-
1
-
-
0030064088
-
Discovery of 1,5-benzodiazepines with peripheral cholecystokinin (CCK-A) receptor agonist activity 1. Optimization of the agonist "Trigger"
-
Aquino, C. J., D. R. Armour, J. M. Berman, L. S. Birkemo, R. A. E. Carr, D. K. Croom, M. Dezube, R. W. Dougherty, Jr., G. N. Ervin, M. K. Grizzle, J. E. Head, G. C. Hirst, M. K. James, M. F. Johnson, L. J. Miller, K. L. Queen, T. J. Rimele, D. N. Smith & E. E. Sugg: Discovery of 1,5-benzodiazepines with peripheral cholecystokinin (CCK-A) receptor agonist activity 1. Optimization of the agonist "Trigger". J. Med. Chem. 1996, 39, 562-569.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 562-569
-
-
Aquino, C.J.1
Armour, D.R.2
Berman, J.M.3
Birkemo, L.S.4
Carr, R.A.E.5
Croom, D.K.6
Dezube, M.7
Dougherty R.W., Jr.8
Ervin, G.N.9
Grizzle, M.K.10
Head, J.E.11
Hirst, G.C.12
James, M.K.13
Johnson, M.F.14
Miller, L.J.15
Queen, K.L.16
Rimele, T.J.17
Smith, D.N.18
Sugg, E.E.19
-
2
-
-
0024121476
-
Cyclic cholecystokinin analogues with high selectivity for central receptors
-
Charpentier, B., D. Pelaprat, C. Durieux, A. Dor, M. Reibaud, J. C. Blanchard & B. P. Roques: Cyclic cholecystokinin analogues with high selectivity for central receptors. Proc. Natl. Acad. Sci. USA 1988, 85, 1968-1972.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 1968-1972
-
-
Charpentier, B.1
Pelaprat, D.2
Durieux, C.3
Dor, A.4
Reibaud, M.5
Blanchard, J.C.6
Roques, B.P.7
-
3
-
-
0035930602
-
Agonist-dependent dissociation of oligomeric complexes of G protein-coupled cholecystokinin receptors demonstrated in living cells using bioluminescence resonance energy transfer
-
Cheng, Z. J. & L. J. Miller: Agonist-dependent dissociation of oligomeric complexes of G protein-coupled cholecystokinin receptors demonstrated in living cells using bioluminescence resonance energy transfer. J. Biol. Chem. 2001, 276, 48040-28047.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 48040-28047
-
-
Cheng, Z.J.1
Miller, L.J.2
-
4
-
-
0032542043
-
Structurally similar small molecule photoaffinity CCK-A agonists and antagonists as novel tools for directly probing 7TM receptor-ligand interactions
-
Darrow, J. W., E. M. Hadac, L. J. Miller & E. E. Sugg: Structurally similar small molecule photoaffinity CCK-A agonists and antagonists as novel tools for directly probing 7TM receptor-ligand interactions. Bioorg. Med. Chem. Lett. 1998, 8, 3127-3132.
-
(1998)
Bioorg. Med. Chem. Lett.
, vol.8
, pp. 3127-3132
-
-
Darrow, J.W.1
Hadac, E.M.2
Miller, L.J.3
Sugg, E.E.4
-
5
-
-
0035830920
-
Refinement of the structure of the ligand-occupied cholecystokinin receptor using a photolabile amino-terminal probe
-
Ding, X. Q., V. Dolu, E. M. Hadac, E. L. Holicky, D. I. Pinon, T. P. Lybrand & L. J. Miller: Refinement of the structure of the ligand-occupied cholecystokinin receptor using a photolabile amino-terminal probe. J. Biol. Chem. 2001, 276, 4236-4244.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 4236-4244
-
-
Ding, X.Q.1
Dolu, V.2
Hadac, E.M.3
Holicky, E.L.4
Pinon, D.I.5
Lybrand, T.P.6
Miller, L.J.7
-
6
-
-
0036233457
-
Refinement of the conformation of a critical region of charge-charge interaction between cholecystokinin and its receptor
-
Ding, X. Q., D. I. Pinon, K. E. Furse, T. P. Lybrand & L. J. Miller: Refinement of the conformation of a critical region of charge-charge interaction between cholecystokinin and its receptor. Mol. Pharmacol. 2002, 61, 1041-1052.
