKAGUCHI D. 1993. Imaging F-Actin in fixed glial cells with a combined optical fluorescence/atomic force microscope. Neuroimage 1: 145-150.
56. HENKE-FAHLE S, BECK KW AND PÜSCHEL A. 2001. Differential responsiveness to the chemorepellent Semaphorin 3A distinguishes ipsi- and contralaterally projecting axons in the chick midbrain. Dev Biol 237: 381-397.
57. HENKEMEYER M, ORIOLI D, HENDERSON JT, SAXTON TM, RODER J, PAWSON T AND KLEIN R. 1996. Nuk controls pathfinding of commissural axons in the mammalian central nervous system. Cell 86: 35-46.
58. HOFFMAN-KIM D, LANDER AD AND JHAVERI S. 1998. Patterns of chondroitin sulfate immunoreactivity in the developing tectum reflect regional differences in glycosaminoglycan biosynthesis. J Neurosci 18: 5881-5890.
59. HOLDER N AND KLEIN R. 1999. Eph receptors and ephrins: effectors of morphogenesis. Development 126: 2033-2044.
60. HOPKER VH, SHEWAN D, TESSIER-LAVIGNE M, POO M AND HOLT C. 1999. Growth-cone attraction to netrin-1 is converted to repulsion by laminin-1. Nature 401: 69-73.
61. HU H. 2001. Cell-surface heparan sulfate is involved in the repulsive guidance activities of Slit2 protein. Nature Neurosci. 4: 695-701.
62. ICHIJO H AND KAWABATA I. 2001. Roles of the telencephalic cells and their chondroitin sulfate proteoglycans in delimiting an anterior border of the retinal pathway. J Neurosci 21: 9304-9314.
63. IMONDI R AND KAPRIELIAN Z. 2001. Commissural axon pathfinding on the contralateral side of the floorplate: a role for B-class ephrins in specifying the dorsoventral position of longitudinally projecting commissural axons. Development 128: 4859-4871.
64. IMONDI R, WIDEMAN C AND KAPRIELIAN Z. 2000. Complementary expression of transmembrane ephrins and their receptors in the mouse spinal cord: a possible role in constraining the orientation of longitudinally projecting axons. Development 127: 1397-1410.
65. IOZZO RV. 1998. Matrix proteoglycans: From molecular design to cellular function. Annu Rev Biochem 67: 609-652.
66. IRIE A, YATES EA, TURNBULL JE AND HOLT CE. 2002. Specific heparan sulfate structures involved in retinal axon targeting. Development 129: 61-70.
67. JHAVERI S. 1993. Midline glia of the tectum: abarrier for developing retinal axons. Perspect Dev Neurobiol 1: 237-243.
68. JHAVERI S AND HOFFMAN-KIM D. 1996. Unilateral containment of retinal axons by tectal glia: a possible role for sulfated proteoglycans. Prog Brain Res 108: 136-148.
69. JHAVERI S, EDWARDS MA AND SCHNEIDER GE. 1991. Initial stages of retinofugal axon development in the hamster: evidence for two distinct modes of growth. Exp Brain Res 87: 371-382.
70. KAGEYAMA GH AND ROBERTSON RT. 1993. Transcellular retrograde labeling of radial glial cells with WGA-HRP and DiI in neonatal rat and hamster. Glia 9: 70-81.
71. KAHANE N AND KALCHEIM C. 1998. Identification of early postmitotic cells in distinct embryonic sites and their possible roles in morphogenesis. Cell Tissue Res 294: 297-307.
72. KALIL K, SZEBENYI G AND DENT EW. 2000. Common mechanisms underlying growth cone guidance and axon branching. J Neurobiol 44: 145-158.
73. KAMIGUCHI H, HLAVIN ML AND LEMMON V. 1998. Role of L1 in Neural Development: What the Knockouts Tell Us. Mol Cell Neurosci 12: 48-55.
