-
2
-
-
0033017095
-
Gene gun-mediated IL-12 gene therapy induces antitumor effects in the absence of toxicity: A direct comparison with systemic IL-12 protein therapy
-
Rakhmilevich AL, Timmins JG, Jannssen K, Pohlmann EL, Sheehy MJ, Yang NS (1999) Gene gun-mediated IL-12 gene therapy induces antitumor effects in the absence of toxicity: a direct comparison with systemic IL-12 protein therapy. J Immunother 22:135-144
-
(1999)
J Immunother
, vol.22
, pp. 135-144
-
-
Rakhmilevich, A.L.1
Timmins, J.G.2
Jannssen, K.3
Pohlmann, E.L.4
Sheehy, M.J.5
Yang, N.S.6
-
3
-
-
0028940375
-
In vivo cytokine gene transfer by gene gun reduces tumor growth in mice
-
Sun WH, Burkholder J, Sun J, Clup J, Turner J, Lu XG, Pugh TD, Ershler WB, Yang NS (1995) In vivo cytokine gene transfer by gene gun reduces tumor growth in mice. Proc Natl Acad Sci USA 92:2889-1893
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 2889-1893
-
-
Sun, W.H.1
Burkholder, J.2
Sun, J.3
Clup, J.4
Turner, J.5
Lu, X.G.6
Pugh, T.D.7
Ershler, W.B.8
Yang, N.S.9
-
4
-
-
0029875845
-
Gene gun delivery of mRNA in situ results in efficient transgene expression and genetic immunization
-
Qiu P, Ziegelhoffer PR, Yang NS (1996) Gene gun delivery of mRNA in situ results in efficient transgene expression and genetic immunization. Gene Ther 3:262-268
-
(1996)
Gene Ther
, vol.3
, pp. 262-268
-
-
Qiu, P.1
Ziegelhoffer, P.R.2
Yang, N.S.3
-
5
-
-
0029947820
-
Gene gunmediated skin transfection with interleukin 12 gene results in regression of established primary and metastatic murine tumors
-
Rakhmilevich AL, Turner J, Ford MJ, McCabe D, Sun WH, Sondel PM, Grota K, Yang NS (1996) Gene gunmediated skin transfection with interleukin 12 gene results in regression of established primary and metastatic murine tumors. Proc Natl Acad Sci USA 93:6291
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 6291
-
-
Rakhmilevich, A.L.1
Turner, J.2
Ford, M.J.3
McCabe, D.4
Sun, W.H.5
Sondel, P.M.6
Grota, K.7
Yang, N.S.8
-
6
-
-
0027155874
-
In vivo promotor activity and transgene expression in mammalian somatic tissues evaluated by using particle bombardment
-
Cheng L, Ziegelhoffer PR, Yang NS (1993) In vivo promotor activity and transgene expression in mammalian somatic tissues evaluated by using particle bombardment. Proc Natl Acad Sci USA 90:4455-44559
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 4455-44559
-
-
Cheng, L.1
Ziegelhoffer, P.R.2
Yang, N.S.3
-
7
-
-
1642633622
-
Transfection of mammalian cells by the methods of receptor mediated gene transfer and particle bombardment
-
Novakovik S, Knezevik M, Golouh R, Jezerzek B (1999) Transfection of mammalian cells by the methods of receptor mediated gene transfer and particle bombardment. J Exp Clin Cancer Res 18:531-6
-
(1999)
J Exp Clin Cancer Res
, vol.18
, pp. 531-536
-
-
Novakovik, S.1
Knezevik, M.2
Golouh, R.3
Jezerzek, B.4
-
8
-
-
0031759989
-
