BEACH family of proteins: Phylogenetic and functional analysis of six Dictyostelium BEACH proteins

Journal of Cellular Biochemistry

Volumn 86, Issue 3, 2002, Pages 561-570

  Wang, Ning ^a   Wu, Wei I ^a   De Lozanne, Arturo ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

Beige; CHS; Lysosomal traffic; Lyst

Indexed keywords

BEACH PROTEIN; CELL PROTEIN; NEUROBEACHIN; PROTEIN FAN; PROTEIN LYSA; UNCLASSIFIED DRUG;

ARTICLE; CELL FUNCTION; CHEDIAK HIGASHI SYNDROME; CYTOKINESIS; EUKARYOSIS; FUNCTIONAL ASSESSMENT; LYSOSOME; MOLECULAR MODEL; NONHUMAN; NUCLEOTIDE SEQUENCE; OSMOREGULATION; PHENOTYPE; PHYLOGENY; PRIORITY JOURNAL; PROTEIN FAMILY;

AMINO ACID SEQUENCE; ANIMALS; CELL DIVISION; DATABASES, PROTEIN; DICTYOSTELIUM; LYSOSOMES; MOLECULAR SEQUENCE DATA; MUTATION; PHYLOGENY; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; PROTEINS; PROTOZOAN PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; WATER-ELECTROLYTE BALANCE;

DICTYOSTELIUM; EUKARYOTA;

EID: 0036943473     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.10254     Document Type: Article

References (27)

