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Evidence Based Medicine Instruction
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Rapacuronium and the risk of bronchospasm in pediatric patients
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Rajchert DM, Pasquariello CA, Watcha MF, Schreiner MS. Rapacuronium and the risk of bronchospasm in pediatric patients. Anesth Analg 2002; 94:488-493. An outstanding illustration of the use of an automated anesthesia record keeping system to perform case-control and cohort studies.
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Rajchert, D.M.1
Pasquariello, C.A.2
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Rapacuronium redux
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Schulman SR. Rapacuronium redux. Anesth Analg 2002; 94:483-484. This study discusses relative risks, odds ratios and their interpretation.
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Schulman, S.R.1
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Developing optimal search strategies for dectecting clinically sound studies in MEDLINE
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Haynes, R.B.1
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Users' guides to the medical literature. II. How to use an article about therapy or prevention. A. Are the results of the study valid?
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Guyatt GH, Sackett DL, Cook DJ. Users' guides to the medical literature. II. How to use an article about therapy or prevention. A. Are the results of the study valid? JAMA 1993; 270:2598-2601.
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Guyatt, G.H.1
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Cook, D.J.3
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10
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0028047157
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Users' guides to the medical literature. II. How to use an article about therapy or prevention. B. What were the results and will they help me in caring for my patients?
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Guyatt GH, Sackett DL, Cook DJ. Users' guides to the medical literature. II. How to use an article about therapy or prevention. B. What were the results and will they help me in caring for my patients? JAMA 1994; 271:59-63.
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Guyatt, G.H.1
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Surrogate end points in clinical trials: Are we being misled?
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Preliminary report: Effect of encainide and flecainide on mortality in a randomized trial of arrhythmia suppression after myocardial infarction
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Cardiac Arrhythmia Suppression Trial (CAST) Investigators. Preliminary report: Effect of encainide and flecainide on mortality in a randomized trial of arrhythmia suppression after myocardial infarction. N Engl J Med 1989; 321:406-412.
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Surrogate outcomes: Meaningful not!
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Fisher DM. Surrogate outcomes: Meaningful not! Anesthesiology 1999; 90:355-356.
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Fisher, D.M.1
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Anesthesiologist board certification and patient outcomes
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Silber JH, Kennedy SK, Even-Shoshan O, et al. Anesthesiologist board certification and patient outcomes. Anesthesiology 2002; 96:1044-1052. An article illustrating the use of administrative databases in true outcomes-based research. The results have vital implications for the specialty.
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Anesthesiology
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Silber, J.H.1
Kennedy, S.K.2
Even-Shoshan, O.3
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Outcomes in perioperative medicine and anesthesiology
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Wu CL, Fleischer LA. Outcomes in perioperative medicine and anesthesiology. Anesth Clin North Am 2000; 18:633-645.
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Wu, C.L.1
Fleischer, L.A.2
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Users' guides to the medical literature. XIII. How to use an article on economic analysis of clinical practice. A. Are the results of the study valid?
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Drummond MF, Richardson WS, O'Brien BJ, et al. Users' guides to the medical literature. XIII. How to use an article on economic analysis of clinical practice. A. Are the results of the study valid? JAMA 1997; 277:1552-1557.
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Drummond, M.F.1
Richardson, W.S.2
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Users' guides to the medical literature. XIII. How to use an article on economic analysis of clinical practice. B. What are the results and will they help me in caring for my patients?
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O'Brien BJ, Heyland D, Richardson WS, et al. Users' guides to the medical literature. XIII. How to use an article on economic analysis of clinical practice. B. What are the results and will they help me in caring for my patients? JAMA 1997; 277:1802-1806.
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O'Brien, B.J.1
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0035127120
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Examining the evidence in anesthesia literature: A critical appraisal of systematic reviews
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Choi PTL, Halpern SH, Malik N, et al. Examining the evidence in anesthesia literature: A critical appraisal of systematic reviews. Anesth Analg 2001; 92:700-709. This study summmarizes the state of the art in anesthesia systematic reviews. A review of the reviews.
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Anesth Analg
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Choi, P.T.L.1
Halpern, S.H.2
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Measuring anaesthetic outcomes
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Lee A, Lurn ME. Measuring anaesthetic outcomes. Anaesth Intens Care 1996; 24:685-693.
