Longitudinal follow-up of TTS-fentanyl use in patients with cancer-related pain: Results of a compassionate-use study with special focus on elderly patients

Current Medical Research and Opinion

Volumn 18, Issue 8, 2002, Pages 488-498

  Menten, J ^a   Desmedt, M ^b   Lossignol, D ^c   Mullie, A ^d  

^a UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^b CLINIQUES UNIVERSITAIRES SAINT LUC   (Belgium)

^c JULES BORDET INSTITUTE   (Belgium)

^d General Hospital St Jan   (Belgium)

Author keywords

Cancer pain; Constipation; Elderly patient; Tolerability; Transdermal fentanyl

Indexed keywords

ACETYLSALICYLIC ACID; CODEINE; FENTANYL; LAXATIVE; MORPHINE; OPIATE; PARACETAMOL;

ADULT; AGED; ANALGESIA; ARTICLE; CANCER PAIN; CLINICAL TRIAL; CONFUSION; CONSTIPATION; COUGHING; DISEASE SEVERITY; DOSE RESPONSE; DOSE TIME EFFECT RELATION; DRUG DELIVERY SYSTEM; DRUG OVERDOSE; DRUG SCREENING; DRUG TOLERABILITY; DRUG USE; DYSPNEA; ELDERLY CARE; FATALITY; FEMALE; FOLLOW UP; GASTROINTESTINAL SYMPTOM; HEADACHE; HEMATURIA; HUMAN; LONG TERM CARE; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MENTAL DISEASE; MULTICENTER STUDY; NAUSEA; NEUROLOGIC DISEASE; PATIENT ATTITUDE; PATIENT CARE; PRURITUS; REGISTER; RESPIRATION DEPRESSION; SKIN DISEASE; SOMNOLENCE; SWEATING; TIMED DRUG RELEASE; URINE RETENTION; VERTIGO; VOMITING;

ADMINISTRATION, CUTANEOUS; AGED; ANALGESICS, OPIOID; CONSTIPATION; FEMALE; FENTANYL; FOLLOW-UP STUDIES; HUMANS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; NEOPLASMS; PAIN; PALLIATIVE CARE;

EID: 0036966165     PISSN: 03007995     EISSN: None     Source Type: Journal    
DOI: 10.1185/030079902125001272     Document Type: Article

References (18)

1. Cleary JF. Cancer pain management. Cancer Control 2000;7:120-31
2. Jacox A, Carr DB, Payne R. Management of cancer pain. Clinical Practice Guideline Number 9. Rockville: AHCPR, 1994
3. Portenoy RK, Lesage P. Management of cancer pain. Lancet 1999;353:1695-700
4. Ahmedzai S, Brooks D. Transdermal fentanyl versus sustained-release oral morphine in cancer pain: preference, efficacy, and quality of life. The TTS-Fentanyl Comparative Trial Group. J Pain Symptom Manage 1997;13:254-61
5. Hunt R, Fazekas B, Thorne D, Brooksbank M. A comparison of subcutaneous morphine and fentanyl in hospice cancer patients. J Pain Symptom Manage 1999;18:111-19
6. Payne R. Factors influencing quality of life in cancer patients: the role of transdermal fentanyl in the management of pain. Semin Oncol 1998;25:47-53
7. Southam MA. Transdermal fentanyl therapy: system design, pharmacokinetics and efficacy. Anticancer Drugs 1995;6 Suppl 3:29-34
8. Donner B, Zenz M, Strumpf M, Raber M. Long-term treatment of cancer pain with transdermal fentanyl. J Pain Symptom Manage 1998;15:168-75
9. Simmonds MA, Richenbacher J. Transdermal fentanyl: long-term analgesic studies. J Pain Symptom Manage 1992;7:S36-9
10. Sloan PA, Moulin DE, Hays H. A clinical evaluation of transdermal therapeutic system fentanyl for the treatment of cancer pain. J Pain Symptom Manage 1998;16:102-11
11. Zech DF, Grond SU, Lynch J, Dauer HG, Stollenwerk B, Lehmann KA. Transdermal fentanyl and initial dose-finding with patient-controlled analgesia in cancer pain. A pilot study with 20 terminally ill cancer patients. Pain 1992;50:293-301
12. Payne R, Mathias SD, Pasta DJ, Wanke LA, Williams R, Mahmoud R. Quality of life and cancer pain: satisfaction and side-effects with transdermal fentanyl versus oral morphine. J Clin Oncol 1998;16:1588-93
13. Jeal W, Benfield P. Transdermal fentanyl. A review of its pharmacological properties and therapeutic efficacy in pain control. Drugs 1997;53:109-38
14. Iconomou G, Viha A, Vagenakis AG, Kalofonos HP. Transdermal fentanyl in cancer patients with moderate-to-severe pain: a prospective examination. Anticancer Res 2000;20:4821-4
15. Radbruch L, Sabatowski R, Loick G, Kulbe C, Kasper M, Grond S et al. Constipation and the use of laxatives: a comparison between transdermal fentanyl and oral morphine. Palliat Med 2000;14:111-9
16. Breitbart W, Chandler S, Eagel B, Ellison N, Erick RE, Lefkowitz M, Payne R. An alternative algorithm for dosing transdermal fentanyl for cancer-related pain. Oncology (Huntingt) 2000;14:695-705
17. Jakobsson M, Strang P. Fentanyl patches for the treatment of pain in dying cancer patients. Anticancer Res 1999;19:4441-2
18. Vielvoye-Kerkmeer AP, Mattern C, Uitendaal MP. Transdermal fentanyl in opioid-naive cancer pain patients: an open trial using transdermal fentanyl for the treatment of chronic cancer pain in opioid-naive patients and a group using codeine. J Pain Symptom Manage 2000;19:185-92