Comprehensive phenotyping of sensory neurons using an ex vivo somatosensory system

Physiology and Behavior

Volumn 77, Issue 4-5, 2002, Pages 589-594

  Koerber, H Richard ^a   Woodbury, C Jeffery ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Dorsal root ganglia; Intracellular recording; Pain; Primary afferent fibers; Skin; Spinal cord

Indexed keywords

AVIDIN; BIOTIN; CALCITONIN GENE RELATED PEPTIDE; DIAMINOBENZIDINE; OXYGEN;

ADOLESCENT; ANIMAL TISSUE; ARTICLE; ARTIFICIAL VENTILATION; CEREBROSPINAL FLUID EXAMINATION; GANGLION; HORSERADISH; IN VIVO STUDY; LAMINAR AIRFLOW; MECHANORECEPTOR; MOUSE; NEWBORN; NONHUMAN; PERCEPTIVE THRESHOLD; PERFUSION; PHENOTYPE; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; RAT; SENSORY NERVE CELL; SKIN NERVE; SKIN SENSATION; SOMATOSENSORY SYSTEM; SPINAL CORD; SPINAL CORD TRANSSECTION; SPINAL GANGLION; STIMULUS RESPONSE;

EID: 0036954984     PISSN: 00319384     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-9384(02)00904-6     Document Type: Article

References (22)

1. Koerber H.R., Mendell L.M. Functional heterogeneity of dorsal root ganglion cells. Scott S.A. Sensory neurons: diversity, development and plasticity. 1992;77-96 Oxford Univ. Press, New York.
2. Djouhri L., Bleazard K., Lawson S.N. Association of somatic action potential shape with sensory receptive properties in guinea-pig dorsal root ganglion neurones. J. Physiol. (Lond.). 513:1998;857-872.
3. Traub R.J., Mendell L.M. The spinal projection of individual identified A-delta- and C-fibers. J. Neurophysiol. 59(1):1988;41-55.
4. Sugiura Y. Spinal organization of C-fiber afferents related to nociception or non-nociception. Kumazawa T., Kruger L., Mizumura K. The polymodal receptor: a gateway to pathological pain. Progress in brain research. vol. 113:1996;319-339 Elsevier, New York.
5. Fitzgerald M., Butcher T., Shortland P. Developmental changes in the laminar termination of A-fiber cutaneous sensory afferents in the rat spinal cord dorsal horn. J. Comp. Neurol. 348:1994;225-233.
6. Coggeshall R.E., Jennings E.A., Fitzgerald M. Evidence that large myelinated primary afferent fibers make synaptic contacts in laminae II of neonatal rats. Dev. Brain Res. 92:1996;81-92.
7. Mirnics K., Koerber H.R. Properties of individual embryonic primary afferents and their spinal projections in the rat. J. Neurophysiol. 78:1997;1590-1600.
8. Ritter A.M., Woodbury C.J., Albers K.M., Davis B.M., Koerber H.R. Maturation of cutaneous sensory neurons from normal and NGF-overexpressing mice. J. Neurophysiol. 83:2000;1722-1732.
9. Woodbury C.J., Ritter A.M., Koerber H.R. Central anatomy of individual rapidly adapting low-threshold mechanoreceptors innervating the "hairy" skin of newborn mice: early maturation of hair follicle afferents. J. Comp. Neurol. 436:2001;304-323.
10. Willis W.D., Coggeshall R.E. Sensory mechanisms of the spinal cord. New York: Plenum; 1991
11. Lawson S.N., McCarthy P.W., Prabhakar E. Electrophysiological properties of neurones with CGRP-like immunoreactivity in rat dorsal root ganglia. J. Comp. Neurol. 365(3):1996;355-366.
12. Koerber H.R., Druzinsky R.E., Mendell L.M. Properties of somata of spinal dorsal root ganglion cells differ according to peripheral receptor innervated. J. Neurophysiol. 60:1988;1584-1596.
13. Ritter A.M., Mendell L.M. Somal membrane properties of physiologically identified sensory neurons in the rat: effects of nerve growth factor. J. Neurophysiol. 68:1992;2033-2041.
14. Ekholm J. Postnatal changes in cutaneous reflexes and in the discharge pattern of cutaneous and articular sense organs: a morphological and physiological study in the cat. Acta Physiol. Scand., Suppl. 297:1967;1-130.
15. Fitzgerald M., Shaw A., MacIntosh N. Postnatal development of the cutaneous flexor reflex: comparative study of preterm infants and newborn rat pups. Dev. Med. Child. Neurol. 30:1988;520-526.
16. Fulton B.P. Postnatal changes in conduction velocity and soma action potential parameters of rat dorsal root ganglion neurones. Neurosci. Lett. 73:1987;125-130.
17. Fitzgerald M., Fulton B.P. The physiological properties of developing sensory neurons. Scott S.A. Sensory neurons: diversity, development and plasticity. 1992;287-306 Oxford Univ. Press, New York.
18. + channels in neurons of the rat dorsal root ganglia. Brain Res. Dev. Brain Res. 65(1):1992;93-100.
19. Woodbury C.J., Negoita F., Davis B.M., Albers K.M., Koerber H.R. Anatomical and functional properties of cutaneous sensory neurons in adult wildtype mice and those overexpressing NGF in the skin. Soc. Neurosci. Abstr. 25:1999;405.
20. Ritter A.M., Woodbury C.J., Zwick M., Davis B.M., Albers K.A., Koerber H.R. Anatomical and physiological properties of cutaneous C-fibers in mice overexpressing GDNF in the skin. Soc. Neurosci. Abstr. 26:2000;845.
21. Koerber H.R., Woodbury C.J., Caterina M.J., Koltzenburg M. Identity of cutaneous sensory neurons containing VRL-1 in wildtype and VR1-KO mice. Soc. Neurosci. Abstr. 27:2001;928.4.
22. Woodbury C.J., Negoita F., Ritter A.M., Koerber H.R. Ectopic projections of myelinated cutaneous fibers following peripheral injury in mice. Soc. Neurosci. Abstr. 26:2000;1213.