Rapid inhibition of the contraction of rat tail artery by progesterone is mediated by inhibition of calcium currents

Journal of Pharmacy and Pharmacology

Volumn 54, Issue 12, 2002, Pages 1667-1674

  Zhang, Meili ^a   Benishin, Christina G ^a   Pang, Peter K T ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; BICUCULLINE; CALCIUM CHANNEL L TYPE; CALCIUM ION; FURA 2; POTASSIUM CHLORIDE; PROGESTERONE;

ACTION POTENTIAL; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTICLE; CALCIUM CELL LEVEL; CALCIUM CURRENT; CELL CULTURE; CELL ISOLATION; CELL MEMBRANE; CLINICAL PROTOCOL; CORRELATION ANALYSIS; DOSE RESPONSE; DOSE TIME EFFECT RELATION; DRUG EFFECT; IC 50; INCUBATION TIME; MALE; NONHUMAN; PATCH CLAMP; RAT; SMOOTH MUSCLE FIBER; TAIL ARTERY; VASCULAR SMOOTH MUSCLE;

ANIMALS; ARTERIES; BICUCULLINE; CALCIUM; CALCIUM CHANNELS, L-TYPE; CELLS, CULTURED; DEPRESSION, CHEMICAL; GABA ANTAGONISTS; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; PATCH-CLAMP TECHNIQUES; POTASSIUM CHLORIDE; PROGESTERONE; RATS; RATS, SPRAGUE-DAWLEY; TAIL; TIME FACTORS; VASCULAR RESISTANCE;

EID: 0036916820     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/002235702405     Document Type: Article

References (42)

