Effectiveness of willow bark extract in painful conditions;Wirksamkeit von weidenrindenextrakt bei schmerzen

Zeitschrift fur Phytotherapie

Volumn 23, Issue 6, 2002, Pages 263-266

  Chrubasik, Sigrun ^a   Pollak, Stefan ^a  

^a NONE

Author keywords

Assalix ; Inflammation; Joint pain; Low back pain; Salix; Willow bark

Indexed keywords

ACETYLSALICYLIC ACID; ANTIRHEUMATIC AGENT; ASSALIX; PLACEBO; PLANT EXTRACT; ROFECOXIB; SALICIN; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ARTHRALGIA; ARTICLE; BARK; CARTILAGE; CLINICAL TRIAL; HOT PLATE TEST; HUMAN; LOW BACK PAIN; NONHUMAN; OSTEOARTHRITIS; PHYTOTHERAPY; THROMBOCYTE AGGREGATION; WILLOW;

EID: 0036968448     PISSN: 0722348X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Bjorkman D: Nonsteroidal anti-inflammatory drug-related toxicity of the liver, lower gastrointestinal tract, and esophagus. Am J Med 1998; 105: 17S-21S.
2. Chrubasik S, Eisenberg E, Balan E, et al.: Treatment of low back pain exacerbations with willow bark extrakt: a randomised double-blind study. Am J Med 2000; 109: 9-14.
3. Chrubasik S, Künzel O, Acker A, et al.: Preliminary data on the effectiveness, safety and treatment cost of a willow bark special extract in outpatient treatment of low back pain: an open controlled study. Phytomedicine 2001; 8: 241-251.
4. Chrubasik S, Fiebich B, Black A, Pollak S: Treating low back pain with a Salix extract that inhibits COX-2 release and the release of cytokines. Eur J Anaesthesiol 2002; 19: 209-210.
5. Chrubasik S, Künzel O, Model A, Conradt C, Black A: Treatment of low back pain with a herbal or synthetic antirheumatic: a randomized controlled study. Rheumatology 2001; 40: 1388-1393.
6. ESCOP Monograph: Salicis Cortex (Willow Bark). Fascicule 4; 1997.
7. Krivoy N, Pavlotzky E, Chrubasik S, Eisenberg E, Brooks G: Effect of Salicis Cortex extract on human platelet aggregation. Planta medica 2001; 67: 209-213.
8. Kuppusamy UR, Khoo HE, Das NP: Structure-activity studies of flavonoids as inhibitors of hyaluronidase. Biochem Pharmacol 1990; 40: 397-401.
9. Leslie GB: A pharmacometric evaluation of nine Bio-Strath herbal remedies. Medica 1978; 10: 31-47.
10. Leslie GB, Salmon G: Untersuchungen über Toxizität und Reproduktion mit wiederholten Dosen von neun Bio-Strath Heilpflanzen-Präparaten. Swiss Medicale 1979; 1: 43-45.
11. Loniewski I, Glinko A, Samochowiec L: Standardised willow bark extract: a potent anti-inflammatory drug. FACT (Focus in Alternative and Complementary Therapy) Suppl 2002; 7: 100.
12. Maier B: Analytik, chromatographisches Verhalten und potentielle Wirksamkeit der Inhaltsstoffe salizylathaltiger Arzneipflanzen Mitteleuropas [Habilitationsschrift]. Zürich: Eidgenössische Technische Hochschule; 1988.
13. McCarthy D: Nonsteroidal anti-inflammatory drug-related gastrointestinal toxicity: definitions and epidemiology. Am J Med 1998; 105: 3S-9S.
14. Rohnert U, Schneider W, Elstner EF: Superoxide-dependent and -independent nitrite formation from hydroxylamine: inhibition by plant extracts. J Biosci 1998; 53: 241-249.
15. Schmid B, Kötter I, Heide L: Pharmacokinetics of salicin after oral administration of a standardised willow bark extract. Eur J Clin Pharmacol 2001; 57: 387-391.
16. Schmid B, Lüdtke R, Selbmann HK, et al.: Wirksamkeit und Verträglichkeit eines standardisierten Weidenrindenextrakts bei Arthrose-Patienten: Randomisierte, plazebo-kontrollierte Doppelblindstudie. Z Rheumatologie 2000; 59: 1-7.
17. Steinegger E, Hövel H: Analytische und biologische Untersuchungen an Salicaceen-Wirkstoffen, insbesondere Salicin. II. Biologische Untersuchungen. Pharm Acta Helv 1972; 47: 222-234.
18. Wurm G, Baumann J, Geres U: Beeinflussung des Arachidonsäurestoffwechsels durch Flavonoide. Dtsch Apotheker Ztg 1982; 122: 2062-2068.