Gains and losses of CD8, CD20 and CD56 expression in tumor stroma-infiltrating lymphocytes compared with tumor-associated lymphocytes from ascitic fluid and lymphocytes from tumor draining lymph nodes in serous papillary ovarian carcinoma patients

European Journal of Gynaecological Oncology

Volumn 23, Issue 6, 2002, Pages 533-536

  Papadopoulos, N ^a   Kotini, A ^b   Cheva, A ^b   Jivannakis, T ^b   Manavis, J ^b   Alexiadis, G ^b   Lambropoulou, M ^b   Vavetsis, S ^b   Tamiolakis, D ^b  

^a DEMOCRITUS UNIVERSITY OF THRACE   (Greece)

^b NONE

Author keywords

Ascitic fluid; CD8, CD20, CD56; Serous papillary ovarian carcinoma; Tumor associated lymphocytes; Tumor draining lymph nodes; Tumor infiltrating lymphocytes

Indexed keywords

CD20 ANTIGEN; CD56 ANTIGEN; CD8 ANTIGEN; CELL MARKER; TUMOR ANTIGEN;

ANTIGEN EXPRESSION; ARTICLE; ASCITES FLUID; CANCER CHEMOTHERAPY; CLINICAL ARTICLE; CYTOTOXIC T LYMPHOCYTE; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; LYMPHOCYTE; LYMPHOCYTE DEPLETION; LYMPHOCYTIC INFILTRATION; NATURAL KILLER CELL; OVARY CARCINOMA; PAPILLARY CARCINOMA; TUMOR ASSOCIATED LEUKOCYTE; TUMOR RECURRENCE;

ANTIGENS, CD; ANTIGENS, CD20; ANTIGENS, CD56; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; ASCITES; CYSTADENOCARCINOMA, PAPILLARY; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOPHENOTYPING; LYMPH NODES; LYMPHOCYTES, TUMOR-INFILTRATING; NEOPLASM METASTASIS; OVARIAN NEOPLASMS; PERITONEUM;