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Lee, A.1
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The development of evidence-based clinical practice guidelines. Integrating medical science and practice
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Connis RT, Nickinovich DG, Caplan RA, Arens JF. The development of evidence-based clinical practice guidelines. Integrating medical science and practice. Int J Technol Assess Health Care 2000; 16:1003-1012.
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Connis, R.T.1
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Arens, J.F.4
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A new system for grading recommendations in evidence based guidelines
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Harbour R, Miller J. A new system for grading recommendations in evidence based guidelines. BMJ 2001; 323:334-336.
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A quantitative, systematic review of randomized controlled trials of ephedrine versus phenylephrine for the management of hypotension during spinal anesthesia for cesarean delivery
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Lee A, Ngan K, Warwick D, Gin T. A quantitative, systematic review of randomized controlled trials of ephedrine versus phenylephrine for the management of hypotension during spinal anesthesia for cesarean delivery. Anesth Analg 2002; 94:920-926. Meta-analysis meets obstetric anesthesia.
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Lee, A.1
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Warwick, D.3
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Intrathecal opioids versus epidural local anesthetics for labor analgesia: A meta analysis
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Bucklin BA, Chestnut DH, Hawkins JL. Intrathecal opioids versus epidural local anesthetics for labor analgesia: A meta analysis. Reg Anesth Pain Med 2002; 27:23-30. Pruritis is more common with intrathecal opioids.
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Reg Anesth Pain Med
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Bucklin, B.A.1
Chestnut, D.H.2
Hawkins, J.L.3
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25
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0035145442
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Evaluation of the effective drugs for the prevention of nausea and vomiting induced by morphine used for postoperative pain: A quantitative systematic review
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Hirayama T, Ishii F, Yago K, Ogata H. Evaluation of the effective drugs for the prevention of nausea and vomiting induced by morphine used for postoperative pain: A quantitative systematic review. Yakugaku Zasshi - J Pharm Soc Japan 2001; 121:179-185.
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Hirayama, T.1
Ishii, F.2
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Pharmacological treatment of postoperative shivering: A quantitative systematic review of randomized controlled trials
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Kranke P, Eberhart L, Roewer N, Tramer MR. Pharmacological treatment of postoperative shivering: A quantitative systematic review of randomized controlled trials. Anesth Analg 2002; 94:453-460. A comparison of three treatment regimens for this common post-anesthetic problem.
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Anesth Analg
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Kranke, P.1
Eberhart, L.2
Roewer, N.3
Tramer, M.R.4
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27
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0035076456
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A lack of evidence of superiority of propofol versus midazolam for sedation in mechanically ventilated critically ill patients: A qualitative and quantitative systematic review
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Walder B, Elia N, Henzi I, et al. A lack of evidence of superiority of propofol versus midazolam for sedation in mechanically ventilated critically ill patients: A qualitative and quantitative systematic review. Anesth Analg 2001; 92:975-983.
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Anesth Analg
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Walder, B.1
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Trials of corticosteroids to prevent postextubation airway complications
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Meade MO, Guyatt GH, Cook DJ, et al. Trials of corticosteroids to prevent postextubation airway complications. Chest 2001; 120 (Suppl.):464S-468S. An important summary of a therapy commonly used but not entirely supported by evidence. Illustrates the use of surrogate endpoints in clinical trials. Highlights some differences between pediatric and adult trials.
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Chest
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Meade, M.O.1
Guyatt, G.H.2
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Epidural analgesia reduces postoperative myocardial infarction: A meta-analysis
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Beattie WS, Badner NH, Choi P. Epidural analgesia reduces postoperative myocardial infarction: A meta-analysis. Anesth Analg 2001; 93:853-858. This study nicely summarizes the existing literature on the regional versus general controversy.
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Anesth Analg
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Beattie, W.S.1
Badner, N.H.2
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Reduction of postoperative mortality and morbidity with epidural or spinal anaesthesia: Results from overview of randomized trials
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Rogers A, Walker N, Schug S, et al. Reduction of postoperative mortality and morbidity with epidural or spinal anaesthesia: Results from overview of randomized trials. BMJ 2000; 321:1493-1497.
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Does perioperative myocardial ischemia lead to postoperative myocardial infarction?
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Changes in anesthesiology practice are explicated
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Torpy JM. Changes in anesthesiology practice are explicated. JAMA 2002; 287:1924-1926.
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JAMA
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Torpy, J.M.1
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