74. KAPPLER J, FRANKEN S, JUNGHANS U, HOFFMANN R, LINKE T, MULLER HW AND KOCH KW. 2000. Glycosaminoglycan-binding properties and secondary structure of the C-terminus of netrin-1. Biochem Biophys Res Commun 271: 287-291.
75. KAPRIELIAN Z, RUNKO E AND IMONDI R. 2001. Axon guidance at the midline choice point. Dev Dyn 221: 154-181.
76. KINGSBURY BF. 1930. The developmental significance of the floor plate of the brain and spinal chord. J Comp Neurol 50: 177-207.
77. KNOLL B AND DRESCHER U. 2002. Ephrin-As as receptors in topographic projections. Trends Neurosci 25: 145-149.
78. KULLANDER K, CROLL SD, ZIMMER M, PAN L, MCCLAIN J, HUGHES V, ZABSKI S, DECHIARA TM, KLEIN R, YANCOPOULOS GD AND GALE NW. 2001. Ephrin-B3 is the midline barrier that prevents corticospinal tract axons from recrossing, allowing for unilateral motor control. Genes Dev 15: 877-888.
79. KURT MA, DAVIES DC AND KIDD M. 1999. βeta-Amyloid immunoreactivity in astrocytes in Alzheimer's disease brain biopsies: an electron microscope study. Exp Neurol 158: 221-228.
80. KUYPERS HGJM. 1981. Motor control. In BROOKHART JM AND MOUNTCASTLE VB (eds.), Handbook of Physiology, Section 1: The Nervous System, Bethesda: American Physiological Society.
81. LANDER AD. 1993. Proteoglycans in the nervous system. Curr Opin Neurobiol 3: 716-723.
82. LANDER A, NAKATO H, SELLECK SB, TURNBULL JE AND COATH C. 1999. Cell surface proteoglycans in signaling and development, HFSP, Strasbourg, 215 pp.
83. LEFRANÇOIS T, FAGES C, PESCHANSKI M AND TARDY M. 1997. Neuritic outgrowth associated with astroglial phenotypic changes induced by anti-sense Glial Fibrillary Acidic Protein (GFAP) mRNA in injured neuron-astrocyte cocultures. J Neurosci 17: 4121-4128.
84. LIANG Y, ANNAN RS, CARR SA, POPP S, MEVISSEN M, MARGOLIS RK AND MARGOLIS RU. 1999. Mammalian homologues of the Drosophila slit protein are ligands of the heparan sulfate proteoglycan glypican-1 in brain. J Biol Chem 274: 17885-17892.
85. LIESI P AND SILVER J. 1988. Is astrocyte laminin involved in axon guidance in the mammalian CNS? Dev Biol 130: 774-785.
86. LIN X AND PERRIMON N. 1999. Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signalling. Nature 400: 281-284.
87. LIN X, BUFF EM, PERRIMON N AND MICHELSON AM. 1999. Heparan sulfate proteoglycans are essential for FGF receptor signaling during Drosophila embryonic development. Development 126: 3715-3723.
88. LITWACK ED, STIPP CS, KUMBASAR A AND LANDER AD. 1994. Neuronal expression of glypican, a cell-surface glycosylphosphatidylinositol-anchored heparan sulfate proteoglycan, in the adult rat nervous system. J Neurosci 14: 3713-3724.
89. LIU D, SHRIVER Z, VENKATARAMAN G, EL SHABRAWI Y AND SASISEKHARAN R. 2002. Tumor cell surface heparan sulfate as cryptic promoters or inhibitors of tumor growth and metastasis. Proc Natl Acad Sci USA 99: 568-573.
90. LUCKENBILL-EDDS L. 1997. Laminin and the mechanism of neuronal outgrowth. Brain Res Rev 23: 1-27.
91. LUSTIG M, ERSKINE L, MASON CA, GRUMET M AND SAKURAI T. 2001. Nr-CAM expression in the developing mouse nervous system: ventral midline structures, specific fiber tracts, and neuropilar regions. J Comp Neurol 434: 13-28.
