Disparate effects of chronic and acute theophylline on cyclosporine A nephrotoxicity

Pediatric Nephrology

Volumn 17, Issue 6, 2002, Pages 418-424

  Prévot, Anne ^a,b   Liet, Jean Michel ^b,c   Semama, Denis S ^b   Justrabo, Eve ^b   Guignard, Jean Pierre ^a   Gouyon, Jean Bernard ^b  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^b DIJON UNIVERSITY HOSPITAL   (France)

^c Hopital Mere Enfant CHU de Nantes   (France)

Author keywords

Acute renal failure; Adenosine; Cyclosporine A; Kidney; Nephrotoxicity; Rabbit; Theophylline

Indexed keywords

ADENOSINE; ADENOSINE RECEPTOR BLOCKING AGENT; CYCLOSPORIN A; SANDIMMUM; THEOPHYLLINE;

ACUTE KIDNEY FAILURE; ACUTE TOXICITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY CONSTRICTION; ARTICLE; CHRONIC TOXICITY; CONTROLLED STUDY; DIURESIS; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG INFUSION; GLOMERULUS FILTRATION RATE; KIDNEY BLOOD FLOW; KIDNEY FUNCTION; KIDNEY VASCULAR RESISTANCE; MALE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RABBIT; RENAL SYSTEM PARAMETERS;

ANIMALS; CYCLOSPORINE; DRUG ADMINISTRATION SCHEDULE; GLOMERULAR FILTRATION RATE; IMMUNOSUPPRESSIVE AGENTS; KIDNEY FAILURE, ACUTE; MALE; RABBITS; RECEPTORS, PURINERGIC P1; THEOPHYLLINE;

EID: 0036939731     PISSN: 0931041X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00467-002-0842-1     Document Type: Article

References (33)

