Testing for nandrolone metabolites in urine samples of professionals athletes and sedentary subjects by GC/MS/MS analysis

Biomedical Chromatography

Volumn 16, Issue 8, 2002, Pages 508-512

  Gambelunghe, Cristiana ^a   Sommavilla, Marco ^a   Rossi, Ruggero ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMOLECULES; BODY FLUIDS; PROFESSIONAL ASPECTS;

ANABOLIC STEROID; ANALYTICAL APPROACH; GC/MS/MS; LOW DETECTION LIMIT; MS/MS ANALYSIS; NANDROLONE; PHYSICAL ACTIVITY; QUALITATIVE AND QUANTITATIVE ANALYSIS; URINARY METABOLITES; URINE SAMPLE;

METABOLITES;

19 NORANDROSTERONE; 19 NORETIOCHOLANOLONE; NANDROLONE DERIVATIVE; SEX HORMONE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; ATHLETE; CONTROLLED STUDY; FOOTBALL; GAS CHROMATOGRAPHY; HORMONE URINE LEVEL; HUMAN; MALE; NORMAL HUMAN; PHYSICAL ACTIVITY; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; SITTING; TANDEM MASS SPECTROMETRY; URINALYSIS;

EID: 0036929760     PISSN: 02693879     EISSN: None     Source Type: Journal    
DOI: 10.1002/bmc.193     Document Type: Article

References (13)

1. Botrè F and Tranqulli C. Atti del convegno: 'Esposizione e confini al supporto ergogenico: limiti e rischi nell'uso degli integratori. Uso e diffusione degli integratori in Italia. Opinioni a confronto. Medicina dello Sport 2001; 54: 263.
2. Catlin DH, Leder BZ, Ahrens B, Starcevic B, Hatton CK, Green GA and Finkelstein JS. Trace contamination over-the-counter androstenedione and positive urine test results for a nandrolone metabolite. JAMA 2000: 284: 2618.
3. Debruyckere G, de Sangher R, De Leenheer C and Van Peterghem C. Proceeding of the 4th Symposium on the analysis of steroids, Budapest, Gorog S (ed.), 1991; 363.
4. De Cock KJS, Delbeke FT, Van Eenoo PV, Desmet N, Roels K and De Backer P. Detection and determination of anabolic steroids in nutritional supplements. Journal of Pharmaceutical and Biomedical Analysis 2001: 25: 843.
5. Galán Martin AM. Maynar Mariòo JL, Garcia de Tiedra MP, Rivero Marabé JJ, Caballero Loscos MJ and Maynar M. Determination of nandrolone and metabolites in urine samples from sedentary persons and sportsmen. Journal of Chromatography B 2001; 761: 229.
6. Kamber M, Baume N and Rivier L. Nutritional supplements as a source for positive doping cases. International Journal of Sport, Nutrition and Exercise Metabolism 2001; 11: 258.
7. Kintz P, Ciremele V and Ludes B. Norandrostenolone and noretiocholanolone: metabolite markers. Acta Clinica Belgique Supplement 1999; 1: 68.
8. Kintz P, Cirimele V, Dumestre-Toulet V and Ludes B. Doping control for nandrolone using hair analysis. Journal of Pharmaceutical and Biomedical Analysis 2001; 24: 1125.
9. Le Bizec B, Monteau F. Gaudin I and Andrè F. Evidence for the presence of endogenous 19-norandrosterone in human urine. Journal of Chromatography B 1999: 723: 157.
10. Le Bizec B, Gaudin I, F. Monteau F, Andre F and Impens F et al. Consequence of boar edible tissue consuption on urinary profiles of nandrolone metabolites. I. Mass spectrometric detection and quantification of 19-norandrosterone and 19-noretiocholanolone in human urine. Rapid Communications on Mass Spectrometry, 2000: 14: 1058.
11. Muñoz-Guerra J, Carreras D. Soriano C. Rodríguez A. Rodríguez F. Use of ion trap gas chromatography-tandem mass spectrometry for detection and confirmation of anabolic substances at trace levels in doping analysis. Journal of Chromatography B 1997; 704: 129.
12. Ozer D and Temizer A. The determination of nandrolone and its metabolites in urine by gas chromatography-mass spectrometry. European Journal of Drug Metabolism and Pharmacokinetics 1997; 22: 421.
13. Robinson N, Taroni F, Saugy M, Ayotte C, Mangin P and Dvorak J. Detection of nandrolone metabolites in urine after a football game in professional and amateur players: a Bayesian comparison. Forensic Science International 2001. 122: 130.