1. Baldi, E., Luconi, M., Bonaccorssi, L., Forti, G. (1998) Nongenomic effects of progesterone on spermatozoa: Mechanisms of signal transduction and clinical implications. Frontiers Biosci. 3: D1051-D1059
2. Befort, M. A., Saade, G. R., Suresh, M., Vedernikov, Y. P. (1996) Effects of estradiol-17 beta and progesterone on isolated human omental artery from premenopausal nonpregnant women and from normotensive and preeclamptic pregnant women. Am. J. Obstet. Gynecol. 174: 246-253
3. Bielefeldt, K., Waite, L., Abboud, F. M., Conklin, J. L. (1996) Non-genomic effects of progesterone on human intestinal smooth muscle cells. Am. J. Physiol. 271: G370-G376
4. 2+ influx and the acrosome reaction in human sperm. Cell Signal. 5: 531-538
5. Blackmore, P. F. (1999) Extragenomic actions of progesterone in human sperm and progesterone metabolites in human platelets. Steroids 64: 149-156
6. Blackmore, P. F., Beebe, S. J., Danforth, D. R., Alexander, N. (1990) Progesterone and 17α-hydroxyprogesterone, novel stimulators of calcium influx in human sperm. J. Biol. Chem. 265: 1376-1380
7. 2+ entry mechanisms of coronary vasoconstriction. Arterioscler. Thromb. Vasc. Biol. 19: 1034-1040
8. Ettinger, B., Friedman, G. D., Bush, T., Queensberry, C. P. (1996) Reduced mortality associated with long-term postmenopausal estrogen therapy. Obstet. Gynecol. 87: 6-12
9. Glusa, E., Graser, T., Wagber, S., Oettel, M. (1997) Mechanisms of relaxation of rat aorta in response to progesterone and synthetic progestins. Maturitas 28: 181-191
10. 2+ indicators with greatly improved fluorescence properties. Biol. Chem. 260: 3440-3450
11. Hamill, O. P., Marty, A., Neher, E., Sakmann, B., Sigworth, F. J. (1981) Improved patch-clamp techniques for high resolution current recording from cells and cell-free membrane patches. Pflugers Arch. 39: 85-100
12. 2+ release induced by thromboxane A2 in porcine coronary artery. Circulation 91: 2619-2626
13. Henderson, B. E., Paganini-Hill, A., Ross, R. K. (1991) Decreased mortality in users of estrogen replacement therapy. Arch. Intern. Med. 151: 75-78
14. + channels in myocytes from coronary arteries. Eur. J. Pharmacol. 403: 209-219
15. 2+ in guinea-pig isolated cardiac myocytes. Br. J. Pharmacol. 106: 739-745
16. Jiang, C., Sarrel, P. M., Lindsay, D. C., Poole-Wilson, P. A., Collins, P. (1992b) Progesterone induces endothelium-independent relaxation of rabbit coronary artery in vitro. Eur. J. Pharmacol. 211: 16-17
17. Kannel, W. B., Hjortland, M. C., McNamara, P. M., Gordon, T. (1976) Menopause and risk of cardiovascular disease. Ann. Intern. Med. 85: 447-452
18. Lerner, D. J., Kannel, W. B. (1986) Patterns of coronary heart disease morbidity and mortality in the sexes: A 26-year follow-up of the Framingham population. Am. Heart J. 11: 383-390
19. 2+ sensitisation of rat smooth muscle. J. Physiol. 516: 825-834
20. McCrohon, J. A., Adams, M. R., McCredie, R. J., Robinson, J., Pike, A., Abbey, M., Keech, A. C., Celermajer, D. S. (1996) Hormone replacement therapy is associated with improved arterial physiology in healthy post-menopausal women. Clin. Endocrinol. 45: 435-441
21. Mendoza, C., Soler, A., Tesarik, J. (1995) Nongenomic steroid action: Independent targeting of a plasma membrane calcium channel and a tyrosine kinase. Biochem. Biophys. Res. Comm. 210: 518-523
22. Miller, V. M., Vanhoutte, P. M. (1991) Progesterone and modulation of endothelium-dependent responses in canine coronary arteries. Am. J. Physiol. 261: R1022-R1027
23. Minshall, R. D., Miyagawa, K., Chadwick, C. C., Novy, M. J., Hernsmeyer, K. (1998) In vitro modulation of primate coronary vascular muscle cell reactivity by ovarian steroid hormones. FASEB J. 12: 1419-1429
24. i during inhibition of coronary smooth muscle contraction by 17beta-estradiol, progesterone, and testosterone. J. Pharmacol. Exp. Ther. 291: 44-52
25. Pang, P. K. T., Yang, M. C. M., Shew, R., Tenner, T. E. (1985) The vasorelaxant action of parathyroid hormone fragments on isolated rat tail artery. Blood Vessels 22: 57-64
26. Perusquia, M., Hernandez, R., Morales, M. A., Campos, M. G., Villalon, C. M. (1996) Role of endothelium in the vasodilating effect of progestins and androgens on the rat thoracic aorta. Gen. Pharmacol. 27: 181-185
27. Perusquia, M., Hernandez, R., Montano, L. M., Villalon, C. M., Campos, M. G. (1997) Inhibitory effect of sex steroids on guinea-pig airway smooth muscle contraction. Endocrinology 118: 5-10
28. Punnonen, R. H., Jokela, H. A., Dastidar, P. S., Nevala, M., Laippala, P. J. (1995) Combined oestrogen-progestin replacement therapy prevents atherosclerosis in postmenopausal women. Maturitas 21: 179-187
29. Regensteiner, J. G., Hiatt, W. R., Byyny, R. L., Pickett, C. K., Woodward, W. D., Moore, L. G. (1991) Short-term effects of estrogen and progestin on blood pressure of normotensive post-menopausal women. J. Clin. Pharmacol. 31: 543-548
30. 2+ currents in myometrial cells from immature and nonpregnant adult rats. Am. J. Physiol. 262: C293-C301
31. Rylance, P. B., Brincat, M., Lafferty, K., De Trafford, J. C., Brincat, S., Parsons, V., Studd, J. W. W. (1985) Natural progesterone and antihypertensive action. Br. Med. J. 290: 13-14
32. 2+ in single rat hepatocytes. Biochem. J. 280: 273-276
33. Shan, J., Resnick, L. M., Lewanczuk, R. Z., Karpinski, E., Li, B., Pang, P. K. T. (1993) 1,25-dihydroxyvitamin D as a cardiovascular hormone. Am. J. Hypertens. 6: 983-988
34. Shan, J., Resnick, L. M., Liu, Q. Y., Wu, X. C., Barbagallo, M., Pang, P. K. T. (1994) Vascular effects of 17β-estradiol in male Sprague-Dawley rats. Am. J. Physiol. 266: H967-H973
35. Sheldon, J. H., Argentieri, T. M. (1995) Acute administration of 17β-estradiol inhibits calcium currents in isolated guinea pig detrusor myocytes. J. Pharmacol. Exp. Ther. 274: 723-729
36. Shi, Q. X., Roldan, E. R. (1995) Evidence that a GABAA-like receptor is involved in progesterone-induced acrosomal exocytosis in mouse spermatozoa. Biol. Reprod. 52: 373-381
37. Sitzler, G., Lenz, O., Kilter, H., La Rosee, K., Bohm, M. (1996) Investigation of the negative inotropic effects of 17 beta-oestradiol in human isolated myocardial tissues. Br. J. Pharmacol. 119: 43-48
38. Spence, K. T., Plata-Salaman, C. R., Ffrench-Mullen, J. M. (1991) The neurosteroids pregnenolone and pregnenolone-sulfate but not progesterone, block Ca2+ currents in acutely isolated hippocampal CA1 neurons. Life Sci. 49: PL235-PL239
39. Stampfer, M. J., Willet, W. C., Colditz, G. A., Rosner, B., Speizer, F. E., Hennekens, C. H. (1985) A prospective study of post-menopausal estrogen therapy and coronary heart disease. N. Engl. J. Med. 313: 1044-1049
40. Wang, G. J., Wu, X. C., Chen, C. F., Lin, L. C., Huang, Y. T., Shan, J., Pang, P. K. (1999) Vasorelaxing action of rutaecarpine: Effects of rutaecarpine on calcium channel activities in vascular endothelial and smooth muscle cells. J. Pharmacol. Exp. Ther. 289: 1237-1244
41. Wang, R., Karpinski, E., Pang, P. K. (1989) Two types of calcium channels in isolated smooth muscle cells from rat tail artery. Am. J. Physiol. 256: H1361-H1368
42. 2+ currents in A7r5 vascular smooth muscle cell line. Am. J. Physiol. 266: C975-C980