-
(2002)
Mol. Pharmacol.
, vol.61
, pp. 1041-1052
-
-
Ding, X.Q.1
Pinon, D.I.2
Furse, K.E.3
Lybrand, T.P.4
Miller, L.J.5
-
7
-
-
0016240087
-
Photoaffinity labeling of peptide hormone binding sites
-
Galardy, R. E., L. C. Craig, J. D. Jamieson & M. P. Printz: Photoaffinity labeling of peptide hormone binding sites. J. Biol. Chem. 1974, 249, 3510-3518.
-
(1974)
J. Biol. Chem.
, vol.249
, pp. 3510-3518
-
-
Galardy, R.E.1
Craig, L.C.2
Jamieson, J.D.3
Printz, M.P.4
-
8
-
-
0033575274
-
Arginine 336 and asparagine 333 of the human cholecystokinin-A receptor binding site interact with the penultimate aspartic acid and the C-terminal amide of cholecystokinin
-
Gigoux, V., C. Escrieut, J. A. Fehrentz, S. Poirot, B. Maigret, L. Moroder, D. Gully, J. Martinez, N. Vaysse & D. Fourmy: Arginine 336 and asparagine 333 of the human cholecystokinin-A receptor binding site interact with the penultimate aspartic acid and the C-terminal amide of cholecystokinin. J. Biol. Chem. 1999, 274, 20457-20464.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 20457-20464
-
-
Gigoux, V.1
Escrieut, C.2
Fehrentz, J.A.3
Poirot, S.4
Maigret, B.5
Moroder, L.6
Gully, D.7
Martinez, J.8
Vaysse, N.9
Fourmy, D.10
-
9
-
-
0031859218
-
Identification of a domain in the carboxy terminus of CCK receptor that affects its intracellular trafficking
-
Go, W. Y., E. L. Holicky, E. M. Hadac, R. V. Rao & L. J. Miller: Identification of a domain in the carboxy terminus of CCK receptor that affects its intracellular trafficking. Amer. J. Physiol. 1998, 275, G56-G62.
-
(1998)
Amer. J. Physiol.
, vol.275
-
-
Go, W.Y.1
Holicky, E.L.2
Hadac, E.M.3
Rao, R.V.4
Miller, L.J.5
-
10
-
-
0034681373
-
1 receptor for interactions with SR 146131, SR 27897 and CCK-8S
-
1 receptor for interactions with SR 146131, SR 27897 and CCK-8S. Eur. J. Pharmacol. 2000, 389, 115-124.
-
(2000)
Eur. J. Pharmacol.
, vol.389
, pp. 115-124
-
-
Gouldson, P.1
Legoux, P.2
Carillon, C.3
Dumont, X.4
Le Fur, G.5
Ferrara, P.6
Shire, D.7
-
11
-
-
0033578084
-
A peptide agonist acts by occupation of a monomeric G protein-coupled receptor: Dual sites of covalent attachment to domains near TM1 and TM7 of the same molecule make biologically significant domain-swapped dimerization unlikely
-
Hadac, E. M., Z. S. Ji, D. I. Pinon, R. M. Henne, T. P. Lybrand & L. J. Miller: A peptide agonist acts by occupation of a monomeric G protein-coupled receptor: Dual sites of covalent attachment to domains near TM1 and TM7 of the same molecule make biologically significant domain-swapped dimerization unlikely. J. Med. Chem. 1999, 42, 2105-2111.
-
(1999)
J. Med. Chem.
, vol.42
, pp. 2105-2111
-
-
Hadac, E.M.1
Ji, Z.S.2
Pinon, D.I.3
Henne, R.M.4
Lybrand, T.P.5
Miller, L.J.6
-
12
-
-
0032557448
-
Direct identification of a second distinct site of contact between cholecystokinin and its receptor
-
Hadac, E. M., D. I. Pinon, Z. Ji, E. L. Holicky, R. Henne, T. Lybrand & L. J. Miller: Direct identification of a second distinct site of contact between cholecystokinin and its receptor. J. Biol. Chem. 1998, 273, 12988-12993.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 12988-12993
-
-
Hadac, E.M.1
Pinon, D.I.2
Ji, Z.3
Holicky, E.L.4
Henne, R.5
Lybrand, T.6
Miller, L.J.7
-
13
-
-
0025036194
-
Cholecystokinin analogues with high affinity and selectivity for brain membrane receptors
-
Hruby, V. J., S. A. Fang, R. Knapp, W. Kazmierski, G. K. Lui & H. I. Yamamura: Cholecystokinin analogues with high affinity and selectivity for brain membrane receptors. Int. J. Pept. Protein Res. 1990, 35, 566-573.