1. Curtis JJ, Luke RG, Dubovsky E, Diethelm AG, Whelchel JD, Jones P (1986) Cyclosporin in therapeutic doses increases renal allograft vascular resistance. Lancet 2:477-479
2. Kaskel FJ, Devarajan P, Arbeit LA, Partin JS, Moore LC (1987) Cyclosporine nephrotoxicity; sodium excretion, auto-regulation and angiotensin II. Am J Physiol 252:F733-F742
3. Thliveris JA, Yatscoff RW, Lukowski MP, Copeland KR, Jeffery JR, Murphy GF (1991) Chronic ciclosporin nephrotoxicity: a rabbit model. Nephron 57:470-476
4. Thliveris JA, Solez K, Yatscoff RW (1995) A comparison of the effects of rapamycin and cyclosporine on kidney and heart morphology in a rabbit heterotopic heart transplant model. Histol Histopathol 10:417-421
5. Andoh TF, Lindsley J, Franceschini N, Bennett WM (1996) Synergistic effects of cyclosporine and rapamycin in a chronic nephrotoxicity model. Transplantation 62:311-316
6. Bisogno G, Cowie F, Boddy A, Thomas HD, Dick G, Pinkerton CR (1998) High-dose cyclosporin with etoposide: toxicity and pharmacokinetic interaction in children with solid tumours. Br J Cancer 77:2304-2309
7. Prévot A, Semama DS, Tendron A, Justrabo E, Guignard J-P Gouyon J-B (2000) Endothelin, angiotensin II and adenosine in acute cyclosporine A-induced nephrotoxicity. Pediatr Nephrol 14:927-934
8. Guieu R, Dussol B, Devaux C, Sampol J, Brunet P, Rochat H, Bechis G, Berland YF (1998) Interactions between cyclosporine A and adenosine in kidney transplant recipients. Kidney Int 53:200-204
9. Halimi G, Sampol J, Clot-Faybesse O, Mercier L, Devaux C, Berland Y, Dussol B, Rochat H, Guieu R (1999) Cyclosporine A and purininergic receptors in rat kidney. Life Sci 65:2810-2813
10. Bakris GL, Burnett JC (1985) Theophylline attenuates radio-contrast-induced intrarenal vasoconstriction. Kidney Int 27:227
11. Katholi RE, Taylor GJ, McCann WP, Woods WT, Womack KA, McCoy CD, Katholi CR, Moses HW, Mishkel GJ, Lucore CL, Holloway RM, Miller BD, Woodruff RC, Dove JT, Mikell FL, Schneider JA (1995) Nephrotoxicity from contrast media: attenuation with theophylline. Radiology 195:17-22
12. Heidemann HT, Gerkens JF, Jackson EK, Branch RA (1983) Effect of aminophylline on renal vasoconstriction produced by amphotericin B in the rat. Naunyn Schmiedebergs Arch Pharmacol 324:148-152
13. Lin JJ, Churchill PC, Bidani AK (1986) Effect of theophylline on the initiation phase of postischemic acute renal failure in rats. J Lab Clin Med 108:150-154
14. Bidani AK, Churchill PC, Packer W (1987) Theophylline-induced protection in myoglobinuric acute renal failure: further characterization. Can J Physiol Pharmacol 65:42-45
15. Gouyon J-B, Guignard J-P (1988) Theophylline prevents the hypoxemia-induced renal hemodynamic changes in rabbits. Kidney Int 33:1078-1083
16. Fandrey J, Rob PM, Jelkmann W (1991) Theophylline and magnesium inhibit the contraction elicited with ciclosporin and angiotensin II in mesangial cell cultures. Nephron 57:94-98
17. Potier M, Lakhdar B, L'Azou B, Cambar J (1995) Evidence for a protective effect of theophylline and caffeine on cyclosporine-induced contractions in two in vitro glomerular models. Transplant Proc 27:2492-2494
18. Gerkens JF, Smith AJ (1985) Effect of captopril and theophylline treatment on cyclosporine-induced nephrotoxicity in rats. Transplantation 40:213-214
19. Churchill PC, Rossi NF, Churchill MC, Bidani AK, McDonald FD (1990) Acute cyclosporine-induced renal vasoconstriction: lack of effect of theophylline. Am J Physiol 258:F41-F45
20. Prévot A, Semama DS, Justrabo E, Guignard J-P, Escousse A and Gouyon J-B (2000) Acute cyclosporine A-induced nephrotoxicity: a rabbit model. Pediatr Nephrol 14:370-375
21. Wright HK, Gann DS (1966) An automatic method for determination of inulin in plasma and urine. J Lab Clin Med 67:689-693
22. Bratton AC, Marshall EK (1939) A new coupling component for sulfanilamide determination. J Biol Chem 128:537-550
23. Prada J, Churchill P, Bidani A (1986) Protective effect of theophylline in endotoxin-mediated acute renal failure in rats. Kidney Int 29:308
24. Huet F, Semama D, Grimaldi M, Guignard J-P, Gouyon J-B (1995) Effects of theophylline on renal insufficiency in neonates with respiratory distress syndrome. Intensive Care Med 21:511-514
25. Hall J, Granger JP, Hester RL (1985) Interactions between adenosine and angiotensin II in controlling glomerular filtration. Am J Physiol 248:F340-F346
26. Weihprecht H, Lorenz JN, Briggs JP, Schnermann J (1994) Synergistic effects of angiotensin and adenosine in the renal microvasculature. Am J Physiol 266:F227-F239
27. Murray RD, Churchill PC (1984) Effects of adenosine receptor agonists in the isolated perfused kidney. Am J Physiol 16:H343-H348
28. 2-receptor agonists on intrarenal blood flow. Am J Physiol 265:F802-F806
29. Balakrishnan VS, Coles GA, Williams JD (1993) A potential role for endogenous adenosine in control of human glomerular and tubular function. Am J Physiol 265:F504-F510
30. Fransen R, Koomans HA (1995) Adenosine and renal sodium handling: direct natriuresis and renal nerve-mediated antinatriuresis. J Am Soc Nephrol 6:1491-1497
31. Fuhr U, Doehmer J, Battula N, Wölfel C, Kudla C, Keita Y, Staib AH (1992) Biotransformation of caffeine and theophylline in mammalian cell lines genetically engineered for expression of single cytochrome P450 isoforms. Biochem Pharmacol 43:225-235
32. Boubenider S, Vincent I, Lambotte O, Roy S, Hiesse C, Taburet AM, Charpentier B (2000) Interaction between theophylline and tacrolimus in a renal transplant patient. Nephrol Dial Transplant 15:1066-1068
33. Rall TW (1992) Chapter 25. In: Goodman and Gilman's the pharmacological basis of therapeutics, 6th edn. Macmillan Publishing Co, New York, pp 626-628