LDL apheresis: An effective and safe treatment for refractory hypercholesterolemia

Cardiovascular Drug Reviews

Volumn 20, Issue 4, 2002, Pages 271-280

  Hudgins, Lisa Cooper ^a   Gordon, Bruce R ^a   Parker, Thomas S ^a   Saal, Stuart D ^a   Levine, Daniel M ^a   Rubin, Albert L ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Cholesterol; DALI; Familial hypercholesterolemia; HELP; LDL apheresis; Lipids; Liposorber

Indexed keywords

ANTIBODY; APOLIPOPROTEIN B; CELLULOSE; DEXTRAN SULFATE; HEPARIN; LIPID; LIPOPROTEIN A; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; VERY LOW DENSITY LIPOPROTEIN;

APHERESIS; CHOLESTEROL BLOOD LEVEL; COMPARATIVE STUDY; CORONARY ARTERY DISEASE; COST BENEFIT ANALYSIS; DIET; DISABILITY; FAMILIAL HYPERCHOLESTEROLEMIA; FOOD AND DRUG ADMINISTRATION; HEART PROTECTION; HUMAN; HYPERCHOLESTEROLEMIA; IMMUNOADSORPTION; LONGEVITY; PLASMAPHERESIS; PRECIPITATION; PRIORITY JOURNAL; REVIEW; THORAX PAIN; UNITED STATES;

EID: 0036961489     PISSN: 08975957     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1527-3466.2002.tb00097.x     Document Type: Review

References (27)

1. Aengevaeren WRM, Kroon AA, Stalenhoef AFH, et al. Low density lipoprotein apheresis improves regional myocardial perfusion in patients with hypercholesterolemia and extensive coronary artery disease. J Am Coll Cardiol 1996;28:1696-1704.
2. Borberg H, Oette K: Experience with and conclusions from three different trials on low density lipoprotein apheresis. In: Therapeutic Plasmapheresis. Vol. XII, Agishi T, Kawamura A, and Mineshima M., Eds. VSP, 1993;13-20.
3. Bosch T, Schmidt B, Kleophas W, et al. LDL-hemoperfusion - A new procedure for LDL-apheresis: First clinical application of an LDL-adsorber compatible with human whole blood. Artif Organs 1997;21:977-982.
4. Bosch T. Direct adsortpion of lipoproteins from whole blood by DALI apheresis: technique and effects. Therapeutic Apheresis 2001;5:239-243.
5. Brunner R, Widder RA, Walter P, et al. Change in hemorrheological and biochemical parameters following membrane differential filtration. Int J Artif Organs 1995;18:794-798.
6. de Gennes JL, Touraine R, Maunand B, et al. Homozygous cutaneotendinous forms of hypercholesterolemic xanthomatosis in an exemplary familial case. Trial of plasmapheresis as an heroic treatment. Bull Mem Soc Hosp (Paris) 1967;118:1377-1402.
7. Goldstein JL, Brown MS. The LDL receptor defect in familial hypercholesterolemia. Implications for pathogenesis and therapy. Med Clin North Am 1982;66:335-362.
8. Goldstein JL, Hobbs HH, Brown MS. Familial hypercholesterolemia. In: Scriver CR, et al., Eds. The metabolic and molecular basis of inherited disease. New York: McGraw-Hill, 2001;2863-2913.
9. Gordon BR, Kelsey SF, Bilheimer DW, et al. Long-term effects of LDL apheresis using an automated dextran sulfate cellulose adsorption system. Am J Cardiol 1998;81:407-411.
10. Gordon BR, Kelsey SF, Bilheimer DW, et al. Treatment of refractory familial hypercholesterolemia by low-density lipoprotein apheresis using an automated dextran sulfate cellulose adsorption system. Am J Cardiol 1992;70:1010-1016.
11. Gordon BR, Sloan BJ, Parker TS, et al. Humoral immune response following extracorporeal immunoadsorption therapy of patients with hypercholesterolemia. Transfusion 1990;30:318-321.
12. Gordon BR and Hudgins LC. The steps beyond diet and drug therapy for severe hypercholesterolemia. In: Antman AM, Ed. Cardiovascular therapeutics. New York: W. B. Saunders Co., 2002;589-600.
13. Kroon AA, Aengevaeren WRM, van der Werf T, et al. LDL-apheresis atherosclerosis regression study (LAARS). Effect of aggressive versus conventional lipid lowering treatment on coronary atherosclerosis. Circulation 1996;93:1826-1835.
14. Lupien PJ, Moorjani S, Awad J. A new approach to the management of familial hypercholesterolemia: Removal of plasma cholesterol based on the principle of affinity chromatography. Lancet 1976;1:1261-1264.
15. Mabuchi H, Koizumi J, Shimizu M, et al. Long-term efficacy of low density lipoprotein apheresis on coronary heart disease in familial hypercholesterolemia. Am J Cardiol 1998;82:1489-1495.
16. Olbricht CJ, Schaumann D, Fischer D. Anaphylactoid reactions, LDL apheresis with dextran sulphate, and ACE inhibitors. Lancet 1992;340:908-909.
17. Parker TS, Gordon BR, Saal SD, et al. Plasma high density lipoprotein is increased in man when low density lipoprotein (LDL) is lowered by LDL-pheresis. Proc Natl Acad Sci USA 1986;83:777-781.
18. Saal, SD, Parker, TS, Gordon, BR, et al. Removal of low-density lipoproteins in patients by extracorporeal immunoadsorption. Am J Med 1986;80:583-589.
19. Schuff-Werner P, Armstrong VW, Eisenhauer TH, et al. Treatment of severe hypercholesterolemia by heparin-induced extracorporeal LDL precipitation (HELP). Contrib Infus Ther 1988;23:118-126.
20. Schuff-Werner P, Gohlke H, Bartmann U, et al. The HELP-LDL Apheresis Multicenter Study, an angiographically assessed trial on the role of LDL apheresis in the secondary prevention of coronary heart disease. II. Final evaluation of the effect of regular treatment on LDL-cholesterol plasma concentrations and the course of coronary heart disease. Eur J Clin Invest 1994;24:724-732.
21. Stoffel W, Borberg H, Greve V. Application of specific extracorporeal removal of low density lipoprotein in familial hypercholesterolaemia. Lancet 1981;11:1005-1007.
22. Tamai O, Matsuoka H, Itabe H, et al. Single LDL apheresis improves endothelium-dependent vasodilation in hypercholesterolemic humans. Circulation 1997;95:76-82.
23. Tatami R, Inoue N, Itoh H, et al. Regression of coronary atherosclerosis by combined LDL apheresis and lipid-lowering drug therapy in patients with familial hypercholesterolemia: A multicenter study. Atherosclerosis 1992;95:1-13.
24. Thompson GR, Lowenthal R, Myant NB. Plasma exchange in the management of homozygous familial hypercholesterolaemia. Lancet 1975;1:1208-1211.
25. Thompson GR, Miller JP, Breslow JL. Improved survival of patients with homozygous familial hypercholesterolaemia treated with plasma exchange. Br Med J 1985;291:1671-1673.
26. Uno H, Ueki Y, Murashima J, et al. Removal of LDL from plasma by adsorption reduces adhesion molecules on mononuclear cells in patients with arteriosclerotic obliterance. Atherosclerosis 1995;116:93-102.
27. Yokoyama S, Hayashi R, Satani M, Yamamoto A. Selective removal of low density lipoprotein by plasmapheresis in familial hypercholesterolemia. Arteriosclerosis 1985;5:613-622.