Effects of imipramine on T cell subsets in olfactory bulbectomized mice

Neuropsychobiology

Volumn 46, Issue 4, 2002, Pages 194-196

  Komori, T ^a   Yamamoto, M ^a   Matsumoto, T ^a   Zhang, K ^a   Okazaki, Y ^a  

^a MIE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Antidepressants; Imipramine; L3T4 positive T cell; Lyt2 positive T cell; Neuroimmunomodulation; Olfactory bulbectomy; T cell subsets

Indexed keywords

ANTIDEPRESSANT AGENT; IMIPRAMINE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; HELPER CELL; IMMUNE SYSTEM; IMMUNOSUPPRESSIVE TREATMENT; MALE; MOUSE; NEUROIMMUNOLOGY; NONHUMAN; OLFACTORY BULBECTOMY; PRIORITY JOURNAL; SUPPRESSOR CELL; T LYMPHOCYTE SUBPOPULATION;

ANIMALS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; DEPRESSIVE DISORDER; DISEASE MODELS, ANIMAL; HUMANS; IMIPRAMINE; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; NEUROIMMUNOMODULATION; OLFACTORY BULB; T-LYMPHOCYTE SUBSETS;

EID: 0036974948     PISSN: 0302282X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000067811     Document Type: Article

References (21)

1. Irwin M: Immune correlates of depression. Adv Exp Med Biol 1999;46:1-24.
2. Weizman R, Laor N, Podliszewski E, Notti I, Djaldetti M, Bessler H: Cytokine production in major depressed patients before and after clomipramine treatment. Biol Psychiatry 1994;35:42-47.
3. Sluzewska A, Rybakowski JK, Laciak M, Mackiewicz A, Sobieska M, Wiktorowicz K: Interleukin-6 serum levels in depressed patients before and after treatment with fluoxetine. Ann NY Acad Sci 1995;762:474-477.
4. Seidel A, Arolt V, Hunstiger M, Rink L, Behnisch A, Kirchner H: Major depressive disorder is associated with elevated monocyte counts. Acta Psychiatr Scand 1996;94:198-204.
5. Frank MG, Hendricks SE, Johnson DR, Wieseler JL, Burke WJ: Antidepressants augment natural killer cell activity: In vivo and in vitro. Neuropsychobiology 1999;39:18-24.
6. Audus KL, Gordon MA: Tricyclic antidepressant effects on the murine lymphocyte mitogen response. J Immunopharmacol 1982;4:13-27.
7. Descotes J, Tedone R, Evreux JC: Different effects of psychotropic drugs on delayed hypersensitivity responses in mice. J Neuroimmunol 1985;9:81-85.
8. Miller AH, Lackner C: Tricyclic antidepressants and immunity; in Miller AH (ed): Depressive Disorders and Immunity. Washington, American Psychiatric Press, 1989, pp 85-103.
9. Eisen JN, Irwin J, Quary J, Livnat S: The effect of antidepressants on immune function in mice. Biol Psychiatry 1989;26:805-817.
10. Bianchi M, Sacerdote P, Panerai AE: Fluoxetine reduces inflammatory edema in the rat: Involvement of the pituitary-adrenal axis. Eur J Pharmacol 1994;263:81-84.
11. Bianchi M, Rossoni G, Sacerdote P, Panerai AE, Berti F: Effects of chlomipramine and fluoxetine on subcutaneous carrageenin-induced inflammation in the rat. Inflamm Res 1995;44:466-469.
12. Jesberger JA, Richardson JS: Animal models of depression: Parallels and correlates to severe depression in humans. Biol Psychiatry 1985;20:764-784.
13. Kelly JP, Wrynn AS, Leonard BE: The olfactory bulbectomized rat as a model of depression: An update. Pharmacol Ther 1997;74:299-316.
14. Van Riesen, Leonard BE: Effects of psychotropic drugs on the behaviour and neurochemistry of olfactory bulbectomized rats; in File S (ed): Psychopharmacology of Anxiolytics and Antidepressants. New York, Pergamon Press, 1991, pp 231-250.
15. Komori T, Fujiwara R, Nomura J, Yokoyama MM: Effects of restraint stress on plaque-forming cell response in normal and olfactory bulbectomized mice. Biol Psychiatry 1991;29:695-698.
16. O'Neill B, O'Connor WT, Leonhard BE: Depressed neutrophil phagocytosis in the rat following olfactory bulbectomy reversed by chronic desipramine treatment. Med Sci Res 1987;15:267-268.
17. Song C, Leonhard BE: Serotonin reuptake inhibitors reverse the impairments in behaviour, neurotransmitter and immune functions in the olfactory bulbectomized rat. Hum Psychopharm Clin 1994;9:135-146.
18. Song C, Leonhard BE: An acute phase protein response in the olfactory bulbectomized rat: Effect of sertraline treatment. Med Sci Res 1994;22:313-314.
19. Song C, Leonhard BE: Changes in behaviour, neurotransmitter and neutrophil function in olfactory bulbectomized rats; effect of desipramine treatment (abstract 21). 2nd Int Neuroimmunomodul Congr, Paestum, 1993.
20. Song C, Kelly PJ, Earley B, Leonhard BE: Behaviour, lymphocyte activity and serum corticosterone level in olfactory bulbectomized rats following chronic desipramine treatment. Ir J Med Sci 1993;162:386-387.
21. Connor TJ, Harkin A, Kelly JP, Leonhard BE: Olfactory bulbectomy provokes a suppression of interleukin-1β and tumor necrosis factor-α production in response to an in vivo challenge with lipopolysaccharide: Effect of chronic desipramine treatment. Neuroimmunomodulation 2000;7:27-35.