Effects of an eosinophil chemotaxis inhibitor, TAK-661, on antigen-induced asthmatic responses in allergic sheep

Lung

Volumn 180, Issue 3, 2002, Pages 161-172

  Fujimoto, Keisaku ^a   Tsunoda, T ^a   Koizumi, T ^a   Kubo, K ^a  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Airway hyperresponsiveness; Bronchial asthma; Eosinophil chemotaxis; Late asthmatic response (LAR); Sheep

Indexed keywords

ANTIGEN; BUFFER; CHEMOTAXIS INHIBITOR; PHOSPHATE; PLACEBO; SODIUM CHLORIDE; TAK 661;

ALLERGY; ANIMAL MODEL; ARTICLE; ASCARIS SUUM; ASTHMA; BIOACCUMULATION; BRONCHOSPASM; CELL INFILTRATION; CONTROLLED STUDY; DRUG EFFECT; EOSINOPHIL; HISTOLOGY; HUMAN; INFLAMMATION; LUNG LAVAGE; LUNG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; REDUCTION; SHEEP;

ANIMALS; ANTIGENS; ASTHMA; BRONCHOCONSTRICTION; CELL MOVEMENT; CHEMOTACTIC FACTORS, EOSINOPHIL; DISEASE MODELS, ANIMAL; DRUG EVALUATION; EOSINOPHILS; RESPIRATORY HYPERSENSITIVITY; SHEEP; TIME FACTORS; TREATMENT OUTCOME;

EID: 0036904144     PISSN: 03412040     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004080000090     Document Type: Article

References (28)