92. MARCUS RC AND MASON CA. 1995. The first retinal axon growth in the mouse optic chiasm: Axon patterning and the cellular environment. J Neurosci 15: 6389-6402.
93. MARCUS RC, BLAZESKI R, GODEMENT P AND MASON CA. 1995. Retinal axon divergence in the optic chiasm: uncrossed axons diverge from crossed axons within a midline glial specialization. J Neurosci 15: 3716-3729.
94. MARCUS RC, MATHEWS GA, GALE NW, YANCOPOULOS GD AND MASON. 2000. Axon guidance in the mouse optic chiasm: Retinal neunte inhibition by ephrin " A"-expressing hypothalamic cells in vitro. Dev Biol 221: 132-147.
95. MASON CA AND SRETAVAN DW. 1997. Glia, neurons, and axon pathfinding during optic chiasm development. Curr Opin Neurobiol 7: 647-653.
96. MAUREL P, RAUCH U, FLAD M, MARGOLIS RK AND MARGOLIS RU. 1994. Phosphacan, a chondroitin sulfate proteoglycan of brain that interacts with neurons and neural cell-adhesion molecules, is an extracellular variant of a receptor-type protein tyrosine phosphatase. Proc Natl Acad Sci U S A 91: 2512-2516.
97. MCCABE CF AND COLE GJ. 1992. Expression of the barrier-associated proteins EAP-300 and claustrin in the developing nervous system. Dev Brain Res 70: 9-24.
98. MENDES F, ONOFRE C, SILVA LC, CAVALCANTE LA AND GARCIA-ABREU J. 2002. The concentration-dependent actions of glial chondroitin sulfate on the neuritic growth of midbrain neurons. Submitted.
99. MENDEZ-OTERO R AND SANTIAGO MF. 2001. Functional role of a glycolipid in directional movements of neurons. An Acad Bras Cienc 73: 221-229.
100. MENDEZ-OTERO R, CAVALCANTE LA, ROCHA-MIRANDA CE, BERNARDES RF AND BARRADAS PC. 1985. Growth and restriction of the ipsilateral retinocollicular projection in the opossum. Dev Brain Res 18: 199-210.
101. MEYER-PUTTLITZ B, JUNKER E, MARGOLIS RU AND MARGOLIS RK. 1996. Chondroitin sulfate proteoglycans in the developing central nervous system. II. Immunocytochemical localization of neurocan and phosphacan. J Comp Neurol 366: 44-54.
102. MILEV P, FRIEDLANDER DR, SAKURAI T, KARTHIKEYAN L, FLAD M, MARGOLIS RK, GRUMET M AND MARGOLIS RU. 1994. Interactions of the chondroitin sulfate proteoglycan phosphacan, the extracellular domain of a receptor-type protein tyrosine phosphatase, with neurons, glia, and neural cell adhesion molecules. J Cell Biol 127: 1703-1715.
103. MILEV P, MAUREL P, HARING M, MARGOLIS RK AND MARGOLIS RU. 1996. TAG-1/axonin-1 is a high-affinity ligand of neurocan, phosphacan/proteintyrosine phosphatase-ξ /β, and N-CAM. J Biol Chem 271: 15716-15723.
104. MING G-L, SONG H-J, BERNINGER B, HOLT CE, TESSIER-LAVIGNE M AND Poo M-M. 1997. cAMP-dependent growth cone guidance by Netrin-1. Neuron 19: 1225-1235.
105. MOON LGF, ASHER RA, RHODES KE AND FAWCETT JW. 2001. Regeneration of CNS axons back to their target following treatment of adult rat brain with chonddoitinase ABC. Nat Neurosci 4: 465-466.
106. MORI K, IKEDA J AND HAYAISHI O. 1990. Monoclonal antibody R2D5 reveals midsagittal radial glial system in postnatally developing and adult brainstem. Proc Natl Acad Sci USA 87: 5489-5493.
