cAMP pathway alterations from the cell surface to the nucleus in adrenocortical tumors

Endocrine Research

Volumn 28, Issue 4, 2002, Pages 765-775

  Rosenberg, Dan ^a   Groussin, Lionel ^a   Bertagna, Xavier ^a   Bertherat, Jérôme ^a  

^a INSTITUT COCHIN   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOTROPIN; CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GASTRIC INHIBITORY POLYPEPTIDE;

ADRENAL CORTEX ADENOMA; ADRENAL CORTEX TUMOR; CELL SURFACE; CONFERENCE PAPER; CUSHING SYNDROME; HUMAN; HUMAN CELL; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

EID: 0036922022     PISSN: 07435800     EISSN: None     Source Type: Journal    
DOI: 10.1081/ERC-120017071     Document Type: Conference Paper

References (10)

1. Roger, P.P.; Reuse, S.; Maenhaut, C.; Dumont, J.E. Multiple facets of the modulation of growth by cAMP. Vitam. Horm. 1995, 51, 59-191.
2. Bertherat, J. Nuclear effects of the cAMP pathway activation in somatotrophs. Horm. Res. 1997, 47, 245-250.
3. Simpson, E.R.; Waterman, M.R. Regulation of the synthesis of steroidogenic enzymes in adrenal cortical cells by ACTH. Annu. Rev. Physiol. 1988, 50, 427-440.
4. Struthers, R.S.; Vale, W.W.; Arias, C.; Sawchenko, P.E.; Montminy, M.R. Somatotroph hypoplasia and dwarfism in transgenic mice expressing a non-phosphorylatable CREB mutant. Nature 1991, 350, 622-624.
5. Nguyen, L.; Kopp, P.; Martinson, E; Stanfield, K.; Roth, S.; Jameson, J. A dominant negative CREB (cAMP response element-binding protein) isoform inhibits thyrocyte growth, thyroid-specific gene expression, differentiation, and function. Mol. Endocrinol. 2000, 14, 1448-1461.
6. Parma, J.; Duprez, L.; Van Sande, J.; Cochaux, P.; Gervy, C.; Mockel, J. et al. Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas. Nature 1993, 365, 649-651.
7. Landis, C.A.; Masters, S.B.; Spada, A.; Pace, A.M.; Bourne, H.R.; Vallar, L. GTPase inhibiting mutations activate the alpha chain of Gs and stimulate adenylyl cyclase in human pituitary tumours. Nature 1989, 340, 692-696.
8. Weinstein, L.S.; Shenker, A.; Gejman, P.V.; Merino, M.J.; Friedman, E.; Spiegel, A.M. Activating mutations of the stimulatory G protein in the McCune-Albright syndrome. N. Engl. J. Med. 1991, 325, 1688-1695.
9. Lacroix, A.; Ndiaye, N.; Tremblay, J.; Hamet, P. Ectopic and abnormal hormone receptors in adrenal Cushing's syndrome. Endocr. Rev. 2001, 22 (1), 75-110.
10. Kirschner, L.S.; Sandrini, E; Monbo, J.; Lin, J.P.; Carney, J.A.; Stratakis, C.A. Genetic heterogeneity and spectrum of mutations of the PRKAR1A gene in patients with the carney complex. Hum. Mol. Genet. 2000, 9 (20), 3037-3046.