Sperm mediated transgenesis rushes 'back to the future'

Molecular Therapy

Volumn 6, Issue 6, 2002, Pages 699-700

  Cibelli, Jose B ^a  

^a Advanced Cell Technology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CLASSICAL COMPLEMENT PATHWAY C3 C5 CONVERTASE; DECAY ACCELERATING FACTOR; DNA; GENOMIC DNA; MESSENGER RNA; PLASMID DNA;

ARTICLE; ARTIFICIAL INSEMINATION; CELL CLONING; CELL NUCLEUS TRANSPLANTATION; COMPLEMENT ACTIVATION; DNA BINDING; DNA RECOMBINATION; DNA TRANSFER; EMBRYOLOGY; FERTILIZATION; GENETIC TRANSCRIPTION; HISTOCOMPATIBILITY COMPLEX; HUMAN; MICROINJECTION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA TRANSLATION; SOMATIC CELL; SPERM; SPERM DONOR; TRANSGENIC ANIMAL; TRANSGENICS;

ANIMALIA; JUNCUS;

EID: 0036932849     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1006/mthe.2002.0819     Document Type: Editorial

References (5)

1. Lavitrano, M., Bacci, M. L., Forni, M., et al. (2002). Efficient production by sperm-mediated gene transfer of human decay accelerating factor (hDAF) transgenic pigs for xenotransplantation. Proc. Natl. Acad. Sci. USA 99: 14230-14235.
2. Sun, X., Funk, C. D., Deng, C., Sahu, A., Lambris, J. D., and Song, W. C. (1999). Role of decay-accelerating factor in regulating complement activation on the erythrocyte surface as revealed by gene targeting. Proc. Natl. Acad. Sci. USA 96: 628-633.
3. Wall, R. J. (2002). New gene transfer methods. Theriogenology 57: 189-201.
4. Spadafora, C. (1998). Sperm cells and foreign DNA: a controversial relation. Bioessays 20: 955-964.
5. Lavitrano, M., Maione, B., Forte, E., et al. (1997). The interaction of sperm cells with exogenous DNA: a role of CD4 and major histocompatibility complex class II molecules. Exp. Cell Res. 233: 56-62.