Expression of vascular endothelial growth factor and its receptors KDR and Flt-1 in gastric cancer cells

World Journal of Gastroenterology

Volumn 8, Issue 6, 2002, Pages 994-998

  Zhang, Hua ^a   Wu, Jian ^a   Meng, Lin ^a   Shou, Cheng Chao ^a  

^a PEKING UNIVERSITY CANCER HOSPITAL AND INSTITUTE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

ARTICLE; ASSAY; AUTOCRINE EFFECT; CANCER CELL; CANCER CELL CULTURE; CANCER GROWTH; CELL PROLIFERATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; METASTASIS; MOLECULAR MECHANICS; NEWBORN; NUCLEOTIDE SEQUENCE; PARACRINE SIGNALING; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH CANCER; STOMACH CARCINOMA; TUMOR GROWTH;

EID: 0036899493     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v8.i6.994     Document Type: Article

References (37)

1. Song ZJ, Gong P, Wu YE. Relationship between the expression of iNOS, VEGF, tumor angiogenesis and gastric cancer. World J Gastroenterol 2002; 8: 591-595
2. Mao H, Yuan AL, Zhao MF, Lai ZS, Zhang YL, Zhou DY. Effect of p38MAPK signal pathway on ultrastructural change of liver cancer cells induced by VEGF. Shijie Huaren Xiaohua Zazhi 2000; 8: 536-538
3. Qin LX, Tang ZY. The prognostic molecular markers in hepatocellular carcinoma. World J Gastroenterol 2002; 8: 385-392
4. 121 in gastric carcinoma MGC803 cell line. World J Gastroenterol 2000; 6: 281-283
5. Yan JC, Chen WB, Ma Y, Shun XH. Expression of vascular endothelial growth factor in liver tissues of hepatitis B. Shijie Huaren Xiaohua Zazhi 1999; 7: 837-840
6. Zhao MF, Mao H, Zheng JX, Yuan YW. Effect of vascular endothelial growth factor on adhesion of large intestine cancer cell HT-29. Shijie Huaren Xiaohua Zazhi 2000; 8: 646-649
7. Tang YC, Li Y, Qian GX. Reduction of tumorigenicity of SMMC-7721 hepatoma cells by vascular endothelial growth factor antisense gene therapy. World J Gastroenterol 2001; 7: 22-27
8. Gu ZP, Wang YJ, Li JG, Zhou YA. VEGF165 antisense RNA suppresses oncogenic properties of human esophageal squamous cell carcinoma. World J Gastroenterol 2002; 8: 44-48
9. Soker S, Takashima S, Miao HQ, Neufeld G, Klagsbrun M. Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell 1998; 92: 735-745
10. Griffioen AW, Molema G. Angiogenesis: Potentials for pharmacologic intervention in the treatment of cancer, cardiovascular diseases, and chronic inflammation. Pharmacol Rev 2000; 52: 237P-268
11. Bellamy WT, Richter L, Frutiger Y, Grogan TM. Expression of vascular endothelial growth factor and its receptors in hematopoietic malignancies. Cancer Res 1999; 59: 728-733
12. Dias S, Hattori K, Zhu ZP, Heissig B, Choy M, Lane W, Wu Y, Chadburn A, Hyjek E, Gill M, Hicklin DJ, Witte L, Moore M.A.S. Raffi S. Autocrine stimulation of VEGFR-2 activates human leukemic cell growth and migration. J Clin Invest 106: 511-521
13. Dias S, Hattori K, Heissig B, Zhu ZP, Wu Y, Witte L, Hicklin DJ, Tateno M, Bohlen P, Moore M.A.S., Rafii S. Inhibition of both paracrine and autocrine VEGF/VEGFR-2 signaling pathways is essential to induce long-term remission of xenotransplanted human leukemias. Proc Natl Acad Sci USA 2001; 98: 10857-10862
14. Hayashibara T, Yamada Y, Miyanishi T, Mori H, Joh T, Maeda T, Mori N, Maita T, Kamihira S, Tomonaga M. Vascular endothelial growth factor and cellular chemotaxis: A possible autocrine pathway in adult T-cell leukemia cell invasion. Clin Cancer Res 2001; 7: 2719-2726
15. Marschall ZV, Cramer T, Hocker M, Burde R, Plath T, Schirner M, Heidenreich R, Breier G, Riecken EO, Wiedenmann B, Rosewicz S. De novo expression of vascular endothelial growth factor in human pancreatic cancer: Evidence for an autocrine mitogenic loop. Gastroenterology 2000; 119: 1358-1372
16. De Jong JS, Van Diest PJ, Van Der Valk P, Baak JPA. Expression of growth factors, growth inhibiting factors, and their receptors in invasion breast cancer. I: An inventory in search of autocrine and paracrine loops. J Pathol 1998; 184: 44-52
