Novel synthesis of benzo[a]quinolizines (pyrido[2,1-a]isoquinolines) by [3+3]-cyclocondensation of 1-alkyl-3,4-dihydroisoquinolines with β-ketoesters

Chemistry of Natural Compounds

Volumn 38, Issue 6, 2002, Pages 598-601

  Gulyakevich, O V ^a   Kurman, P V ^a   Mikhal'Chuk, A L ^a  

^a INSTITUTE OF BIOORGANIC CHEMISTRY   (Belarus)

Author keywords

1 alkyl 3,4 dihydroisoquinoline; Acetoacetic and 2 benzylacetoacetic esters; Benzo a quinolizine (pyrido 2,1 a isoquinoline); Synthesis

Indexed keywords

EID: 0036938455     PISSN: 00093130     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1022607325613     Document Type: Article

References (7)

1. W. Wiegrebe, W. J. Kramer, and M. Shamma, J. Nat. Prod., 47, 397 (1984).
2. H. O. Bernhard and V. A. Sniieckus, Alkaloids (London), 2, 97 (1972).
3. J. R. Huff, P. S. Anderson, J. J. Baldwin, B. V. Clinesschmidt, J. P. Guare, V. J. Lotti, D. J. Pettibone, W. C. Randale, and J. P. Vacca, J. Med. Chem., 28, No. 12, 1756 (1985).
4. O. V. Gulyakevich and A. L. Mikhal'chuk, Dokl. Akad. Nauk, 345, No. 6, 776 (1995).
5. A. L. Mikhal'chuk, O. V. Gulyakevich, and A. A. Akhrem, Khim. Geterotsikl. Soedin., No. 2, 235 (1996).
6. O. V. Gulyakevich and A. L. Mikhal'chyk, Zh. Obshch. Khim., 66, 163 (1996).
7. O. V. Gulyakevich and A. L. Mikhal'chuk, Khim. Prir. Soedin., 432 (1997).