Are the new single nucleotide polymorphisms (SNPs) relevant for hypertensive populations?

Journal of Hypertension

Volumn 20, Issue 12, 2002, Pages 2335-2336

  Manunta, Paolo ^a   Bianchi, Giuseppe ^a  

^a SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADDUCIN; ALDOSTERONE ANTAGONIST; ALDOSTERONE SYNTHASE; ANGIOTENSIN I; DIPEPTIDYL CARBOXYPEPTIDASE; RENIN;

ALLELE; BLOOD PRESSURE REGULATION; ENVIRONMENTAL FACTOR; GENETIC RISK; GENETIC TRANSCRIPTION; HUMAN; HYPERTENSION; NOTE; ONCOGENE RAS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PROTEIN INTERACTION; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; SODIUM ABSORPTION;

EID: 0036914991     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004872-200212000-00005     Document Type: Note

References (16)

1. Lalouel JM, Rohrwasser A. Development of genetic hypotheses in essential hypertension. J Hum Genet 2001; 46:299-306.
2. Fuchs S, Philippe J, Germain S, Mathiu F, Jeunemaitre X, Corvol P, Pinet F. Functionality of two genes polymorphisms in the human renin gene enhancer. J Hypertens 2002; 20:2391-2397.
3. Boddi M, Poggesi L, Coppo M, Zarone N, Sacchi S, Tania C, Neri Serneri GG. Human vascular renin-angiotensin system and its functional changes in relation to different sodium intakes. Hypertension 1998; 31:836-842.
4. van der Kleij FG, de Jong PE, Henning RH, de Zeeuw D, Navis G. Enhanced responses of blood pressure, renal function, and aldosterone to angiotensin I in the DD genotype are blunted by low sodium intake. J Am Soc Nephrol 2002; 13:1025-1033.
5. Cusi D, Barlassina C, Azzani T, Casari G, Citterio L, Devoto M, et al. Polymorphisms of alpha-adducin and salt sensitivity in patients with essential hypertension. Lancet 1997; 349:1353-1357.
6. Bianchi G, Cusi D. Association and linkage analysis of alpha-adducin polymorphism: Is the glass half full or half empty? Am J Hypertens 2000; 13:739-743.
7. Barlassina C, Schork NJ, Manunta P, Citterio L, Sciarrone MT, Lanella G, et al. Synergistic effect of alpha-adducin and ACE genes in causing blood pressure changes with body sodium and volume expansion. Kidney Int 2000; 57:1083-1090
8. Staessen JA, Wang JG, Brand E, Barlassina C, Birkenhager WH, Herrmann SM, et al. Effects of three candidate genes on prevalence and incidence of hypertension in a Caucasian population. J Hypertens 2001; 19:1349-1358.
9. Balkestein FJ, Wang JG, Struijker-Boudier HA, Barlassina C, Bianchi G, Birkenhager WH, et al. Carotid and femoral intima-media thickness in relation to three candidate genes in a Caucasian population. J Hypertens 2002; 20:1551-1561.
10. Wang JG, Staessen JA, Tizzoni L, Brand E, Birkenhager WH, Fagard R, et al. Renal function in relation to three candidate genes. Am J Kidney Dis 2001; 38:1158-1168.
11. Fisher ND, Hurwitz S, Jeunemaitre X, Hopkins PN, Hollenberg NK, Williams GH. Familial aggregation of low-renin hypertension. Hypertension 2002; 39:914-918.
12. Grant FD, Romero JR, Jeunemaitre X, Hunt SC, Hopkins PN, Hollenberg NH, Williams GH. Low-renin hypertension, altered sodium homeostasis, and an alpha-adducin polymorphism. Hypertension 2002; 39:191-196.
13. Glorioso N, Filigheddu F, Cusi D, Troffa C, Conti M, Natalizio M, et al. Alpha-adducin 460 Trp allele is associated with erythrocyte Na transport rate in North Sardinian primary hypertensives. Hypertension 2002; 39:357-362.
14. Sugimoto K, Hozawa A, Katsuya T, Matsubara M, Ohkubo T, Tsuji I, et al. Alpha-adducin Gly460Trp polymorphism is associated with low renin hypertension in younger subjects in the Ohasama study. J Hypertens 2002; 20:1779-1784.
15. Psaty BM, Smith NL, Heckbert SR, Vos HL, Lemaitre RN, Reiner AP, et al. Diuretic therapy, the alpha-adducin gene variant, and the risk of myocardial infarction or stroke in persons with treated hypertension. JAMA 2002; 287:1680-1689.
16. Morrison AC, Bray MS, Folsom AR, Boerwinkle E. ADD1 460W allele associated with cardiovascular disease in hypertensive individuals. Hypertension 2002; 39:1053-1057.