17. Meister B, Grunebach F, Bautz F, Brugger W, Fink F-M, Kanz L, Mohle R. Expression of vascular endothelial growth factor(VEGF) and its receptor in human neuroblastoma. Eur J Cancer 1999; 35: 445-449
18. Masood R, Cai J, Zheng T, Smith DL, Hinton DR, Gill PS. Vascular endothelial growth factor(VEGF) is an autocrine growth factor for VEGF receptor-positive human tumors. Blood 2001; 98: 1904-1913
19. Takahama M, Tsutsumi M, Tsujiuchi T, Kido A, Sakitani H, Iki K, Taniguchi S, Kitamura S, Konishi Y. Expression of vascular endothelial growth factor and its receptors during lung carcinogenesis by N-nitrosobis(2-hydroxypropyl)amine in rats. Mol Carcinog 1999; 24: 287-293
20. Tian X, Song S, Wu J, Meng L, Dong Z, Shou C. Vascular endothelial growth factor: Acting as an autocrine growth factor for human gastric adenocarcinoma cell MGC803. Biochem Biophys Res Commun 2001; 286: 505-512
21. Wang H, Keiser JA. Vascular endothelial growth factor upregulates the expression of matrix metalloproteinases in vascular smooth muscle cells: Role of flt-1. Circ Res 1998; 83: 832-840
22. Cai L, Yu SZ. A molecular epidemiologic study on gastric cancer in Changle, Fujian Province. Shijie Huaren Xiaohua Zazhi 1999; 7: 652-655
23. Wong BC, Lam SK, Ching CK, Hu WH, Kwok E, Ho J, Yuen ST, Gao Z, Chen JS, Lai KC, Ong LY, Chen BW, Wang WH, Jiang XW, Hou XH, Lu JY. Differential Helicobacter pylori infection rates in two contrasting gastric cancer risk regions of South China. China Gastric Cancer Study Group. J Gastroenterol Hepatol 1999; 14: 120-125
24. Gao GL, Yang Y, Yang SF, Ren CW. Relationship between proliferation of vascular endothelial cells and gastric cancer. Shijie Huaren Xiaohua Zazhi 2000; 8: 282-284
25. Zou SC, Qiu HS, Zhang CW, Tao HQ. A clinical and long term follow up study of peri operative sequential triple therapy for gastric cancer. World J Gastroenterol 2000; 6: 284-286
26. Zhang XQ, Lin SR. The study advance of Helicobacter pylori and gastric cancer. Shijie Huaren Xiaohua Zazhi 2000; 8: 206-207
27. Xue XC, Fang GE, Hua JD. Gastric cancer and apoptosis. Shijie Huaren Xiaohua Zazhi 1999; 7: 359-361
28. Cai L, Yu SZ, Zhang ZF. Helicobacter pylori infection and risk of gastric cancer in Changle Country, Fujian Province, China. World J Gastroenterol 2000; 6: 374-376
29. Harrg XH. Association between Helicobacter pylori and gastric cancer: Current knowledge and future research. World J Gastroenterol 1998;4: 93-96
30. Folli S, Morgagni P, Roviello F, De Manzoni G, Marrelli D, Saragoni L, Di Leo A, Gaudio M, Nanni O, Carli A, Cordiano C, Dell'Amore D, Vio A. Risk factors for lymph node metastases and their prognostic significance in early gastric cancer (EGC) for the Italian Research Group for Gastric Cancer (IRGGC). Jpn J Clin Oncol 2001; 31: 495-499
31. Yokota T, Kunii Y, Teshima S, Yamada Y, Saito T, Takahashi M, Kikuchi S, Yamauchi H. Significant prognostic factors in patients with early gastric cancer. Int Surg 2000; 85: 286-290
32. Kocher HM, Linklater K, Patel S, Ellul JP. Epidemiological study of oesophageal and gastric cancer in south-east England. Br J Surg 2001; 88: 1249-1257
33. Barchielli A, Amorosi A, Balzi D, Crocetti E, Nesi G. Long-term prognosis of gastric cancer in a European Country: A population-based study in Florence (Italy). 10-year survival of cases diagnosed in 1985-1987. Eur J Cancer 2001; 37: 1674-1680
34. Xu CT, Huang LT, Pan BR. Current gene therapy for stomach carcinoma. World J Gastroenterol 2001; 7: 752-759
35. Niu WX, Qin XY, Liu H, Wang CP. Clinicopathological analysis of patients with gastric cancer in 1200 cases. World J Gastroenterol 2001; 7: 281-284
36. Li XY, Wei PK. Diagnosis of stomach cancer by serum tumor markers. Shijie Huaren Xiaohua Zazhi 2001; 9: 568-570
37. Er Z. Aibian Jili Yanjiou. Beijing: Beijing Press, 1999: 447-449