107. NAKAGAWA S, BRENNAN C, JOHNSON KG, SHEWAN D, HARRIS WA AND HOLT CE. 2000. Ephrin-B regulates the Ipsilateral routing of retinal axons at the optic chiasm. Neuron 25: 599-610.
108. NIEDERÖST BP, ZIMMERMANN DR, SCHWAB ME AND BANDTLOW CE. 1999. Bovine CNS myelin contains neurite growth-inhibitory activity associated with chondroitin sulfate proteoglycans. J Neurosci 19: 8979-8989.
109. ONOFRE GR, WERNECK CC, MENDES FA, GARCIA-ABREU J, MOURA NETO V, CAVALCANTE LA AND SILVA LCF. 2001. Astroglial cells derived from lateral and medial midbrain sectors differ in their synthesis and secretion of sulfated glycosaminoglycans. Braz J Med Biol Res 34: 251-258.
110. OOHIRA A, MATSUI F, TOKITA Y, YAMAUCHI S AND AONO S. 2000. Molecular interactions of neural chondroitin sulfate proteoglycans in the brain development. Arch Biochem Biophys 374: 24-34.
111. ORIOLI D AND KLEIN R. 1997. The Eph receptor family: axonal guidance by contact repulsion. Trends Genet 13: 354-359.
112. ORIOLI D, HENKEMEYER M, LEMKE G, KLEIN R AND PAWSON T. 1996. Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation. EMBO J 15: 6035-6049.
113. ORLINO EN JR, WONG CM AND PHELPS PE. 2000. L1 and GAD65 are expressed on dorsal commissural axons in embryonic rat spinal cord. Dev Brain Res 125: 117-130.
114. PARK S, FRISEN J AND BARBACID M. 1997. Aberrant axonal projections in mice lacking EphA8 (Eek) tyrosine protein kinase receptors. EMBO J 16: 3106-3114.
115. PARPURA V, HAYDON PG AND HENDERSON E. 1993. Three-dimensional imaging of living neurons and glia with the atomic force microscopy. J Cell Sci 104:427-432.
116. PIEPKORN M, HOVINGH P, BENNETT KL AND LINKER A. 1999. Heparan sulfate composition of alternatively spliced CD44 fusion proteins. Biochem Biophys Res Commun 257: 839-842.
117. PIRES-NETO MA, BRAGA-DE-SOUZA S AND LENT R. 1998. Molecular tunnels and boundaries for growing axons in the anterior commissure of hamster embryos. J Comp Neurol 399: 176-188.
118. PLUMP AS, ERSKINE E, SABATIER C, BROSE K, EPSTEIN CJ, GOODMAN CS, MASON CA AND TESSIER-LAVIGNE M. 2002. Slitl and slit2 cooperate to prevent premature midline crossing of retinal axons in the mouse visual system. Neuron 33: 219-232.
119. POSTUMA RB, HE W, NUNAN J, BEYREUTHER K, MASTERS CL, BARROW CJ AND SMALL DH. 2000. β-amyloid peptides inhibit cell adhesion and neurite outgrowth in primary neuronal cultures. J Neurochem 74: 1122-1130.
120. PUELLES L. 1995. A segmental morphological paradigm for understanding vertebrate forebrains. Brain Behav Evol 46: 319-337.
121. RADMACHER M, TILLMAN RW, FRITZ M AND GAUB HE. 1992. From molecules to cells: imaging of soft samples with the atomic force microscope. Science 257: 1900-1905.
122. RAEDLER E, RAEDLER A AND FELDHAUS S. 1981. Prenatal differentiation of colliculus superior in the rat. Bibl Anat 19: 174-191.
123. RAPER JA. 2000. Semaphorins and their receptors in vertebrates and invertebrates. Curr Opin Neurobiol 10: 88-94.
124. RIOPELLE RJ AND Dow KE. 1990. Functional interaction of neuronal heparan sulphate proteoglycans with laminin. Brain Res 525: 92-100.
