Synthesis of new aromatic pyrrolo[2,1-c][1,4]benzodiazepines and pyrrolo[1,2-a]thieno[3,2-e][1,4]diazepines as anti-tumoral agents

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 17, Issue 6, 2002, Pages 403-407

  Lisowski, Vincent ^a   Fabis, Frédéric ^a   Pierre, Alain ^b   Caignard, Daniel Henri ^b   Renard, Pierre ^b   Rault, Sylvain ^a  

^a CENTRE D ETUDES ET DE RECHERCHE SUR LE MÉDICAMENT DE NORMANDIE   (France)

^b ADIR   (France)

Author keywords

Antiproliferative; Aromatization; Leukemia; Pyrrolo 1,2 a thieno 3,2 e 1,4 diazepines; Thieno 2,3 b pyrrolizin 8 ones

Indexed keywords

ANTINEOPLASTIC AGENT; DIAZEPINE DERIVATIVE; PYRROLIZINE DERIVATIVE; PYRROLO[2,1 C][1,4]BENZODIAZEPINE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL GROWTH; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; INHIBITION KINETICS; LEUKEMIA L 1210; PRIORITY JOURNAL;

ANIMALS; ANTINEOPLASTIC AGENTS; BENZENE DERIVATIVES; BENZODIAZEPINES; CELL DIVISION; DRUG SCREENING ASSAYS, ANTITUMOR; INHIBITORY CONCENTRATION 50; ISOMERISM; LEUKEMIA L1210; MICE; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0036949423     PISSN: 14756366     EISSN: None     Source Type: Journal    
DOI: 10.1080/1475636021000005712     Document Type: Article

References (10)

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