Investigations on osmotic matrix tablets as controlled delivery systems of ketorolac tromethamine

Acta Pharmaceutica Turcica

Volumn 44, Issue 2, 2002, Pages 87-96

  Arora, R ^a   Srivastava, A K ^a   Rani, M ^a   Mishra, B ^a  

^a BANARAS HINDU UNIVERSITY   (India)

Author keywords

Controlled drug delivery; Ketorolac tromethamine; NSAID; Osmotic matrix tablets

Indexed keywords

CELLULOSE ACETATE; HYDROXYPROPYLMETHYLCELLULOSE; KETOROLAC TROMETAMOL; MACROGOL 400;

ARTICLE; CONTROLLED DRUG RELEASE; MATRIX TABLET; OSMOSIS; REGRESSION ANALYSIS; SCANNING ELECTRON MICROSCOPY; TABLET FORMULATION;

EID: 0036921094     PISSN: 1300638X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Bettini, R. Catellani, P.L., Colombo, P. (1996). Osmotic matrix for controlled drug delivery Proceed Intern. Symp. Control. Rel. Bioact. Mater., Controlled Release Society, Inc., 23.
2. Catellani, P.L., Colombo, P., Peppas, N.A., Santi, P., Bettini, R. (1998). Partial permselective coating adds an osmotic contribution to drug release from swellable matrix. J. Pharm. Sci. 87:726-731.
3. Colombo, P., Bettini, R., Massimo, G., Catellani, P.L., Santi, P., Peppas, N.A. (1995). Drug diffusion front movement is important in drug release control from swellable matrix tablets. J. Pharm. Sci. 84: 991-997.
4. Colombo, P., Catellani, P.L., Maggi, L., Peppas, N.A. and Conte, U. (1992). Swelling characteristics of hydrophilic matrices for controlled release-new dimensionless to describe the swelling and release behaviour. Int. J. Pharm. 88: 99-109.
5. Danckwerts, M.P. (1994). Development of a zero-order release oral compressed tablet with potential for commercial tabletting production. Int. J. Pharm. 112: 37-45.
6. Genc, L., Guler, E., Hegazy, N. (1997). Film-coated enteric tablet formulation of ketorolac tromethanine. Drug Dev. Ind. Pharm. 23: 1007-1011.
7. Gordon, M.S., Ling, T.L., Yee, J.P. (1995). Ketorolac tromethamine bioavailability via tablet, capsule and oral solution dosage form. Drug Dev. Ind. Pharm. 21: 1143-1155.
8. Higuchi, T. (1963). Mechanism of sustained action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices. J. Pharm. Sci. 52: 1145-1149.
9. Higuchi, W.I. (1962). Analysis of data on the medicament release from ointments. J. Pharm. Sci. 51: 802-804.
10. Jensen, J.L., Appel, L.E., Clair, J.H., Zentner, G.M. (1995). Variables that affect the mechanism of drug release from osmotic pumps coated with acrylate/methacrylate copolymer latexes. J. Pharm. Sci. 84: 530-533.
11. Lee, V.H.L., Robinson, J.R. (1987). Influence of drug's properties and routes of administration on the design of sustained and controlled release systems in controlled drug delivery, in (Robinson, J.R. and Lee, V.H.L. eds.), Controlled Drug Delivery-Fundamentals and Applications; Marcel Dekker, New York, pp. 3-61.
12. Peppas, N.A., Franson, N.M. (1983). The swelling interface number as a criterion for prediction of diffusional solute release mechanisms in swellable polymers. J. Polym. Sci. 21: 983-997.
13. Ramadan, M.A., Tawashi, R. (1987). The effect of hydrodynamic conditions and delivery orifice size on the rate of drug release from the elementary osmotic pump system, Drug Dev. Ind. Pharm. 13: 235-248.
14. Sankar, C., Rani, M., Srivastava, A.K., Mishra, B. (2001). Chitosan based pentazocine microspheres for intranasal systemic delivery-development and biopharmaceutical evaluation. Pharmazie 56: 223-226.
15. Theeuwes, F. (1975). Elementary osmotic pump. J. Pharm. Sci. 64: 1987-1991
16. st Rev., United States Pharmacopoeial Convention, Inc., Rockville, pp. 1277.