1. Adam-Klages S, Adam D, Weigmann K, Struve S, Kolanus W, Schneider-Mergener J, Kronke M. 1996. FAN, a novel WD-repeat protein, couples the p55 TNF-receptor to neutral sphingomyelinase. Cell 86:937-947.
2. Altschul SF, Madden TL, Schaffer AA, Zhang J, Zhang Z, Miller W, Lipman DJ. 1997. Gapped BLAST and PSIBLAST: A new generation of protein database search programs. Nucleic Acids Res 25:3389-3402.
3. Arnoult D, Tatischeff I, Estaquier J, Girard M, Sureau F, Tissier JP, Grodet A, Dellinger M, Traincard F, Kahn A, Ameisen JC, Petit PX. 2001. On the evolutionary conservation of the cell death pathway: Mitochondrial release of an apoptosis-inducing factor during Dictyostelium discoideum cell death. Mol Biol Cell 12:3016-3030.
4. Barbosa MDFS, Nguyen QA, Tchernev VT, Ashley JA, Detter JC, Blaydes SM, Brandt SJ, Chotai D, Hodgman C, Solari RCE, Lovett M, Kingsmore SF. 1996. Identification of the homologous beige and Chediak-Higashi syndrome genes. Nature 382:262-265.
5. Burns CG, Reedy M, Heuser J, De Lozanne A. 1995. Expression of light meromyosin in Dictyostelium blocks normal myosin II function. J Cell Biol 130:605-612.
6. Cornillon S, Dubois A, Brfickert F, Lefkir Y, Marchetti A, Benghezal M, De Lozanne A, Letourneur F, Cosson P. 2002. Two members of the beige/CHS (BEACH) family are involved at different stages in the organization of the endocytic pathway in Dictyostelium. J Cell Sci 115:737-744.
7. De Lozanne A, Spudich JA. 1987. Disruption of the Dictyostelium myosin heavy chain gene by homologous recombination. Science 236:1086-1091.
8. Gerald N, Damer CK, O'Halloran TJ, De Lozanne A. 2001. Cytokinesis failure in clathrin-minus cells is caused by cleavage furrow instability. Cell Motil Cytoskeleton 48:213-223.
9. Gerald N, Siano M, De Lozanne A. 2002. The Dictyostelium LvsA protein is localized on the contractile vacuole and is required for osmoregulation. Traffic 3:50-60.
10. Han JD, Baker NE, Rubin CS. 1997. Molecular characterization of a novel A kinase anchor protein from Drosophila melanogaster. J Biol Chem 272:26611-26619.
11. Harris E, Wang N, Wu W-I, Weatherford A, De Lozanne A, Cardelli J. 2002. Dictyostelium LvsB mutants model the lysosomal defects associated with Chediak-Higashi syndrome. Mol Biol Cell 13:656-669.
12. Introne W, Boissy RE, Gahl WA. 1999. Clinical, molecular, and cell biological aspects of Chediak-Higashi syndrome. Mol Genet Metab 68:283-303.
13. Kreder D, Krut O, Adam-Klages S, Wiegmann K, Scherer G, Plitz T, Jensen JM, Proksch E, Steinmann J, Pfeffer K, Kronke M. 1999. Impaired neutral sphingomyelinase activation and cutaneous barrier repair in FAN-deficient mice. EMBO J 18:2472-2479.
14. Kwak E, Gerald N, Larochelle DA, Vithalani KK, Niswonger ML, Maready M, De Lozanne A. 1999. LvsA, a protein related to the mouse beige protein, is required for cytokinesis in Dictyostelium. Mol Biol Cell 10:4429-4439.
15. Larochelle DA, Vithalani KK, De Lozanne A. 1997. The role of Dictyostelium race in cytokinesis: Mutational analysis and localization studies by use of green fluorescent protein. Mol Biol Cell 8:935-944.
16. Manstein DJ, Titus MA, De Lozanne A, Spudich JA. 1989. Gene replacement in Dictyostelium: Generation of myosin null mutants. EMBO J 8:923-932.
17. McVey Ward D, Griffiths GM, Stinchcombe JC, Kaplan J. 2000. Analysis of the lysosomal storage disease ChediakHigashi syndrome. Traffic 1:816-822.
18. Nagle DL, Karim MA, Woolf EA, Holmgren L, Bork P, Misumi DJ, McGrail SH, Dussault BJ, Perou CM, Boissy RE, Duyk GM, Spritz RA, Moore KJ. 1996. Identification and mutation analysis of the complete gene for ChediakHigashi syndrome. Nat Genet 14:307-311.
19. Perou CM, Moore KJ, Nagle DL, Misumi DJ, Woolf EA, McGrail SH, Holmgren L, Brody TH, Dussault BJ, Monroe CA, Duyk GM, Pryor RJ, Li L, Justice MJ, Kaplan J. 1996. Identification of the murine beige gene by YAC complementation and positional cloning. Nat Genet 13:303-308.
20. Segui B, Andrieu-Abadie N, Adam-Klages S, Meilhac O, Kreder D, Garcia V, Bruno AP, Jaffrezou JP, Salvayre R, Kronke M, Levade T. 1999. CD40 signals apoptosis through FAN-regulated activation of the sphingomyelinceramide pathway. J Biol Chem 274:37251-37258.
21. Sussman M. 1987. Cultivation and synchronous morphogenesis of Dictyostelium under controlled experimental conditions. In: Spudich JA, editor. Dictyostelium Discoideum: Molecular Approaches to Cell Biology. New York: Academic Press, Inc. pp 9-29.
22. Sutoh K. 1993. A transformation vector for Dictyostelium discoideum with a new selectable marker bsr. Plasmid 30:150-154.
23. Vithalani KK, Parent C, Thorn EM, Penn M, Larochelle DA, Devreotes PN, De Lozanne A. 1998. Identification of Darlin, a Dictyostelium protein with armadillo-like repeats that binds to small GTPases and is important for the proper aggregation of developing cells. Mol Biol Cell 8:3095-3106.
24. Vithalani KK, Shoffner JD, De Lozanne A. 1996. Isolation and characterization of a novel cytokinesis-deficient mutant in Dictyostelium discoideum. J Cell Biochem 62:290-301.
25. Wang JW, Howson J, Haller E, Kerr WG. 2001. Identification of a novel lipopolysaccharide-inducible gene with key features of both A kinase anchor proteins and chs1/beige proteins. J Immunol 166:4586-4595.
26. Wang X, Herberg FW, Laue MM, Wullner C, Hu B, Petrasch-Parwez E, Kilimann MW. 2000. Neurobeachin: A protein kinase A-anchoring, beige/Chediak-higashi protein homolog implicated in neuronal membrane traffic. J Neurosci 20:8551-8565.
27. Winzeler EA, Shoemaker DD, Astromoff A, Liang H, Anderson K, Andre B, Bangham R, Benito R, Boeke JD, Bussey H, Chu AM, Connelly C, Davis K, Dietrich F, Dow SW, El Bakkoury M, Foury F, Friend SH, Gentalen E, Giaever G, Hegemann JH, Jones T, Laub M, Liao H, Davis RW. et al. 1999. Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis. Science 285:901-906.