Intracortical excitability is modulated by a norepinephrine-reuptake inhibitor as measured with paired-pulse transcranial magnetic stimulation

Psychopharmacology

Volumn 164, Issue 2, 2002, Pages 228-232

  Herwig, Uwe ^a   Bräuer, Kerstin ^a   Connemann, Bernhard ^a   Spitzer, Manfred ^a   Schönfeldt Lecuona, Carlos ^a  

^a UNIVERSITY OF ULM   (Germany)

Author keywords

Cortical excitability; Depression; Norepinephrine reuptake inhibition; Paired pulse transcranial magnetic stimulation; Reboxetine

Indexed keywords

NORADRENALIN; NORADRENALIN UPTAKE INHIBITOR; REBOXETINE;

ADULT; AGGRESSION; ARTICLE; COLD; CONTROLLED STUDY; DRUG EFFECT; EVOKED MUSCLE RESPONSE; FACILITATION; FATIGUE; FEMALE; HUMAN; HUMAN EXPERIMENT; INGESTION; INSOMNIA; MALE; MOTOR CORTEX; NERVOUSNESS; NEUROPHYSIOLOGY; NORMAL HUMAN; POSTSYNAPTIC INHIBITION; PRIORITY JOURNAL; REFLEX; RESTLESSNESS; SIDE EFFECT; TRANSCRANIAL MAGNETIC STIMULATION;

ADRENERGIC UPTAKE INHIBITORS; ADULT; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; ELECTROMAGNETIC FIELDS; EVOKED POTENTIALS; FEMALE; HUMANS; MALE; MORPHOLINES; MOTOR CORTEX; TIME FACTORS;

EID: 0036918257     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-002-1206-z     Document Type: Article

References (25)

1. Aston-Jones G, Rajkowski J, Cohen J (1999) Role of locus coeruleus in attention and behavioral flexibility. Biol Psychiatry 46:1309-1320
2. Daskalakis ZJ, Christensen BK, Chen R, Fitzgerald PB, Zipursky RB, Kapur S (2002) Evidence for impaired cortical inhibition in schizophrenia using transcranial magnetic stimulation. Arch Gen Psychiatry 59:347-354
3. Di Lazzaro V, Oliviero A, Profice P, Pennisi MA, Di Giovanni S, Zito G, Tonali P, Rothwell JC (2000) Muscarinic receptor blockade has differential effects on the excitability of intracortical circuits in the human motor cortex. Exp Brain Res 135:455-461
4. Fitzgerald PB, Brown TL, Daskalakis ZJ, Kulkarni J (2002) A transcranial magnetic stimulation study of inhibitory deficits in the motor cortex in patients with schizophrenia. Psychiatry Res 114:11-22
5. Greenberg BD, Ziemann U, Cora-Locatelli G, Harmon A, Murphy DL, Keel JC, Wassermann EM (2000) Altered cortical excitability in obsessive-compulsive disorder. Neurology 54:142-147
6. Ilic TV, Korchounov A, Ziemann U (2002) Complex modulation of human motor cortex excitability by the specific serotonin reuptake-inhibitor sertraline. Neurosci Lett 319:116-120
7. Kujirai T, Caramia MD, Rothwell JC, Day BL, Thompson PD, Ferbert A, Wroe S, Asselman P, Marsden CD (1993) Corticocortical inhibition in human motor cortex. J Physiol 471:501-519
8. Levitt P, Moore RY (1978) Noradrenaline neuron innervation of the neocortex in the rat. Brain Res 139:219-231
9. Maeda F, Keenan JP, Pascual-Leone A (2000) Interhemispheric asymmetry of motor cortical excitability in major depression as measured by transcranial magnetic stimulation. Br J Psychiatry 177:169-173
10. Manganotti P, Bortolomasi M, Zanette G, Pawelzik T, Giacopuzzi M, Fiaschi A (2001) Intravenous clomipramine decreases excitability of human motor cortex. A study with paired magnetic stimulation. J Neurol Sci 184:27-32
11. Nelson JC (1999) A review of the efficacy of serotonergic and noradrenergic reuptake inhibitors for treatment of major depression. Biol Psychiatry 46:1301-1308
12. Plewnia C, Bartels M, Cohen L, Gerloff C (2001a) Noradrenergic modulation of human cortex excitability by the presynaptic alpha(2)-antagonist yohimbine. Neurosci Lett 307:41-44
13. Plewnia C, Cohen L, Bartels M, Gerloff C (2001b) Human cortex excitability is modulated by central norepinephrine. World J Biol Psychiatry [Suppl] 2:240S
14. Ressler KJ, Nemeroff CB (1999) Role of norepinephrine in the pathophysiology and treatment of mood disorders. Biol Psychiatry 46:1219-1233
15. Rossini PM, Barker AT, Berardelli A, Caramia MD, Caruso G, Cracco RQ, Dimitrijevic MR, Hallett M, Katayama Y, Lucking CH et al. (1994) Non-invasive electrical and magnetic stimulation of the brain, spinal cord and roots: Basic principles and procedures for routine clinical application. Report of an IFCN committee. Electroencephalogr Clin Neurophysiol 91:79-92
16. Schwenkreis P, Witscher K, Janssen F, Addo A, Dertwinkel R, Zenz M, Malin JP, Tegenthoff M (1999) Influence of the N-methyl-d-aspartate antagonist memantine on human motor cortex excitability. Neurosci Lett 270:137-140
17. Schwenkreis P, Liepert J, Witscher K, Fischer W, Weiller C, Malin JP, Tegenthoff M (2000) Riluzole suppresses motor cortex facilitation in correlation to its plasma level. A study using transcranial magnetic stimulation. Exp Brain Res 135:293-299
18. Siepmann M, Muck-Weymann M, Joraschky P, Kirch W (2001) The effects of reboxetine on autonomic and cognitive functions in healthy volunteers. Psychopharmacology 157:202-207
19. Wassermann EM, Greenberg BD, Nguyen MB, Murphy DL (2001) Motor cortex excitability correlates with an anxiety-related personality trait. Biol Psychiatry 50:377-382
20. Werhahn KJ, Kunesch E, Noachtar S, Benecke R, Classen J (1999) Differential effects on motorcortical inhibition induced by blockade of GABA uptake in humans. J Physiol 517:591-597
21. Ziemann U (1999) Intracortical inhibition and facilitation in the conventional paired TMS paradigm. Electroencephalogr Clin Neurophysiol Suppl 51:127-136
22. Ziemann U, Lonnecker S, Paulus W (1995) Inhibition of human motor cortex by ethanol. A transcranial magnetic stimulation study. Brain 118:1437-1446
23. Ziemann U, Bruns D, Paulus W (1996a) Enhancement of human motor cortex inhibition by the dopamine receptor agonist pergolide: Evidence from transcranial magnetic stimulation. Neurosci Lett 208:187-190
24. Ziemann U, Lonnecker S, Steinhoff BJ, Paulus W (1996b) The effect of lorazepam on the motor cortical excitability in man. Exp Brain Res 109:127-135
25. Ziemann U, Lonnecker S, Steinhoff BJ, Paulus W (1996c) Effects of antiepileptic drugs on motor cortex excitability in humans: A transcranial magnetic stimulation study. Ann Neurol 40:367-378