Elevated potassium concentration converts excitation mechanism from make to break

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

Volumn 2, Issue , 2002, Pages 1377-1378

  Sidorov, V Y ^a   Woods, M C ^b   Wikswo, J P ^a,b  

^a VANDERBILT UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY   (United States)

Author keywords

Cardiac; Hyperkalemia; Ischemia; Potassium; Unipolar stimulation

Indexed keywords

BIOELECTRIC POTENTIALS; CARDIOLOGY; CARDIOVASCULAR SYSTEM; CATHODES; DISEASES; FLUORESCENCE; MEDICAL IMAGING; POTASSIUM;

CATHODAL THRESHOLD; FIBRILLATION; MYOCARDIAL ESHEMIA; OPTICAL FLUORESCENCE IMAGING; POTASSIUM CONCENTRATION;

TISSUE;

EID: 0036915608     PISSN: 05891019     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (7)

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2. B. Surawicz, "The interrelationship of electrolyte abnormalities and arrhythmias," in Cardiac Arrhythmias: Their Mechanisms, Diagnosis, and Management, 3rd ed., W.J. Mandel, Ed. Philadelphia: J.B. Lippincoff Company, 1995, pp. 89-109.
3. B.J. Roth, "A mathematical model of make and break electrical stimulation of cardiac tissue by a unipolar anode or cathode," IEEE Trans. Biomed. Eng., vol. 42, pp. 1174-1184, 1995.
4. J.P. Wikswo, Jr., S.-F. Lin and R.A. Abbas, "Virtual electrodes in cardiac tissue: A common mechanism for anodal and cathodal stimulation," Biophys. J., vol. 69, pp. 2195-2210, 1995.
5. B.J. Roth, "Strength-interval curves for cardiac tissue predicted using the bidomain model," J. Cardiovasc. Electrophys, vol. 7, pp. 722-737, 1996.
6. V.P. Nikolski, A.T. Sambelashvili, and I.R. Efimov, "Mechanisms of make and break excitation revisited: paradoxical break excitation during diastolic stimulation," Am. J. Physiol. Heart Circ. Physiol., vol. 282, pp. H565-575, 2002.
7. V.P. Nikolski, A. Sambelashvili, and I.R. Efimov, "Anodal-break excitation during diastolic stimulation is explained by a half-cell potential," Ann. Biomed. Eng., vol. 29, suppl. 1, pp. S-48, 2001.