Hydroxyapatite ceramics as a carrier of gene-transduced bone marrow cells

Journal of Orthopaedic Science

Volumn 7, Issue 6, 2002, Pages 677-682

  Akahane, Manabu ^a   Ohgushi, Hajime ^b   Kuriyama, Shigeki ^c   Akahane, Takemi ^a   Takakura, Yoshinori ^a  

^a NARA MEDICAL UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^c KAGAWA UNIVERSITY   (Japan)

Author keywords

Bone marrow cell; Carrier; Gene transfer; Hydroxyapatite

Indexed keywords

HYDROXYAPATITE; KANAMYCIN KINASE; RETROVIRUS VECTOR; ROSEOLIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CERAMICS; CONTROLLED STUDY; ENDOTHELIUM CELL; FIBROBLAST; GENETIC TRANSDUCTION; GENETIC TRANSFECTION; HISTOLOGY; LONG TERMINAL REPEAT; MALE; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOCYTE; RAT; VIRAL GENE DELIVERY SYSTEM; VIRUS RECOMBINANT;

EID: 0036911343     PISSN: 09492658     EISSN: None     Source Type: Journal    
DOI: 10.1007/s007760200120     Document Type: Article

References (30)

1. Akahane M, Ohgushi H, Yoshikawa T, et al. Osteogenic phenotype expression of allogeneic rat marrow cells in porous hydroxyapatite ceramics. J Bone Miner Res 1999;14:561-8.
2. Akahane M, Kuriyama S, Ohgushi H, et al. Enhancing and suppressing effects of dexamethasone on transgene expression in vitro. Int J Mol Med (in press).
3. Allay JA, Dennis JE, Haynesworth SE, et al. LacZ and interleukin-3 expression in vivo after retroviral transduction of marrow inarrow-derived human osteogenic mesenchymal progenitors. Hum Gene Ther 1997;8:1417-27.
4. Breitbart AS, Grande DA, Mason JM, et al. Gene-enhanced tissue engineering: Applications for bone healing using cultured periosteal cells transduced retrovirally with the BMP-7 gene. Ann Plast Surg 1999;42:488-95.
5. Cavazzana-Calvo M, Hacein-Bey S, de Staint Basile G, et al. Gene therapy of human sever combined immunodeficiency (SCID)-X1 disease. Science 2000;288:669-72.
6. Claudio PP, Howard CM, Cinti C, et al. Mutations in the retino-blastoma-related gene RB2/p130 in lung tumors and suppression of tumor growth in vivo by retrovirus-mediated gene transfer. Cancer Res 2000;60:372-82.
7. Ghivizzani SC, Oligino TJ, Glorioso JC, et al. Gene therapy approaches for treating rheumatoid arthritis. Clin Orthop 2000;379:S288-99.
8. Goshima J, Goldberg VM, Caplan AI. The origin of bone formed in composite grafts of porous calcium phosphate ceramic loaded with marrow cells. Clin Orthop 1991;269:274-83.
9. Isogai N, Landis W, Kim TH, et al. Formation of phalanges and small joints by tissue-engineering. J Bone Joint Surg Am 1999;81:306-16.
10. Kocher AA, Schuster MD, Szabolcs MJ, et al. Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function. Nat Med 2001;7:430-6.
11. Kotani H, Newton PB III, Zhang S, et al. Improved methods of retroviral vector transduction and production for gene therapy. Hum Gene Ther 1994;5:19-28.
12. Kuriyama S, Yoshikawa M, Ishizaka S, et al. A potential approach for gene therapy targeting hepatoma using a liver-specific promoter on a retroviral vector. Cell Struct Funct 1991;16:503-10.
13. Kuriyama S, Nakatani T, Masui K, et al. Bystander effect caused by suicide gene expression indicates the feasibility of gene therapy for hepatocellular carcinoma. Hepatology 1995;22:1838-46.
14. Kuriyama S, Masui K, Kikukawa M, et al. Complete cure of established murine hepatocellular carcinoma is achievable by repeated injections of retroviruses carrying the herpes simplex virus thymidine kinase gene. Gene Ther 1999;6:525-33.
15. Lieberman JR, Le LQ, Wu L, et al. Regional gene therapy with a BMP-2-producing murine stromal cell line induces heterotopic and orthotopic bone formation in rodents. J Orthop Res 1998;16:330-9.
16. Maniatopoulos C, Sodek J, Melcher AH. Bone formation in vitro by stromal cells obtained from bone marrow of young adult rats. Cell Tissue Res 1988;254:317-30.
17. Musgrave DS, Bosch P, Ghivizzani S, et al. Adenovirus-mediated direct gene therapy with bone morphogenetic protein-2 produces bone. Bone 1999;24:541-7.
18. Niyibizi C, Smith P, Mi Z, et al. Potential of gene therapy for treating osteogenesis imperfecta. Clin Orthop 2000; 379(suppl)S126-33.
19. Ohgushi H, Goldberg VM, Caplan AI. Heterotopic osteogenesis in porous ceramics induced by marrow cells. J Orthop Res 1989;7:568-78.
20. Ohgushi H, Dohi Y, Katuda T, et al. In vitro bone formation by rat marrow cell culture. J Biomed Mater Res 1996;32:333-40.
21. Ohgushi H, Caplan AI. Stem cell technology and bioceramics: From cell to gene engineering. J Biomed Mater Res 1999;48:913- 27.
22. Oyama M, Tatlock A, Fukuta S, et al. Retrovirally transduced bone marrow stromal cells isolated from a mouse model of human osteogenesis imperfecta (oim) persist in bone and retain the ability to form cartilage and bone after extended passging. Gene Ther 1999;6:321-9.
23. Reyes M, Dudek A, Jahagirdar B, et al. Origin of endothelial progenitors in human postnatal bone marrow. J Clin Invest 2002;109:337-46.
24. Roth JA, Swisher SG, Merritt JA, et al. Gene therapy for non-small cell lung cancer: A preliminary report of a phase I trial of adenoviral p53 gene replacement. Semin Oncol 1998;25:33-7.
25. Skotzko M, Wu L, Anderson WF, et al. Retroviral vector-mediated gene transfer of antisense cyclin G1 (CYCG1) inhibits proliferation of human osteogenic sarcoma cells. Cancer Res 1995;55:5493-8.
26. Swisher SG, Roth JA, Nemunaitis J, et al. Adenovirus-mediated p53 gene transfer in advanced non-small-cell lung cancer. J Natl Cancer Inst 1999;91:763-71.
27. Yoshikawa T, Ohgushi H, Tamai S. Immediate bone forming capability of prefabricated osteogenic hydroxyapatite. J Biomed Mater Res 1996;32:481-92.
28. Yoshikawa T, Ohgushi H, Akahane M, et al. Analysis of gene expression in osteogenic cultured marrow/hydroxyapatite construct implanted at ectopic sites: A comparison with the osteogenic ability of cancellous bone. J Biomed Mater Res 1998;41:568-73.
29. Yoshikawa T, Ohgushi H, Nakajima H, et al. In vivo osteogenic durability of cultured bone in porous ceramics: A novel method for autogenous bone graft substitution. Transplantation 2000;69:128- 34.
30. Yoshimatsu T, Tamura M, Kuriyama S, et al. Improvement of retroviral packaging cell lines by introducing the polyomavirus early region. Hum Gene Ther 1998;9:161-72.