Cyclosporine or FK506 decrease mature epidermal growth factor protein expression and renal tubular regeneration in rat kidneys with ischemia/reperfusion injury

Nephron

Volumn 92, Issue 4, 2002, Pages 914-921

  Yang, Chul Woo ^a   Lee, Seung Hun ^a   Lim, Sun Woo ^a   Jung, Ju Young ^a   Kim, Wan Young ^a   Kim, Hyung Wook ^a   Choi, Bum Soon ^a   Li, Can ^a   Cha, Jung Ho ^a   Kim, Yong Soo ^a   Kim, Jin ^a   Bang, Byung Kee ^a  

^a The Catholic University of Korea   (South Korea)

Author keywords

Cyclosporine; Epidermal growth factor; FK506; Ischemia reperfusion injury

Indexed keywords

BROXURIDINE; CYCLOSPORIN A; EPIDERMAL GROWTH FACTOR; TACROLIMUS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY CLAMP; ARTICLE; BLOOD; CELL REGENERATION; CONTROLLED STUDY; DOSE RESPONSE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; KIDNEY CORTEX; KIDNEY FUNCTION; KIDNEY ISCHEMIA; KIDNEY MEDULLA; KIDNEY TUBULE CELL; KIDNEY TUBULE NECROSIS; MALE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RENAL ARTERY; REPERFUSION INJURY;

ANIMALS; ANTIMETABOLITES; BROMODEOXYURIDINE; CYCLOSPORINE; EPIDERMAL GROWTH FACTOR; IMMUNOSUPPRESSIVE AGENTS; KIDNEY TUBULES; MALE; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; TACROLIMUS;

EID: 0036969288     PISSN: 00282766     EISSN: None     Source Type: Journal    
DOI: 10.1159/000065435     Document Type: Article

References (35)