Intratumoral coinjection of adenoviral vectors expressing IL-2 and IL12 results in enhanced frequency of regression of injected and untreated distal tumors
-
Addison CL, Bramson JL, Hitt MM, Muller WJ, Gauldie J, Graham FL (1998) Intratumoral coinjection of adenoviral vectors expressing IL-2 and IL12 results in enhanced frequency of regression of injected and untreated distal tumors. Gene Ther 5:1400
-
(1998)
Gene Ther
, vol.5
, pp. 1400
-
-
Addison, C.L.1
Bramson, J.L.2
Hitt, M.M.3
Muller, W.J.4
Gauldie, J.5
Graham, F.L.6
-
9
-
-
0030138921
-
Dual expression of human leukocyte antigen molecules and the B7.1 costimulatory molecule (CD80) on human melanoma cells after particle-mediated gene transfer
-
Albertini MR, Emler CA, Schell K, Tans KJ, King DM, Sheehy MJ (1996) Dual expression of human leukocyte antigen molecules and the B7.1 costimulatory molecule (CD80) on human melanoma cells after particle-mediated gene transfer. Cancer Gene Ther 3:192
-
(1996)
Cancer Gene Ther
, vol.3
, pp. 192
-
-
Albertini, M.R.1
Emler, C.A.2
Schell, K.3
Tans, K.J.4
King, D.M.5
Sheehy, M.J.6
-
10
-
-
0032832478
-
Immunity to breast cancer in mice immunized with X-irradiated breast cancer cells modified to secrete IL-12
-
Carr-Brendel V, Markovic D, Smith M, Tayler-Papadimitriou J, Cohen EP (1999) Immunity to breast cancer in mice immunized with X-irradiated breast cancer cells modified to secrete IL-12. J Immunother 22:415-422
-
(1999)
J Immunother
, vol.22
, pp. 415-422
-
-
Carr-Brendel, V.1
Markovic, D.2
Smith, M.3
Tayler-Papadimitriou, J.4
Cohen, E.P.5
-
11
-
-
0029737924
-
Active immunotherapy of pancreatic cancer with tumor cells genetically engineered to secrete multiple cytokines
-
Clary MB, Coveney EC, Blazer DG, Philip R, Lyerly HK (1996) Active immunotherapy of pancreatic cancer with tumor cells genetically engineered to secrete multiple cytokines. Surgery 120:174
-
(1996)
Surgery
, vol.120
, pp. 174
-
-
Clary, M.B.1
Coveney, E.C.2
Blazer, D.G.3
Philip, R.4
Lyerly, H.K.5
-
12
-
-
0032152332
-
Phase I trial of retroviral vector-mediated interferon (IFN)-gamma gene transfer into autologous tumor cells in patients with metastatic melanoma
-
Nemunaitis J, Bohart C, Fong T, Meyer W, Edelmann G, Paulson RS, Orr D, Jain V, O'Brien J, Kuhn J, Kowal KJ, Burkeholder S, Bruce J, Ognoskie N, Wynne D, Martineau D, Ando D (1998) Phase I trial of retroviral vector-mediated interferon (IFN)-gamma gene transfer into autologous tumor cells in patients with metastatic melanoma. Cancer Gene Ther 5:292-300
-
(1998)
Cancer Gene Ther
, vol.5
, pp. 292-300
-
-
Nemunaitis, J.1
Bohart, C.2
Fong, T.3
Meyer, W.4
Edelmann, G.5
Paulson, R.S.6
Orr, D.7
Jain, V.8
O'Brien, J.9
Kuhn, J.10
Kowal, K.J.11
Burkeholder, S.12
Bruce, J.13
Ognoskie, N.14
Wynne, D.15
Martineau, D.16
Ando, D.17
-
13
-
-
0032842878
-
Selective MHC expression in tumors modulates adaptive and innate antitumor responses
-
Rees RC, Mian S (1999) Selective MHC expression in tumors modulates adaptive and innate antitumor responses. Cancer Immunol Immunother 48:374
