Molecular and pharmacological characterisation of the MSH-R alleles in Swiss cattle breeds

Journal of Receptors and Signal Transduction

Volumn 22, Issue 1-4, 2002, Pages 421-430

  Graphodatskaya, D ^a   Joerg, H ^a   Stranzinger, G ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

Cattle; Coat colour; Cyclic AMP; MSH R; Polymorphism

Indexed keywords

ADENYLATE CYCLASE; ALPHA INTERMEDIN; CYCLIC AMP; EUMELANIN; HORMONE RECEPTOR; MELANIN; MELANOCYTE STIMULATING HORMONE RECEPTOR; MONOPHENOL MONOOXYGENASE; UNCLASSIFIED DRUG;

ALLELE; BREED; CATTLE; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONFERENCE PAPER; ENZYME ACTIVATION; GENETIC TRANSFECTION; HEREDITY; HORMONE SYNTHESIS; HUMAN; HUMAN CELL; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; RECEPTOR UPREGULATION;

ALLELES; ALPHA-MSH; AMINO ACID SEQUENCE; ANIMALS; BREEDING; CATTLE; CELLS, CULTURED; CLONING, MOLECULAR; CYCLIC AMP; GENES, DOMINANT; GENES, RECESSIVE; GENETIC VECTORS; HAIR COLOR; HUMANS; MOLECULAR SEQUENCE DATA; RECEPTORS, PITUITARY HORMONE; SEQUENCE HOMOLOGY, AMINO ACID; SKIN PIGMENTATION; TRANSFECTION;

BOS TAURUS; MAMMALIA; VECTORS;

EID: 0036975995     PISSN: 10799893     EISSN: 15324281     Source Type: Journal    
DOI: 10.1081/RRS-120014611     Document Type: Conference Paper

References (14)

1. Searle, A.G. Coat Colour and It's Production. In Comparative Genetics of Coat Colour in Mammals; Waddington, C.H., Hey, D.H., Cadogan, J.I.G., Tristram, G.R., Massey, H., Willmore, A.P., Bondi, H., Hirsch, K.A., Green, S.L., Eds.; Logos Press: London, 1968;40-55.
2. Searle, A.G. Coat Colour Genes Their Action and Their Allelomorphs. In Comparative Genetics of Coat Colour in Mammals; Waddington, C.H., Hey, D.H., Cadogan, J.I.G., Tristram, G.R., Massey, H., Willmore, A.P., Bondi, H., Hirsch, K.A., Green, S.L., Eds.; Logos Press: London, 1968; 55-74.
3. Jackson, I.J. Homologous Pigmentation Mutation in Humans, Mouse and Other Model Organisms. Hum. Mol. Genet. 1997, 6, 1613-1624.
4. Robbins, L.S.; Nadeau, J.H.; Johnson, K.R.; Kelly, M.A.; Roselli-Rehfuss, L.; Baack, E.; Mountjoy, K.G.; Cone, R.D. Pigmentation Phenotypes of Variant Extension Locus Alleles Result from Point Mutations that Alter MSH Receptor Function. Cell 1993, 72, 827-834.
5. Fimia, G.M.; Sassone-Corsi, P. Cyclic AMP Signalling. J. Cell Sci. 2001, 114, 1971-1972.
6. Mountjoy, K.G.; Robbins, L.S.; Morturd, M.T.; Cone, R.D. The Cloning of a Family of Genes that Encode the Melanocortin Receptor. Science 1992, 257, 1248-1251.
7. Cone, R.D.; Lu, D.; Koppula, S.; Vage, D.I.; Klungland, H.; Boston, B.; Chen, W.; Orth, D.N.; Pouton, C.; Kesterson, R.A. The Melanocortin Receptors: Agonist, Antagonists, and the Hormonal Control of Pigmentation. Rec. Progr. Horm. Res. 1996, 51, 287-318.
8. Lu, D.; Willard, D.; Patel, I.R.; Kadwell, S.; Overton, L.; Kost, T.; Luther, M.; Chen, W.; Woychik, R.P.; Wilkinson, W.O. Agouti Protein is an Antogonist of the Melanocyte-Stimulating-Hormone Receptor. Nature 1994, 371, 799-802.
9. Klungland, H.; Vage, D.I.; Gomez-Raya, L.; Adalsteinson, S.; Lien, S. The Role of Melanocyte-Stimulating Hormone Receptor in Bovine Coat Colour Determination. Mamm. Genome 1995, 6, 636-639.
10. Klungland, H.; Olsen, H.G.; Hassanane, M.S.; Mahrous, K.; Vage, D.I. Coat Colour Genes in Diversity Studies. J. Anim. Breed. Genet. 2000, 117, 217-224.
11. Joerg, H.; Fries, H.R.; Meijerink, E.; Stranzinger, G.F. Red Coat Colour in Holstein Cattle is Associated with a Deletion in the MSHR Gene. Mamm. Genome. 1996, 7, 317-318.
12. Devereux, J.; Haeberli, P.; Smithies, O. A Comprehensive Set of Sequence Analysis Programs for the Vax. Nucl. Acids Res. 1984, 12, 387-395.
13. Frandberg, P.A.; Doufexis, M.; Kapas, S.; Chhajlani, V. Amino Acid Residues in Third Intracellular Loop of Melanocortin 1 Receptor are Involved in G-Protein Coupling. Biochem. Mol. Biol. Int. 1998, 46, 913-922.
14. Kriegesmann, B.; Dierkes, B.; Leeb, T.; Jansen, S.; Brenig,ss B. Two Breed-Specific Bovine MC1-R Alleles in Brown Swiss and Saler Breeds. J. Dairy Sci. 2001, 84, 1768-1771.