Metamorphosis of the selenoprotein PHGPx during spermatogenesis

Annals of the New York Academy of Sciences

Volumn 973, Issue , 2002, Pages 287-288

  Flohé, Leopold ^a   Foresta, Carlo ^b   Garolla, Andrea ^b   Maiorino, Matilde ^b   Roveri, Antonella ^b   Ursini, Fulvio ^b  

^a TECHNICAL UNIVERSITY OF BRAUNSCHWEIG   (Germany)

^b UNIVERSITY OF PADOVA   (Italy)

Author keywords

Fertility; PHGPx; Selenoprotein; Spermatogenesis

Indexed keywords

PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE PEROXIDASE; SELENOPROTEIN;

ALTERNATIVE RNA SPLICING; CONFERENCE PAPER; CROSS LINKING; ENZYME ACTIVITY; HUMAN; MALE FERTILITY; METAMORPHOSIS; NONHUMAN; OXIDATIVE STRESS; PROTEIN ANALYSIS; PROTEIN FUNCTION; SELENIUM DEFICIENCY; SPERMATOGENESIS; SPERMATOZOON COUNT;

EID: 0036961802     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2002.tb04651.x     Document Type: Conference Paper

References (7)

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2. ROVERI, A., A. CASASCO, M. MAIORINO, et al. 1992. Phospholipid hydroperoxide glutathione peroxidase of rat testis: gonadotropin dependency and immunocytochemical identification. J. Biol. Chem. 267: 6142-6146.
3. MAIORINO, M., J.B. WISSING, R. BRIGELIUS-FLOHÉ, et al. 1998. Testosterone mediates expression of the selenoprotein PHGPx by induction of spermatogenesis and not by direct transcriptional gene activation. FASEB J. 12: 1359-1370.
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6. URSINI, F., S. HEIM, M. KIESS, et al. 1999. Dual function of the selenoprotein PHGPx during sperm maturation. Science 285: 1393-1396.
7. IMAI, H., K. SUZUKI, K. ISHIZAKA, et al. 2001. Failure of expression of phospholipid hydroperoxide glutathione peroxidase in the spermatozoa of human infertile males. Biol. Reprod. 64: 674-683.