1. van Es A, Hermans J, van Bockel JH, Persijn GG, van Hooff JP, de Graeff J: Effect of warm ischemia time and HLA (A and B) matching on renal cadaveric graft survival and rejection episodes. Transplantation 1983;36:255-258.
2. Sanfillippo F, Vaughn WK, Spees EK, Lucas BA: The detrimental effects of delayed graft function in cadaver donor renal transplantation. Transplantation 1984;38:643-648.
3. Cole E, Naimark D, Aprile M, Wade J, Cattran D, Pei Y, Fenton S, Bobinette M, Zaltsman J, Bear R, et al: An analysis of predictors of long-term cadaveric renal allograft survival. Clin Transplant 1995;9:282-288.
4. Troppmann C, Gillingham KJ, Benedetti E, Almond PS, Gruessner RW, Najarian JS, Matas AJ: Delayed graft function, acute rejection, and outcome after cadaver renal transplantation: A multivariate analysis. Transplantation 1995;59:962-968.
5. Goes N, Urmson J, Ramassar V, Halloran PF: Ischemic acute tubular necrosis induces an extensive local cytokine response: Evidence for induction of interferon-r, transforming growth factor, interleukin-2, and interleukin-10, Transplantation 1995;59:565-572.
6. Barros EJ, Boim MA, Ajaen H, Ramos OL, Shor N: Glomerular hemodynamics and hormonal participation on cyclosporine nephrotoxicity. Kidney Int 1987;32:19-25.
7. Toback FG: Regeneration after acute tubular necrosis. Kidney Int 1992;41:226-246.
8. Bacallao R, Fine LG: Molecular events in the organization of renal tubularepithelium: From nephrogenesis to regeneration. Am J Physiol 1989;257:F913-F924.
9. Bonventre JV: Mechanisms of ischemic renal failure. Kidney Int 1993;43:1160-1178.
10. Humes HD, Lake EW, Liu S: Renal tubule cell repair following acute renal injury. Miner Electrolyte Metab 1995;21:353-365.
11. Burgess AW: Epidermal growth factor and transforming growth factor α. Br Med Bull 1989;45:401-424.
12. Das M, Rengaraju M, Samanta A: Epidermal growth factor; in Aggarwal BB, Gutterman JU (eds): Human Cytokines - Handbook for Basic and Clinical Research. Boston, Blackwell Scientific Publications, 1992, chap 21, pp 365-382.
13. Harris RC: Potential physiologic roles for epidermal growth factor in the kidney. Am J Kidney Dis 1991;17:627-630.
14. Taub M, Wang Y, Szczesny TM, Kleiman HK: Epidermal growth factor or transforming growth factor α is required for kidney tubulogenesis in matrigel cultures in serum-free medium. Proc Natl Acad Sci USA 1990;87:4002-4006.
15. Humes HD, Cieslinski DA, Coimbra TM, Messana JM, Galvao C: Epidermal growth factor enhances renal tubular cell regeneration and repair and accelerates the recovery of renal function in postischemic acute renal failure. J Clin Invest 1989;84:1757-1761.
16. Kanda S, Igawa T, Sakai H, Nomata K, Kanetake H, Saito Y: Anti-epidermal growth factor antibody inhibits compensatory renal hyperplasia but not hypertrophy after unilateral nephrectomy in mice. Biochem Biophys Res Commun 1992;187:1015-1021.
17. Myers BD: Cyclosporine nephrotoxicity. Kidney Int 1986:30:964-974.
18. Barros EJ, Boim MA, Ajzen H, Ramos OL, Schor N: Glomerular hemodynamics and hormonal participation on cyclosporine nephrotoxicity. Kidney Int 1987;32:19-25.
19. Ysebaert DK, De Greef KE, Nouwen EJ, Ver-pooten GA, Eyskens EJ, De Broe ME: Influence of cyclosporin A on the damage and regeneration of the kidney after severe ischemia/reperfusion injury. Transplant Proc 1997;29:2348-2351.
20. Nonclearcq D, Wrona S, Toubeau G, Zanen J, Heuson-Stiennon JA, Schaudies RP, Laurent G: Tubular injury and regeneration in the rat kidney following acute exposure to gentamicin: A time-course study. Renal Failure 1992;14: 507-521.
21. Schadies RP, Nonclearcq D, Nelson L, et al: Endogenous EGF as a potential renotrophic factor in ischemia-induced acute renal failure. Am J Physiol 1993;265:F425-F434.
22. Yang CW, Ahn HJ, Kim WY, Shin MJ, Kim SK, Park JH, Kim YO, Kim YS, Kim J, Bang BK: Influence of renin-angiotensin system on epidermal growth factor expression in normal and cyclosporine-treated rat kidney. Kidney Int 2001;60:847-857.
23. Norman J, Tsau YK, Bacay A, Fine LG: Epidermal growth factor accelerates functional recovery from ischemic acute tubular necrosis in the rat: Role of epidermal growth factor receptor. Clin Sci Lond 1990;78:445-450.
24. Coimbra TM, Cieslinski DA, Humes HD: Epidermal growth factor accelerates renal repair in mercuric chloride nephrotoxins. Am J Physiol 1990;259:F438-F443.
25. Alberti P, Bardella L, Comelli R: Ribosomal protein S6 kinase is activated after folic acid injury and epidermal growth factor administration but not after unilateral nephrectomy in the rat kidney. Nephron 1992;60:330-335.
26. Morin NJ, Laurent G, Nonclereq D, Toubeau G, Heuson-Stiennon JA, Bergeron MG, Beauchamp D: Epidermal growth factor (EGF) accelerates renal tissue repair in a rat model of gentamicin nephrotoxicity. Am J Physiol 1989; 51:123-140.
27. Verstrepen WA, Nouwen EJ, De Broe ME: Altered growth factor expression during toxic proximal tubular necrosis and regeneration. Kidney Int 1993;43:1267-1279.
28. Safirstein R, Zelent AZ, Price PM: Reduced renal prepro-epidermal growth factor mRNA and decreased EGF excretion in ARF. Kidney Int 1989;36:810-815.
29. Toubeau G, Nonclercq D, Zanen J, Laurent G, Schaudies PR, Heuson-Stiennon JA: Renal tissue expression of EGF and EGF receptor after ischaemic tubular injury: An immunohistochemical study. Exp Nephrol 1994;2:229-239.
30. Schadies RP, Johnson JP: Increased soluble EGF after ischemia is accompanied by a decrease in membrane-associated precursors. Am J Physiol 1993;264:F523-F531.
31. Safirstein R, Price PM, Saggi SJ, Harris RC: Changes in gene expression after temporary renal ischemia. Kidney Int 1990;37:1515-1521.
32. Yano T, Yazima S, Hagiwara K, Ozasa H, Ishizuka S, Horikawa S: Activation of epidermal growth factor receptor in the early phase after renal ischemia-reperfusion in rat. Nephron 1999;81:230-233.
33. Hammerman MR: Growth factors and apoptosis in acute renal injury. Curr Opin Nephrol Hypertens 1998;7:419-424.
34. Bia MJ, Tyler KA: Effect of cyclosporine on renal ischemic injury. Transplantation 1987; 43:800-804.
35. Yang CW, Kim BS, Kim J, Ahn HJ, Park JH, Jin DC, Kim YS, Bang BK: Preconditioning with sodium arsenite inhibits apoptotic cell death in rat kidney with ischemia/reperfusion or cyclosporine-induced injuries. Exp Nephrol 2001;9:284-294.