-
(1990)
Int. J. Pept. Protein Res.
, vol.35
, pp. 566-573
-
-
Hruby, V.J.1
Fang, S.A.2
Knapp, R.3
Kazmierski, W.4
Lui, G.K.5
Yamamura, H.I.6
-
14
-
-
0030846864
-
Direct identification of a distinct site of interaction between the carboxyl-terminal residue of cholecystokinin and the type A cholecystokinin receptor using photoaffinity labeling
-
Ji, Z. S., E. M. Hadac, R. M. Henne, S. A. Patel, T. P. Lybrand & L. J. Miller: Direct identification of a distinct site of interaction between the carboxyl-terminal residue of cholecystokinin and the type A cholecystokinin receptor using photoaffinity labeling. J. Biol. Chem. 1997, 272, 24393-24401.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 24393-24401
-
-
Ji, Z.S.1
Hadac, E.M.2
Henne, R.M.3
Patel, S.A.4
Lybrand, T.P.5
Miller, L.J.6
-
15
-
-
15644364730
-
Identification of two amino acids of the human cholecystokinin-A receptor that interact with the N-terminal moiety of cholecystokinin
-
Kennedy, K., V. Gigoux, C. Escrieut, J. Martinez, L. Moroder, D. Frehel, D. Gully, N. Vayse & D. Fourmy: Identification of two amino acids of the human cholecystokinin-A receptor that interact with the N-terminal moiety of cholecystokinin. J. Biol. Chem. 1997, 272, 2920-2926.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 2920-2926
-
-
Kennedy, K.1
Gigoux, V.2
Escrieut, C.3
Martinez, J.4
Moroder, L.5
Frehel, D.6
Gully, D.7
Vayse, N.8
Fourmy, D.9
-
16
-
-
0025574397
-
The efficiency of covalent labeling of the pancreatic cholecystokinin receptor using a battery of cross-linkable and photolabile probes
-
Klueppelberg, U. G., S. P. Powers & L. J. Miller: The efficiency of covalent labeling of the pancreatic cholecystokinin receptor using a battery of cross-linkable and photolabile probes. Receptor 1990, 1, 1-11.
-
(1990)
Receptor
, vol.1
, pp. 1-11
-
-
Klueppelberg, U.G.1
Powers, S.P.2
Miller, L.J.3
-
17
-
-
0023667814
-
Conformational analysis of the cholecystokinin C-terminal octapeptide: A nuclear magnetic resonance and computer- simulation approach
-
Loomis, R. E., P. C. Lee & C. C. Tseng: Conformational analysis of the cholecystokinin C-terminal octapeptide: a nuclear magnetic resonance and computer- simulation approach. Biochim. Biophys. Acta 1987, 911, 168-179.
-
(1987)
Biochim. Biophys. Acta
, vol.911
, pp. 168-179
-
-
Loomis, R.E.1
Lee, P.C.2
Tseng, C.C.3
-
18
-
-
0027323245
-
Solution conformation of CCK9, a cholecystokinin analog
-
Moroder, L., A. D'Ursi, D. Picone, P. Amodeo & P. A. Temussi: Solution conformation of CCK9, a cholecystokinin analog. Biochem. Biophys. Res. Commun. 1993, 190, 741-746.
-
(1993)
Biochem. Biophys. Res. Commun.
, vol.190
, pp. 741-746
-
-
Moroder, L.1
D'Ursi, A.2
Picone, D.3
Amodeo, P.4
Temussi, P.A.5
-
19
-
-
0014739644
-
Cholecystokinin-pancreozymin. Recent developments
-
Ondetti, M. A., B. Rubin, S. L. Engel, J. Pluscec & J. T. Sheehan: Cholecystokinin-pancreozymin. Recent developments. Amer. J. Dig. Dis. 1970, 15, 149-156.