EID: 0036944863     PISSN: 03922936     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Piver M. S., Baker T. P., Piedmonte M., Sandecki A. M.: "Epidemiology and etiology of ovarian cancer". Semin. Oncol., 1991, 18, 177.
2. Rose P. G., Piver M. S., Tsukada Y., Lau T. S.: "Metastatic patterns in histologic variants of ovarian cancer: an autopsy study". Cancer, 1989, 64, 1508.
3. Eifel P., Hendickson M., Ross J., Ballon S., Martinez A., Kempson R.: "Simultaneous presentation of carcinoma involving the ovary and the uterine corpus". Cancer, 1982, 50, 163.
4. Kaminski P. F., Norris H. J.: "Coexistence of ovarian neoplasms and endocervical adenocarcinoma. Obstet. Gynecol., 1984, 64, 553.
5. th ed., St Louis, Mosby, 1996, 1461.
6. Blaustein A.: "Peritoneal mesothelium and ovarian surface cells: shared characteristics". Int. J. Gynecol. Pathol., 1981, 3, 361.
7. Foyle A., Al-Jabi M., McGaughey W. T. E.: "Papillary peritoneal tumors in women". Am. J. Surg. Pathol., 1981, 5, 241.
8. Wick M. R., Mills S. E., Dehner L. P., Bollinger D. J., Fechner R. E.: "Serous papillary carcinomas arising from peritoneum and the ovaries: clinicopathologic and immunohistochemical comparison". Int. J. Gynecol. Pathol., 1989, 8, 179.
9. Rao B. R., Slotman B. J.: "Endocrine factors in common epithelial ovarian cancer". Endocr. Rev., 1991, 12, 14.
10. Singer N. G., Todd R. F., Fox D. A.: "Structures on the cell surface. Update from fifth International Workshop on human leucocyte differentiation antigens". Arthritis and Rheumatism, 1994, 37, 1245.
11. Santin A. D., Hermonat P. L., Ravaggi A., Bellone S., Roman J. J., Smith C. V., et al.: "Phenotypic and functional analysis of tumorinfiltrating lymphocytes compared with tumor-associated lymphocytes from ascitic fluid and peripheral blood lymphocytes in patients with advanced ovarian cancer". Gynecol. Obstet. Invest., 2001, 51 (4), 254.
12. Santin A. D., Ravaggi A., Bellone S., Pecorelli S., Cannon M. J., Parham G. P., Hermonat P. L.: "Tumor-infiltrating lymphocytes contain higher numbers of type-1 cytokine expressors and DR+ T cells compared with lymphocytes from tumor draining lymph nodes and peripheral blood in patients with cancer of the uterine cervix". Gynecol. Oncol., 2001, 81 (3), 424.
13. Santin A. D., Bellone S., Ravaggi A., Pecorelli S., Cannon M. J., Parham G. P.: "Induction of ovarian tumor-specific CD8+ cytotoxic T lymphocytes by acid-eluted peptide-pulsed autologous dendritic cells". Obstet. Gynecol., 2000, 96 (3), 422.
14. Santin A. D., Hermonat P. L., Ravaggi A., Bellone S., Cowan C., Korourian S., et al.: "Development, characterization and distribution of adoptively transferred peripheral blood lymphocytes primed by human papillomavirus 18E7-pulsed autologous dendritic cells in a patient with metastatic adenocarcinoma of the uterine cervix". Eur. J. Gynaecol. Oncol., 2000, 21 (1), 17.
15. Baxevanis C. N., Voutsas I. F., Tsitsilonis O. E., Gritzapis A. D., Sotiriadou R., Papamichail M.: "Tumor-specific CD4+ T lymphocytes from cancer patients are required for optimal induction of cytotoxic T cells against the autologous tumor". J. Immunol., 2000, 164 (4), 3902.
16. Santin A. D., Bellone S., Ravaggi A., Roman J. J., Pecorelli S., Parham G. P., Cannon M. J.: "Induction of tumour-specific CD8(+) cytotoxic T lymphocytes by tumour lysate-pulsed autologous dendritic cells in patients with uterine serous papillary cancer". Br. J. Cancer, 2002, 86 (1), 151.
17. Baxevanis C. N., Dedoussis G. V. Z., Papadopoulos N. G., Missitzis I., Stathopoulos G. P., Papamichail M.: "Tumor specific cytolysis by tumor infiltrating lymphocytes in breast cancer". Cancer, 1994, 74, 1275.
18. Baxevanis C. N. G., Dedoussis V. Z., Gritzapis A. D., Stathopoulos G. P., Papamichail M.: "Interleukin-I synergizes with interleukin-2 in the outgrowth of autologous tumor-reactive CD8+ effectors". Br. J. Cancer, 1994, 70, 625.
19. Baxevanis C. N., Papamichail M.: "Characterization of the antitumor immune response in human cancers and strategies for immunotherapy". Crit. Rev. Oncol. Hematol., 1994, 16, 157.
20. Baxevanis C. N., Dedoussis G. V. Z., Papadopoulos N. G., Missitzis I., Beroukas C., Stathopoulos G. R., Papamichail M.: "Enhanced human lymphokine-activated killer cell function after brief exposure to granulocyte-macrophage-colony stimulating factor". Cancer, 1995, 76, 1253.
21. Baxevanis C. N., Tsiatas M. L., Cacoullos N. T., Spanakos G., Liacos C., Missitzis I., et al.: "Induction of anti-tumor lymphocytes in cancer patients after brief exposure to supernatants from cultures of anti-CD3-stimulated allogeneic lymphocytes". Br. J. Cancer, 1997, 76, 1072.
22. Li Y., Bendandi M., Deng Y., Dunbar C., Munshi N., Jagannath S., et al.: "Tumor-specific recognition of human myeloma cells by idiotype-induced CD8+ T cells". Blood, 2000, 96, 2828.
23. Santin A. D., Hermonat P. L., Ravaggi A., Chiriva-Internati M., Zhan D., Pecorelli S., et al.: "Induction of human papillomavirusspecific CD4+ and CDS+ lymphocytes by E7 pulsed autologous dendritic cells in patients with HPV16 and 18 positive cervical cancer". J. Virol., 1999, 73, 5402.
24. Nazaruk R., Rochford M. V., Hobbs and M. J. Cannon: "Functional diversity of the CD8+ T cell response to Epstein-Barr virus (EBV): Implications for the pathogenesis of EBV-associated lymphoproliferative disorders". Blood, 1998, 91, 3875.