-
(1999)
Cancer Immunol Immunother
, vol.48
, pp. 374
-
-
Rees, R.C.1
Mian, S.2
-
14
-
-
0030920608
-
Differential function of CD80- and CD86-transfected human melanoma cells in the presence of IL-12 and IFN-gamma
-
Rudy W, Guckel B, Siebels M, Lindauer M, Meuer SC, Moebius U (1997) Differential function of CD80- and CD86-transfected human melanoma cells in the presence of IL-12 and IFN-gamma. Int Immunol 9:853
-
(1997)
Int Immunol
, vol.9
, pp. 853
-
-
Rudy, W.1
Guckel, B.2
Siebels, M.3
Lindauer, M.4
Meuer, S.C.5
Moebius, U.6
-
15
-
-
2442744586
-
Immunotherapy of metastatic malignant melanoma by a vaccine consisting of autologous interleukin 2-transfected cancer cells: Outcome of a phase I study
-
Schreiber S, Kämpgen E, Wagner E, Pirkhammer D, Trcka J, Korschan H, Lindemann A, Dorffner R, Kittler H, Kastelitz F, Küpcü Z, Sinski A, Zatloukal K, Buschle M, Schmidt W, Birnstiel M, Kempe RE, Voigt T, Weber HA, Pehamberger H, Mertelsmann R, Bröcker EB, Wolff K, Stingl G (1999) Immunotherapy of metastatic malignant melanoma by a vaccine consisting of autologous interleukin 2-transfected cancer cells: outcome of a phase I study. Hum Gene Ther 10:983
-
(1999)
Hum Gene Ther
, vol.10
, pp. 983
-
-
Schreiber, S.1
Kämpgen, E.2
Wagner, E.3
Pirkhammer, D.4
Trcka, J.5
Korschan, H.6
Lindemann, A.7
Dorffner, R.8
Kittler, H.9
Kastelitz, F.10
Küpcü, Z.11
Sinski, A.12
Zatloukal, K.13
Buschle, M.14
Schmidt, W.15
Birnstiel, M.16
Kempe, R.E.17
Voigt, T.18
Weber, H.A.19
Pehamberger, H.20
Mertelsmann, R.21
Bröcker, E.B.22
Wolff, K.23
Stingl, G.24
more..
-
16
-
-
0034105411
-
Antitumor effects on mouse melanoma elicited by local secretion of interleukin-12 and their enhancement by treatment with interleukin-18
-
Nagai H, Hara I, Horikawa T, Fujii M, Kurimoto M, Kamidono S, Ichihasshi M (2000) Antitumor effects on mouse melanoma elicited by local secretion of interleukin-12 and their enhancement by treatment with interleukin-18. Cancer Invest 18:206
-
(2000)
Cancer Invest
, vol.18
, pp. 206
-
-
Nagai, H.1
Hara, I.2
Horikawa, T.3
Fujii, M.4
Kurimoto, M.5
Kamidono, S.6
Ichihasshi, M.7
-
17
-
-
9044245302
-
Interleukin-12 and B7.1 co-stimulation cooperate in the induction of antitumor immunity and therapy of established tumors
-
Zitvogel L, Robbins PD, Storkus WJ, Clarke MR, Maeurer MJ, Campbell RL, Davis CG, Tahara H, Schreiber RD, Lotze MT (1996) Interleukin-12 and B7.1 co-stimulation cooperate in the induction of antitumor immunity and therapy of established tumors. Eur J Immunol 26:1335
-
(1996)
Eur J Immunol
, vol.26
, pp. 1335
-
-
Zitvogel, L.1
Robbins, P.D.2
Storkus, W.J.3
Clarke, M.R.4
Maeurer, M.J.5
Campbell, R.L.6
Davis, C.G.7
Tahara, H.8
Schreiber, R.D.9
Lotze, M.T.10
-
18
-
-
0034114552
-
IL-12 and IL-2-induced tumor regression in a new murine medel of oral squamouscell carcinoma is promoted by expression of the CD80 co-stimulatory molecule and IFN-gamma
-
