Adult stem cell differentiation: What does it mean?

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

Volumn 1, Issue , 2002, Pages 741-742

  Sherley, James L ^a  

^a Massachusetts Institute of Technology   (United States)

Author keywords

Adult stem cell; Asymmetric cell kinetics; Clonal expansion; Hepatic stem cell; Liver; SACK; Somatic stem cell; Stem cell; Stem cell differentiation

Indexed keywords

BIOLOGICAL ORGANS; BIOMEDICAL ENGINEERING; DISEASES; GROWTH KINETICS; TISSUE; TRANSPLANTATION (SURGICAL); TUMORS;

ASYMMETRIC CELL KINETICS; CLONAL EXPANSION; HEPATIC STEM CELL; LIVER; STEM CELL;

CELL CULTURE;

EID: 0036912608     PISSN: 05891019     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (13)

1. M. Loeffler and C. S. Potten, "Stem cells and cellular pedigrees - a conceptual introduction," In Stem Cells. C. S. Potten, Ed. San Diego: Harcourt Brace & Co., 1997, pp. 1-28.
2. G. Matioli, H. Niewisch, and H. Vogel, "Stochastic stem cell renewal," Rev. Europ. Etudes Clin. Et Biol. XV, 20-22, 1970.
3. D. Clark and J. Frisén, "Differentiation potential of adult stem cells," Curr. Opin. Genet. & Devel. 11, 575-580, 2001.
4. J. L. Sherley, "Asymmetric cell kinetics genes: the key to expansion of adult stem cells in culture," unpublished.
5. E. Fuchs and J. A. Segre, "Stem cells: A new lease on life," Cell 100, 143-156, 2000.
6. J. L. Sherley, "Tumor suppressor genes and cell kinetics in the etiology of malignant mesothelioma," in Sourcebook of Asbestos Diseases, Vol. 21, G. A. Peters and B. J. Peters, Eds. Santa Monica: Peters and Peters, 2000, pp. 91-141.
7. L. Rambhatla, et al., "Cellular senescence: ex vivo p53-dependent asymmetric cell kinetics," J. Biomed. Biotech 1, 28-37, 2001.
8. J. R. Merok and J. L. Sherley, "Breaching the kinetic barrier to in vitro somatic stem cell propagation," J. Biomed. Biotech. 1, 25-27, 2001.
9. H.-S. Lee et al., "Clonal expansion of adult rat liver epithelial stem cells by suppression of asymmetric cell kinetics", unpublished.
10. C. E. Semino et al., "A 3-dimensional peptide hydrogel culture system for enhanced hepatic stem cell differentiation", unpublished.
11. C. E. Semino, J. R. Merok, and J. L. Sherley, unpublished data.
12. J. M. Wilson, "Vehicles for gene therapy," Nature 365, 691-692, 1993.
13. M. K. Brenner, "Gene transfer to hematopoetic cells," New Engl. J. Med. 335, 337-339, 1996.