Curcumin induces caspase-3-independent apoptosis in human multidrug-resistant cells

Annals of the New York Academy of Sciences

Volumn 973, Issue , 2002, Pages 250-254

  Piwocka, Katarzyna ^a   Bielak Zmijewska, Anna ^a   Sikora, Ewa ^a  

^a NENCKI INSTITUTE OF EXPERIMENTAL BIOLOGY   (Poland)

Author keywords

Cell death; Curcumin; MDR cells

Indexed keywords

CASPASE 3; CURCUMIN;

APOPTOSIS; CELL DEATH; CELL STRUCTURE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MULTIDRUG RESISTANCE; NICK END LABELING;

CURCUMA LONGA;

EID: 0036962084     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2002.tb04643.x     Document Type: Conference Paper

References (5)

1. PIWOCKA, K., K. ZABLOCKI, M. WIECKOWSKI, et al. 1999. A novel apoptosis-like pathway, independent of mitochondria and caspases, induced by curcumin in human lymphoblastoid T (Jurkat) cells. Exp. Cell Res. 249: 299-307.
2. PIWOCKA, K., E. JARUGA, J. SKIERSKI, et al. 2001. Effect of glutathione depletion on caspase-3 independent apoptosis pathway induced by curcumin in Jurkat cells. Free Radical Biol. Med. 31: 670-678.
3. BIELAK-ZMIJEWSKA, A., M. KORONKIEWICZ, J. SKIERSKI, et al. 2000. Effect of curcumin on the apoptosis of rodent and human nonproliferating and proliferating lymphoid cells. Nutr. Cancer 38: 131-138.
4. JOHNSTONE, R.W., E. CRETNEY & M.J. SMYTH. 1999. P-glycoprotein protects leukemia cells against caspase-dependent, but not caspase-independent, cell death. Blood 93: 1075-1085.
5. JOHNSTONE, R.W., A.A. RUEFLI, K.M. TAINTON & M.J. SMYTH. 2000. A role for P-glycoprotein in regulating cell death. Leuk. Lymphoma 38: 1-11.