In vitro studies of activation of phagocytic cells by bioactive peptides

Journal of Physiology and Pharmacology

Volumn 53, Issue 4 I, 2002, Pages 675-688

  Stoika, R S ^a   Lutsik, M D ^a   Barska, M L ^a   Tsyrulnyk, A A ^a   Kashchak, N I ^a  

^a INSTITUTE OF CELL BIOLOGY   (Ukraine)

Author keywords

Bradykinin amyloid peptide; Formyl chemotactic peptide; Inflammation; Macrophages; Phagocytosis; PMN cells; TGF 1

Indexed keywords

AMYLOID BETA PROTEIN; ANTIINFLAMMATORY AGENT; BRADYKININ; CHEMOTACTIC PEPTIDE; FORMYL CHEMOTACTIC PEPTIDE; FORMYLMETHIONYLLEUCYLPHENYLALANINE; FORMYLPEPTIDE; GLUCOSE; INDOMETACIN; LIPOPOLYSACCHARIDE; LYSINE AESCINATE; LYSINE DERIVATIVE; NEUTRAL RED; NITRIC OXIDE; NITRITE; SUPEROXIDE; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; WHEAT GERM AGGLUTININ;

ANIMAL CELL; CELL ACTIVATION; CELL LINE; CONCENTRATION RESPONSE; CONFERENCE PAPER; GLUCOSE UTILIZATION; HUMAN; HUMAN CELL; NITROBLUE TETRAZOLIUM TEST; NONHUMAN; PHAGOCYTE; PHAGOCYTOSIS; POLYMORPHONUCLEAR CELL; QUANTITATIVE ANALYSIS; YEAST CELL;

AMYLOID BETA-PROTEIN; ANIMALS; BRADYKININ; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MACROPHAGES; MICE; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NEUTROPHILS; PEPTIDE FRAGMENTS; PHAGOCYTES; PHAGOCYTOSIS; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; WHEAT GERM AGGLUTININS; YEASTS;

EID: 0036918351     PISSN: 08675910     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (22)

1. Silverstein SC, Greenberg S, Di Virgilio F, Steinberg TH. Phagocytosis. In Fundamental Immunology, WE Paul (ed). New York, Raven Press Ltd, 1989, pp 703-720.
2. Gallin JI. Inflammation. Ibid, pp 721-733.
3. Veremeyenko KN. Kinin System. Kiev, Zdorovya, 1977, 183 p. (in Russian)
4. Sinha S, Lieberburg J. Cellular mechanisms of β-amyloid production. Proc Natl Acad Sci USA 1999; 96: 11049-11053.
5. Tiffany HL, Lavigne MC, Cui YH, Wang JM, Leto TL, Gao JL, Murphy PM. Amyloid-beta induces chemotaxis and oxidant stress by acting at formylpeptide receptor 2, a G protein coupled receptor expressed in phagocytes and brain. J Biol Chem 2001; 276: 23645-23652.
6. Schubert D, Behl C, Lesley R, Brack A, Dargusch R, Sagara Y, Kimura H. Amyloid peptides are toxic via a common oxidative mechanism. Proc Natl Acad Sci USA 1995; 92: 1989-1993.
7. Altegen Inc. A simple ELISA test for pre-symptomatic Alzheimer's disease. Clin Lab Internal 1999; September: 1605.
8. Letterio JJ, Roberts AB. Regulation of immune responses by TGF-β. Annu Rev Biochem 1998; 16: 137-161.
9. L-lysine aescinate. Temporary Pharmacopoeia Article of Ukraine. 42Y-11/37-160-95. (in Ukrainian)
10. Stoika R, Kaslnchak N, Lutsik-Kordovsky M, Boyko M, Barska M, Tsyrulnyk A. In vitro response of phagocytic cells to immunomodulating agents. Med Sci Monit 2001; 7: 652-658.
11. Lutsik MD. New affinity sorbent for isolation of lectins and its application for purification of WGA. Ukr Biochem J 1984; 56: 432-436.
12. Ishi K, Muelhauser F, Liebl U, Picard M, Kuhl S, Penke B et al. Subacute NO generation induced by Alzheimer's β-amyloid in the living brain: Reversal by inhibition of the inducible NO synthase. FASEB J 2000; 14: 1485-1489.
13. Mills EL, Quie PG. Metabolic activity of granulocytes in phagocytosis. In Investigation of Phagocytosis in Clinics. SD Douglas, PG Quie (eds). Edinburgh, London, Melbourne, New York, Churchill Livingstone, 1981, pp. 78-91.
14. Gramenitsky EM. Supravital staining of cells and tissues. Leningrad, Medgiz, 1963, 151 p. (in Russian)
15. Bradt BM, Kolb WP, Cooper NR. Complement-dependent pro-inflammatory properties of the Alzheimer's disease β-peptide. J Exp Med 1998; 188: 431-438.
16. Bondy B, Hoffmann M, Muller-Spahn F, Witzko M, Hock C. Reduced beta-amyloid response in lymphocytes of patients with Alzheimer's disease. Pharmacopsychiatry 1995; 28: 143-146.
17. Schleef H, Stelzner A, Kunze M. Effect of colchicine and indomethacine on leukocytic phagocytosis of S. aureus and E. coli. Zentralbl Bacteriol Microbiol Hyg 1984; 257: 388-399.
18. Ribachuk O, Kalashnikov A. Clinical aspects of L-lysine aescinate application for injections. World Med 2001; 10: 271-273. (in Russian)
19. Bodmer S, Podlisny MB, Selkoe DJ, Heid I, Fontana A. Transforming growth factor-beta bound to soluble derivatives of the beta amyloid precursor protein of Alzheimer's disease. Biochem Biophys Res Commun 1990; 171: 890-897.
20. Nitsch RM, Kim C, Growdon JH. Vasopressin and bradykinin regulate secretory processing of the amyloid protein precursor of Alzheimer's disease. Neurochem Res 1998; 23: 807-814.
21. Wirth KL, Fink E, Rudolphi K, Heitsch H, Deutschlander N, Weimer G. Amyloid beta-(1-40) stimulates cyclic GMP production via release of kinins in primary cultured endothelial cells. Eur J Pharmacol 1999; 382: 27-33.
22. Marx F, Blasko I, Pavelka M, Grubeck-Loebenstein B. The possible role of the immune system in Alzheimer's disease. Exp Gerontol 1998; 33: 871-881.