125. RONCA F, ANDERSEN JS, PAECH V AND MARGOLIS RU. 2001. Characterization of Slit protein interactions with glypican-1. J Biol Chem 276: 29141-29147.
126. SAKURAI T, LUSTIG M, NATIV M, HEMPERLY JJ, SCHLESSINGER J, PELES E AND GRUMET M. 1997. Induction of neurite outgrowth through Contactin and Nr-CAM by extracellular regions of glial Receptor Tyrosine Phosphatase β. J Cell Biol 136: 907-918.
127. SANDERSON RD AND LANDER A. 1999. Relationships between structure and function of syndecans and glypicans. In LANDER A, NAKATO H, SELLECK SB, TURNBULL JE AND COATH C (eds.) Cell surface proteoglycans in signaling and development, HFSP, Strasbourg, pp. 103-112.
128. SANTIAGO MF, BERREDO-PINHO M, GANDRA M, COSTA MR, CAVALCANTE LA AND MENDEZ-OTERO R. 2001. Expression and function of ganglioside 9-O-acetyl GD3 in post-mitotic granule cell development. Mol Cell Neurosci 17: 488-499.
129. SCULLY AL, MCKEOWN M AND THOMAS JB. 1999. Isolation and characterization of Dek, a Drosophila Eph receptor protein tyrosine kinase. Mol Cell Neurosci 13: 337-347.
130. SHIGA T, OPPENHEIM RW, GRUMET M AND EDELMAN GM. 1990. Neuron-glia cell adhesion molecule (Ng-CAM) expression in the chick embryo spinal cord: observations on the earliest developing intersegmen-tal interneurons. Dev Brain Res 55: 209-217.
131. SMITH VL. 1983. The development and postnatal organization of primary afferent projections to the rat thoracic spinal cord. J Comp Neurol 220: 29-43.
132. SNOW AD, SEKIGUCHI R, NOCHLIN D, FRASER P, KIMATA K, MIZUTANI A, ARAI M, SCHREIER WA AND MORGAN DG. 1994. An important role of heparan sulfate proteoglycan (Perlecan) in a model system for the deposition and persistence of fibrillar A beta-amyloid in rat brain. Neuron 12: 219-234.
133. SNOW DM, STEINDLER DA AND SILVER J. 1990a. Molecular and cellular characterization of the glial roof plate of the spinal cord and optic tectum: a possible role for a proteoglycan in the development of an axon barrier. Dev Biol 138: 359-376.
134. SNOW DM, LEMMON V, CARRINO DA, CAPLAN AI AND SILVER J. 1990b. Sulfated proteoglycans in astroglial barriers inhibit neurite outgrowth in vitro. Exp Neurol 109: 111-130.
135. SNOW DM, BROWN EM AND LETOURNEAU PC. 1996. Growth cone behavior in the presence of soluble chondroitin sulfate proteoglycan (CSPG), compared to behavior on CSPG bound to laminin or fibronectin. Int J Dev Neurosci 14: 331-349.
136. SOMMER L, RAO M AND ANDERSON DJ. 1997. RPTPδ and the novel protein tyrosine phosphatase RPTPψ are expressed in restricted regions of the developing central nervous system. Dev Dyn 208: 48-61.
137. SRETAVAN DW, FENG L, PURE E AND REICHARDT LF. 1994. Embryonic neurons of the developing optic chiasm express L1 and CD44, cell surface molecules with opposing effects on retinal axon growth. Neuron 12: 957-975.
138. STOKER AW. 2001. Receptor tyrosine phosphatases in axon growth and guidance. Curr Opin Neurobiol 11; 95-102.
139. SUGA H, KOYANAGI M, HOSHIYAMA D, ONO K, IWABE N, KUMA K AND MIYATA T. 1999. Extensive gene duplication in the early evolution of animals before the parazoan-eumetazoan split demonstrated by G proteins and protein tyrosine kinases from sponge and hydra. J Mol Evol 48: 646-653.
