Creating structural manifolds from a common precursor: Basicity gradient-driven isomerization of halopyridines

European Journal of Organic Chemistry

Volumn , Issue 24, 2002, Pages 4174-4180

  Schlosser, Manfred ^a,b   Bobbio, Carla ^a  

^a Institut de chimie moleculaire et biologique Ecole Polytechnique Federale de Lausanne   (Switzerland)

^b Institut de Mathématiques B   (Switzerland)

Author keywords

Carboxylation; Fluoropyridines; Halogen metal permutation; Hydrogen metal permutation; Molecular diversity; Nucleophilic heteroaromatic substitution

Indexed keywords

2 BROMO 5 CHLORO 3 FLUORO 4 IODOPYRIDINE; 2 BROMO 5 CHLORO 3 FLUORO 4 PYRIDINECARBOXYLIC ACID; 2 BROMO 5 CHLORO 3 FLUORO 6 IODO 4 PYRIDINECARBOXYLIC ACID; 2 BROMO 5 CHLORO 3 FLUORO 6 IODOPYRIDINE; 2 BROMO 5 CHLORO 3 FLUOROPYRIDINE; 2,5 DICHLORO 3 FLUORO 4 IODOPYRIDINE; 2,5 DICHLORO 3 FLUORO 4 PYRIDENECARBOXYLIC ACID; 2,5 DICHLORO 3 FLUORO 6 IODO 4 PYRIDINECARBOXYLIC ACID; 2,5 DICHLORO 3 FLUORO 6 IODOPYRIDINE; 2,5 DICHLORO 3 FLUOROPYRIDINE; 3 CHLORO 5 FLUORO 2 IODO 4 PYRIDINECARBOXYLIC ACID; 3 CHLORO 5 FLUORO 2 IODOPYRIDINE; 3 CHLORO 5 FLUORO 2,6 DIIODO 4 PYRIDINECARBOXYLIC ACID; 3 CHLORO 5 FLUORO 2,6 DIIODOPYRIDINE; 3 CHLORO 5 FLUORO 4 IODOPYRIDINE; 3 CHLORO 5 FLUORO 4 PYRIDINECARBOXYLIC ACID; 3 CHLORO 5 FLUOROPYRIDINE; 3,6 DICHLORO 5 FLUORO 2 PYRIDINECARBOXYLIC ACID; 5 CHLORO 2,3 DIFLUOROPYRIDINE; 5 CHLORO 3 FLUORO 2 IODO 4 PYRIDINECARBOXYLIC ACID; 5 CHLORO 3 FLUORO 2 IODOPYRIDINE; 5 CHLORO 3 FLUORO 2,4 DIIODOPYRIDINE; 5 CHLORO 3 FLUORO 2H PYRIDINONE; 6 BROMO 3 CHLORO 5 FLUORO 2 PYRIDINECARBOXYLIC ACID; AMIDE; CARBON DIOXIDE; CARBOXYLIC ACID DERIVATIVE; IODINE; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; HYDROLYSIS; ISOMERISM; PROTON TRANSPORT; SYNTHESIS;

EID: 0036919406     PISSN: 1434193X     EISSN: None     Source Type: Journal    
DOI: 10.1002/1099-0690(200212)2002:24<4174::AID-EJOC4174>3.0.CO;2-6     Document Type: Article

References (9)

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