-
(1970)
Amer. J. Dig. Dis.
, vol.15
, pp. 149-156
-
-
Ondetti, M.A.1
Rubin, B.2
Engel, S.L.3
Pluscec, J.4
Sheehan, J.T.5
-
20
-
-
0034604451
-
Crystal structure of rhodopsin: A G protein-coupled receptor
-
Palczewski, K., T. Kumasaka, T. Hori, C. A. Behnke, H. Motoshima, B. A. Fox, I. Le. Trong, D. C. Teller, T. Okada, R. E. Stenkamp, M. Yamamoto & M. Miyano: Crystal structure of rhodopsin: A G protein-coupled receptor. Science 2000, 289, 739-745.
-
(2000)
Science
, vol.289
, pp. 739-745
-
-
Palczewski, K.1
Kumasaka, T.2
Hori, T.3
Behnke, C.A.4
Motoshima, H.5
Fox, B.A.6
Trong, I.Le.7
Teller, D.C.8
Okada, T.9
Stenkamp, R.E.10
Yamamoto, M.11
Miyano, M.12
-
21
-
-
0023125680
-
Affinity labeling of a novel cholecystokinin-binding protein in rat pancreatic plasmalemma using new short probes for the receptor
-
Pearson, R. K. & L. J. Miller: Affinity labeling of a novel cholecystokinin-binding protein in rat pancreatic plasmalemma using new short probes for the receptor. J. Biol. Chem. 1987, 262, 869-876.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 869-876
-
-
Pearson, R.K.1
Miller, L.J.2
-
22
-
-
0031818991
-
Role of the extracellular domains of the cholecystokinin receptor in agonist binding
-
Silvente-Poirot, S., C. Escrieut & S. A. Wank: Role of the extracellular domains of the cholecystokinin receptor in agonist binding. Mol. Pharmacol. 1998, 54, 364-371.
-
(1998)
Mol. Pharmacol.
, vol.54
, pp. 364-371
-
-
Silvente-Poirot, S.1
Escrieut, C.2
Wank, S.A.3
-
23
-
-
0026057332
-
Allele-specific activation of genetically engineered receptors
-
Strader, C. D., T. Gaffney, E. E. Sugg, M. R. Candelore, R. Keys, A. A. Patchett & R. A. F. Dixon: Allele-specific activation of genetically engineered receptors. J. Biol. Chem. 1991, 266, 5-8.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 5-8
-
-
Strader, C.D.1
Gaffney, T.2
Sugg, E.E.3
Candelore, M.R.4
Keys, R.5
Patchett, A.A.6
Dixon, R.A.F.7
-
24
-
-
0026559686
-
Purification, molecular cloning, and functional expression of the cholecystokinin receptor from rat pancreas
-
Wank, S. A., R. Harkins, R. T. Jensen, H. Shapira, A. De Weerth & T. Slattery: Purification, molecular cloning, and functional expression of the cholecystokinin receptor from rat pancreas. Proc. Natl. Acad. Sci. U. S. A. 1992, 89, 3125-3129.
-
(1992)
Proc. Natl. Acad. Sci. U. S. A.
, vol.89
, pp. 3125-3129
-
-
Wank, S.A.1
Harkins, R.2
Jensen, R.T.3
Shapira, H.4
De Weerth, A.5
Slattery, T.6
-
25
-
-
0022481476
-
Conformational analysis of cholecystokinin CCK26-33 and related fragments by 1H NMR spectroscopy, fluorescence-transfer measurements, and calculations
-
Zaluski, M. C. Fournie, J. Belleney, B. Lux, C. Durieux, D. Gerard, G. Gacel, B. Maigret & B. P. Roques: Conformational analysis of cholecystokinin CCK26-33 and related fragments by 1H NMR spectroscopy, fluorescence-transfer measurements, and calculations. Biochemistry 1986, 25, 3778-3787.
-
(1986)
Biochemistry
, vol.25
, pp. 3778-3787
-
-
Zaluski1
Fournie, M.C.2
Belleney, J.3
Lux, B.4
Durieux, D.5
Gerard, D.6
Gacel, B.7
Maigret, B.8
Roques, B.P.9
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