Synthesis and in vitro and in vivo evaluation of [11C]methyl-BIII277CL for imaging the PCP-binding site of the nmda receptor by PET

Journal of Receptors and Signal Transduction

Volumn 22, Issue 1-4, 2002, Pages 123-139

  Kokic, Marko ^a   Honer, Michael ^a   Kessler, Lea J ^a   Grauert, Matthias ^b   Schubiger, Pius A ^a   Ametamey, Simon M ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

11C Methyl BIII277CL; Carbon 11; NMDA receptor; PET

Indexed keywords

BENZOMORPHAN DERIVATIVE; BIII 277CL; CARBON 11; METHYL BIII 277CL; METHYL IODIDE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PHENCYCLIDINE; TRACER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; BINDING AFFINITY; BINDING SITE; CONCENTRATION (PARAMETERS); CONFERENCE PAPER; DRUG DISTRIBUTION; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NEUROPROTECTION; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RAT;

ANIMALS; BENZOMORPHANS; BINDING SITES; BRAIN; CARBON RADIOISOTOPES; FEMALE; LIGANDS; MALE; MICE; PHENCYCLIDINE; RADIOLIGAND ASSAY; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; SWINE; SYNAPTIC MEMBRANES; TOMOGRAPHY, EMISSION-COMPUTED;

ANIMALIA; EOS; SUS SCROFA;

EID: 0036978640     PISSN: 10799893     EISSN: 15324281     Source Type: Journal    
DOI: 10.1081/RRS-120014591     Document Type: Conference Paper

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