1. Aalbers R, De Monchy JGR, Kauffman HF, Smith M, Hoekstra Y, Vrugt B, Timens W (1993) Dynamics of eosinophil infiltration in the bronchial mucosa before and after the late asthmatic reaction. Eur Respir J 6:840-847
2. Abraham WM (1997) Sheep models of allergic bronchoconstriction. In: Kay AB (ed) Allergy and Allergic Disease, vol 2. Blackwell Science, Oxford, pp 1037-1044
3. Akutsu I, Kojima T, Kariyone A, Fukuda T, Makino S, Takatsu K (1995) Antibody against interleukin-5 prevents antigen-induced eosinophil infiltration and bronchial hyperreactivity in the guinea pig airways. Immunol Lett 45:109-116
4. Bentley AM, Menz G, Storz CHR, Robinson DS, Bradley B, Jeffery PK, Durham SR, Kay AB (1992) Identification of T lymphocytes, macrophages, and activated eosinophils in the bronchial mucosa in intrinsic asthma. Am Rev Respir Dis 146:500-506
5. Bousquet J, Chanez P, Lacoste JY, Barneon G, Ghavanian N, Enander I, Venge P, Ahlstedt S, Simony-Lafontaine J, Godard P, Michel FB (1990) Eosinophilic inflammation in asthma. N Engl J Med 323:1033-1039
6. Bousquet J, Chanez P, Vignola AM, Lacoste JY, Michel FB (1994) Eosinophil inflammation in asthma. Am J Respir Crit Care Med 150:S33-S38
7. Brown JR, Kleimberg J, Marini M, Sun G, Bellini A, Mattoli S (1998) Kinetics of eotaxin expression and its relationship to eosinophil accumulation and activation in bronchial biopsies and bronchoalveolar lavage (BAL) of asthmatic patients after allergen inhalation. Clin Exp Immunol 114:137-146
8. De Monchy JGR, Kauffman HF, Venge P, Koeter GH, Jansen HM, Sluiter H J, De Vries K (1985) Bronchoalveolar eosinophilia during allergen-induced late asthmatic reactions. Am Rev Respir Dis 131:373-378
9. Durham SR, Kay AB (1985) Eosinophils, bronchial hyperreactivity and late-phase asthmatic reactions. Clin Allergy 15:411-418
10. Fujimoto K, Kubo K, Shinozaki S, Okada K, Matsuzawa Y, Kobayashi T, Sugane K (1995) Neutrophil elastase inhibitor reduces asthmatic responses in allergic sheep. Respir Physiol 100:91-100
11. Fujimoto K, Kubo K, Okada K, Kobayashi T, Sekiguchi M, Sakai A (1996) Effect of the 21-aminosteroid U-74006F on antigen-induced bronchoconstriction and bronchoalveolar eosinophilia in allergic sheep. Eur Respir J 9:2044-2049
12. Fujimoto K, Kubo K, Matsuzawa Y, Sekiguchi M (1997) Eosinophil cationic protein levels in induced sputum correlate with the severity of bronchial asthma. Chest 112:1241-1247
13. Fujisawa M, Matsumoto T, Yamasaki M, Kawano Y, Ashida Y (1999) Effect of eosinophil chemotaxis inhibitor TAK-661 on antigen-induced immediate and late airway responses, lung eosinophilia, and airway hyperresponsiveness in guinea pigs. Am J Respir Crit Care Med 159:A114
14. Graziano FM, Cook EB, Stahl JL (1999) Cytokines, chemokines, RANTES, and eotaxin. Allergy Asthma Proc 20:141-146
15. Jeffery PK (1994) Comparative morphology of the airways in asthma and chronic obstructive pulmonary disease. Am Rev Respir Crit Care Med 150:S6-13
16. Kraneveld AD, Folkerts G, Van Oosterhout AJM, Nijkamp F (1997) Airway hyperresponsiveness: First eosinophils and then neuropeptides. Int J Immunopharmacol 19:517-527
17. Leckie MJ, Brinke A, Khan J, Diamant Z, O'Connor BJ, Walls CM, Mathur AK, Cowley HC, Chung KF, Djukanovic R, Hansel TT, Holgate ST, Sterk P J, Barnes PJ (2000) Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response. Lancet 356:2144-2148
18. Mauser PJ, Pitman A, Witt A, Fernandez X, Zurcher J, Kung T, Jones H, Watnick AS, Egan RW, Kreutner W, Adams GK (1993) Inhibitory effect of the TRFK-5 anti-IL-5 antibody in a guinea pig model of asthma. Am Rev Respir Dis 148:1623-1627
19. Meltzer S, Goldberg B, Lad P, Easton J (1989) Superoxide generation and its modulation by adenosine in the neutrophils of subjects with asthma. J Allergy Clin Immunol 83:960-966
20. O'Byrne PM, Israel E, Drazen JM (1997) Anti-leukotrienes in the treatment of asthma. Ann Int Med 127:472-480
21. Pretolani M, Ruffle C, Joseph D, Campos MG, Church MK, Lefort J, Vargaftig BB (1994) Role of eosinophil activation in the bronchial reactivity of allergic guinea pigs. Am J Respir Crit Care Med 149:1167-1174
22. Redington AE, Howarth PH (1997) Airway wall remodeling in asthma. Thorax 52:310-312
23. Sadeghi Hashjin G, Folkerts G, Henricks PA, Verheyen AK, van der Linde H J, van Ark I, Coene A, Nijkamp FP (1996) Peroxynitrite induces airway hyperresponsiveness in guinea pigs in vitro and in vivo. Am J Respir Crit Care Med 153:1697-1701
24. Soler M, Sielczak M, Abraham WM (1991) Separation of late bronchial responses from airway hyperresponsiveness in allergic sheep. J Appl Physiol 70:617-623
25. Taylor IK, O'Shaughnessy KM, Fuller R, Dollery CT (1991) Effect of cysteinyl-leukotriene receptor antagonist ICI 204, 219 on allergen-induced bronchoconstriction and airway hyperreactivity in atopic subjects. Lancet 337:690-694
26. Van Oosterhout AJM, Fattah D, Van Ark I, Hofman G, Buckley TL, Nijkamp FP (1995) Eosinophil infiltration precedes development of airway hyperreactivity and mucosal exudation after intranasal administration of interleukin-5 to mice. J Allergy Clin Immunol 96:104-112
27. Virchow JC, Holscher U, Virchow C (1992) Sputum ECP levels correlate with parameters of airflow obstruction. Am Rev Respir Dis 146:604-606
28. Wegner CD, Gundel RH, Reilly P, Haynes N, Letts LG, Rothlein R (1990) Intercellular adhesion molecule-1 (ICAM-1) in the pathogenesis of asthma. Science 247:456-59