140. SUN Q, BAHRI S, SCHMID A, CHIA W AND ZINN K. 2000. Receptor tyrosine phosphatases regulate axon guidance across the midline of the Drosophila embryo. Development 127: 801-812.
141. TALTS JF, ANDAC Z, GÖHRING W, BRANCACCIO A AND TIMPL R. 1999. Binding of the G domains of laminin α1 and α2 chains and perlecan to heparin, sulfatides, α-dystroglycan and several extracellular matrix proteins. EMBO J 18: 863-870.
142. TAMADA A, SHIRASAKl R AND MURAKAMl F. 1995. Floor plate chemoattracts crossed axons and chemorepels uncrossed axons in the vertebrate brain. Neuron 14: 1083-1093.
143. TAMAGNONE L AND COMOGLIO PM. 2000. Signalling by semaphorin receptors: cell guidance and beyond. Trends Cell Biol 10: 377-383.
144. TARDY M. 2002. Role of laminin bioavailability in the astroglial permissivity for neuritic outgrowth. An Acad Bras Cienc 74: 683-690.
145. TESSIER-LAVIGNE M AND GOODMAN CS. 1996. The molecular biology of axon guidance. Science 274: 1123-1133.
146. TIMPL R, RODDE H, ROBEY PG, RENNARD SI, FOIDART J-M AND MARTIN GR. 1979. Laminin: a glycoprotein from basement membrane. J Biol Chem 254: 9933-9937.
147. TOBEY SL, MCCLELLAND KJ AND CULP LA. 1985. Neunte extension by neuroblastoma cells on substratumbound fibronectin's cell-binding fragment but not on the heparan sulfate-binding protein, platelet factor-4. Exp Cell Res 158: 395-412.
148. TOIKKA J, AALTO J, HAYRINEN J, PELLINIEMI LJ AND FINNE J. 1998. The polysialic acid units of the neural cell adhesion molecule N-CAM form filament bundle networks. J Biol Chem 273: 28557-28559.
149. TRAN TS AND PHELPS PE. 2000. Axons crossing in the ventral commissure express L1 and GAD65 in the developing rat spinal cord. Dev Neurosci 22: 228-236.
150. TURNBULL J, POWELL A AND GUIMOND S. 2001. Heparan sulfate: decoding a dynamic multifunctional cell regulator. Trends Cell Biol 11: 75-82.
151. VAN HARTESVELDT C, MOORE B AND HARTMAN BK. 1986. Transient midline raphe glial structure in the developing rat. J Comp Neurol 253:175-184.
152. VAN HORSSEN J, WILHELMUS MM, HELJASVAARA R, PIHLAJANIEMI T, WESSELING P, DE WAAL RM AND VERBEEK MM. 2002. Collagen XVIII: a novel heparan sulfate proteoglycan associated with vascular amyloid depositions and senile plaques in Alzheimer's disease brains. Brain Pathol 12: 456-462.
153. VARELA-ECHAVARRIA A, TUCKER A, PUSCHEL AW AND GUTHRIE S. 1997. Motor axon subpopulations respond differentially to the chemorepellents netrin-1 and semaphorin D. Neuron 18: 193-207.
154. VERBEEK MM, OTTE-HÖLLER I, VAN DEN BORN J, VAN DEN HEUVEL LPWJ, DAVID G, WESSELING P AND DE WAAL RMW. 1999. Agrin is a major heparan sulfate proteoglycan accumulating in Alzheimer's disease brain. Am J Pathol 155: 2115-2125.
155. VERNA JM, FICHARD A AND SAXOD R. 1989. Influence of glycosaminoglycans on neunte morphology and outgrowth patterns in vitro. Int J Dev Neurosci 7: 389-399.
