Determination of vigabatrin in tablets by high performance liquid chromatography

Acta Pharmaceutica Turcica

Volumn 44, Issue 2, 2002, Pages 57-62

  Çetin, Sevil Müge ^a   Atmaca, Sedef ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

Author keywords

1,2 naphthoquinone 4 sulfonic acid sodium salt; High performance liquid chromatography; Vigabatrin

Indexed keywords

1,2 NAPHTHOQUINONE 4 SULFONIC ACID DERIVATIVE; 1,2 NAPHTHOQUINONE DERIVATIVE; ASPARTAME DERIVATIVE; UNCLASSIFIED DRUG; VIGABATRIN;

ARTICLE; DRUG DETERMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SIGNAL NOISE RATIO; TABLET; ULTRAVIOLET SPECTROPHOTOMETRY;

EID: 0036930758     PISSN: 1300638X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Al-Zehouri, J., Al-Madi, S., Belal, F. (2001). Determination of the antiepileptics vigabatrin and gabapentin in dosage forms and biological fluids using Hantzsch reaction. Arzneimittel-Forschung, 51: 97-103.
2. Belal, F., Abdine, A., Al-Majed, A., Khalil, N.Y. (2002). Spectrofluorimetric determination of vigabatrin and gabapentin in urine and dosage forms through derivatization with fluorescamine. J. Pharm. Biomed. Anal. 27: 253-260.
3. Chen, T.M., Contario, J.J., Fike, R.R.(1987). High-performance liquid chromatographic assay for vigabatrin and its primary degradation product in a pharmaceutical tablet formulation. J. Chromatogr. 398: 351-354.
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6. Olgun, N., Erturk, S., Atmaca, S. (2002). Spectrofluorimetric and spectrophotometric methods for the determination of vigabatrin in tablets. J. Pharm. Biomed. Anal. 29: 1-5.
7. Riekkinen, P.J., Pitkanen, A., Ylinen, A., Sivenius, J., Halonen, T. (1989). Specificity of vigabatrin for the GABAergic system in human epilepsy. Epilepsia, 30 (Suppl.3): 18-22.