Thomas GR, Chen Z, Enamorado I, Bancroft C, Van Waes C (2000) IL-12 and IL-2-induced tumor regression in a new murine medel of oral squamouscell carcinoma is promoted by expression of the CD80 co-stimulatory molecule and IFN-gamma. Int J Cancer 86:368
-
(2000)
Int J Cancer
, vol.86
, pp. 368
-
-
Thomas, G.R.1
Chen, Z.2
Enamorado, I.3
Bancroft, C.4
Van Waes, C.5
-
19
-
-
0028340345
-
Induction of specific anti-tumour immunity by interferon-γ gene-transferred murine bladder carcinoma MBT-2
-
Hiura M, Hashimura T, Watanabe Y, Kuribayashi K, Yoshida O (1994) Induction of specific anti-tumour immunity by interferon-γ gene-transferred murine bladder carcinoma MBT-2. Folia Biol 40:49-61
-
(1994)
Folia Biol
, vol.40
, pp. 49-61
-
-
Hiura, M.1
Hashimura, T.2
Watanabe, Y.3
Kuribayashi, K.4
Yoshida, O.5
-
20
-
-
0029268674
-
B7-1 Expression decreases tumorigenicity and induces partial systemic immunity to murine neuroblastoma deficient in major histocompatibility complex and costimulatory molecules
-
Katsanis E, Xu Z, Bausero MA, Dancisak BB, Gorden KB, Davis G, Gray GS, Orchard PJ, Blazar BR (1995) B7-1 Expression decreases tumorigenicity and induces partial systemic immunity to murine neuroblastoma deficient in major histocompatibility complex and costimulatory molecules. Cancer Gene Ther 2:39-46
-
(1995)
Cancer Gene Ther
, vol.2
, pp. 39-46
-
-
Katsanis, E.1
Xu, Z.2
Bausero, M.A.3
Dancisak, B.B.4
Gorden, K.B.5
Davis, G.6
Gray, G.S.7
Orchard, P.J.8
Blazar, B.R.9
-
22
-
-
0031895957
-
Vaccination with IL-12 gene-modified autologus melanoma cells: Clinical results and a first clinical phase I study
-
Sun Y, Jurgovsky K, Moller P, Alijagic S, Dorbic T, Georgieva J, Wittig B, Schadendorf D (1998) Vaccination with IL-12 gene-modified autologus melanoma cells: clinical results and a first clinical phase I study. Gene Ther 5:481
-
(1998)
Gene Ther
, vol.5
, pp. 481
-
-
Sun, Y.1
Jurgovsky, K.2
Moller, P.3
Alijagic, S.4
Dorbic, T.5
Georgieva, J.6
Wittig, B.7
Schadendorf, D.8
-
23
-
-
0032922137
-
In vivo gene therapy with interleukin-12 inhibt primary vascular tumor growth and induces apoptosis in a mouse model
-
Wang C, Quevedo ME, Lannutti BJ, Gordon KB, Guo D, Sun W, Paller AS (1999) In vivo gene therapy with interleukin-12 inhibt primary vascular tumor growth and induces apoptosis in a mouse model. J Invest Dermatol 122:775
-
(1999)
J Invest Dermatol
, vol.122
, pp. 775
-
-
Wang, C.1
Quevedo, M.E.2
Lannutti, B.J.3
Gordon, K.B.4
Guo, D.5
Sun, W.6
Paller, A.S.7
-
25
-
-
0031707741
-
Interleukin-12 is essential for a protective Th1 response in mice infected with Cryptococcus neoformans
-
Decken K, Köhler G, Palmer-Lehmann K, Wunderlich A, Mattner F, Magram, Gately MK, Alber G (1998) Interleukin-12 is essential for a protective Th1 response in mice infected with Cryptococcus neoformans. Infect Immun 66:4994-5000
-
(1998)
Infect Immun
, vol.66
, pp. 4994-5000
-
-
Decken, K.1
Köhler, G.2
Palmer-Lehmann, K.3
Wunderlich, A.4
Mattner, F.5
Magram6
Gately, M.K.7
Alber, G.8
|