156. WALZ A, MCFARLANE S, BRICKMAN YG, NURCOMBE V, BARTLETT PF AND HOLT CE. 1997. Essential role of heparan sulfates in axon navigation and targeting in the developing visual system. Development 124: 2421-2430.
157. WANG LC, DANI J, GODEMENT P, MARCUS RC AND MASON CA. 1995. Crossed and uncrossed retinal axons respond differently to cells of the optic chiasm midline in vitro. Neuron 15: 1349-1364.
158. WEISSMÜLLER G, GARCIA-ABREU J, BISCH PM, MOURA NETO V AND CAVALCANTE LA. 2000. Glial cells with differential neunte growth-modulating properties probed by atomic force microscopy. Neurosci Res 38: 217-220.
159. WEYN B, KALLE W, KUMAR-SINGH S, VAN MARCK E, TANKE H AND JACOB W. 1998. Atomic force microscopy: influence of air drying and fixation on the morphology and viscoelasticity of cultured cells. J Microsc 189(Pt2): 172-180.
160. WINKLER S, STAHL RC, CAREY DJ AND BANSAL R. 2002. Syndecan-3 and perlecan are differentially expressed by progenitors and mature oligodendrocytes and accumulate in the extracellular matrix. J Neurosci Res 69: 477-487.
161. Wu D-Y, JHAVERI S AND SCHNEIDER GE. 1995. Glial environment in the developing superior colliculus of hamsters in relation to the timing of retinal axon ingrowth. J Comp Neurol 358: 206-218.
162. YAMAGUCHI Y. 2001. Heparan sulfate proteoglycans in the nervous system: their diverse roles in neurogenesis, axon guidance, and synaptogenesis. Semin Cell Dev Biol 12: 99-106.
163. YAMANE Y, TOHNO-OKA R, YAMADA S, FURUYA S, SHIOKAWA K, HIRABAYASHI Y, SUGINO H AND SUGAHARA K. 1998. Molecular characterization of Xenopus embryo heparan sulfate. Differential structural requirements for the specific binding to basic fibroblast growth factor and follistatin. J Biol Chem 273: 7375-7381.
164. YULIS CR, MOTA MD, ANDRADES JA, RODRIGUEZ S, PERUZZO B, MANCERA JM, RAMIREZ P, GARRIDO M, PEREZ-FIGAREZ JM, FERNANDEZ-LLEBREZ P AND RODRIGUEZ EM. 1998. Floor plate and the subcommissural organ are the source of secretory compounds of related nature: comparative immunocytochemical study. J Comp Neurol 392: 19-34.
165. YURCHENCO PD, TSILIBARY EC, CHARONIS AS AND FURTHMAYR H. 1985. Laminin polymerization in vitro. Evidence for a two-step assembly with domain specificity. J Biol Chem 260: 7636-7644.
166. YURCHENCO PD, CHENG YS AND RUBEN GC. 1987. Self-assembly of a high molecular weight basement membrane heparan sulfate proteoglycan into dimers and oligomers. J Biol Chem 262: 17668-17676.
167. YURCHENCO PD, CHENG Y-S AND SCHITTNY JC. 1990. Heparin modulation of laminin polymerization. J Biol Chem 265: 3981-3991.
168. ZHOU FC. 1990. Four patterns of laminin-immunoreactive structure in developing rat brain. Brain Res Dev Brain Res 55: 191-201.
169. ZHOU XH, BRAKEBUSCH C, MATTHIES H, OOHASHI T, HIRSCH E, MOSER M, KRUG M, SEIDENBECHER CI, BOECKERS TM, RAUCH U, BUETTNER R, GUNDELHNGER ED AND FASSLER R. 2001. Neurocan is dispensable for brain development. Mol Cell Biol 21: 5970-5978.
170. Zou Y, STOECKLI E, CHEN H AND TESSIER-LAVIGNE M. 2000. Squeezing axons out of the gray matter: a role for slit and semaphorin proteins from midline and ventral spinal cord. Cell 102: 363-375.