Aging in bacteria

Current Opinion in Microbiology

Volumn 5, Issue 6, 2002, Pages 596-601

  Nyström, Thomas ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; REACTIVE OXYGEN METABOLITE; RNA POLYMERASE; SIGMA FACTOR;

BACTERIAL CELL; BACTERIAL GENE; BACTERIAL GENETICS; BACTERIAL REPRODUCTION; BACTERIAL SURVIVAL; CALORIC RESTRICTION; CELL AGING; CELL DIVISION; CYTOKINESIS; ESCHERICHIA COLI; GENE EXPRESSION; MOLECULAR MODEL; NONHUMAN; OXIDATION; PLEIOTROPY; REVIEW; RNA TRANSLATION;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0036898921     PISSN: 13695274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1369-5274(02)00367-3     Document Type: Review

References (44)

1. Hayflick L: The limited in vitro lifetime of human diploid cell strains. Exp Cell Res 1965, 37:614-636.
2. Williams GC: Pleiotropy, natural selection, and the evolution of senescence. Evolution 1957, 11:398-411.
3. Ericsson M, Hanstorp D, Hagberg P, Enger J, Nyström T: Sorting out bacterial viability with optical tweezers. J Bacteriol 2000, 182:5551-5555. This paper reports on the use of laser tweezers and microchambers to evaluate bacterial viability by two independent measurements: Cell membrane integrity and reproductive ability. It is shown that, contrary to previous belief, a stationary-phase E, coli population does not harbor a large fraction of intact but non-culturable cells.
4. Nyström T: Starvation, cessation of growth and bacterial aging. Curr Opin Microbiol 1999, 2:214-219.
5. Matin A: The molecular basis of carbon-starvation-induced general resistance in Escherichia coli. Mol Microbiol 1991, 5:3-10.
6. Hengge-Aronis R: The general stress response in Escherichia coli. In Bacterial Stress Responses. Edited by Storz G, Hengge-Aronis R. Washington DC: American Society of Microbiology Press; 2000:161-179.
7. Nyström T: Not quite dead enough. Arch Microbiol 2001, 176:159-164.
8. Larsen PL: Aging and resistance to oxidative damage in Caenorhabditis elegans. Proc Natl Acad Sci USA 1993, 90:8905-8909.
9. Johnson TE, Cypser J, de Castro E, de Castro S, Henderson S, Murakami S, Rikke B, Tedesco P, Link C: Gerontogenes mediate health and longevity in nematodes through increasing resistance to environmental toxins and stressors. Exp Gerontol 2000, 35:687-694.
10. Yasuda K, Adachi H, Fujiwara Y, Ishii N: Protein carbonyl accumulation in aging dauer formation-defective (daf) mutants of Caenorhabditis elegans. J Gerontol 1999, 54:47-51.
11. Dukan S, Nyström T: Bacterial senescence: Stasis results in increased and differential oxidation of cytoplasmic proteins leading to developmental induction of the heat shock regulon. Genes Dev 1998, 12:3431-3441.
12. Dukan S, Nyström T: Oxidative stress defence and deterioration of growth-arrested Escherichia coli cells. J Biol Chem 1999, 274:26027-26032.
13. Vlamis-Gardikas A, Potamitou A, Zarivach R, Hochman A, Holmgren A: Characterization of Escherichia coli null mutants for glutaredoxin 2. J Biol Chem 2002, 277:10861-10868.
14. S regulons during stasis is intimately connected to free radical defence.
15. S).
16. Kurland CG, Mikkola R: The impact of nutritional state on the microevolution of ribosomes. In Starvation in Bacteria. Edited by Kjelleberg S. New York: Plenum Press; 1993:225-238.
17. Farewell A, Kvint K, Nyström T: Negative regulation by RpoS: A case of sigma factor competition. Mol Microbiol 1998, 29:1039-1052.
18. 70 by shifting the relative competitiveness of the sigma factors.
19. 54-dependent Po promoter. Mol Microbiol 1999, 31:1217-1228.
20. Carmona M, Rodriguez MJ, Martinez-Costa O, De Lorenzo V: In vivo and in vitro effects of (p)ppGpp on the sigma(54) promoter Pu of the TOL plasmid of Pseudomonas putida. J Bacteriol 2000, 182:4711-4718.
21. Grossman AD, Taylor WE, Burton ZF, Burgess RR, Gross CA: Stringent response in Escherichia coli induces expression of heat shock proteins. J Mol Biol 1985, 186:357-365.
22. VanBogelen RA, Neidhardt FC: Ribosomes as sensors of heat and cold shock in Escherichia coli. Proc Natl Acad Sci USA 1990, 87:5589-5593.
23. S is positively regulated by ppGpp. J Bacteriol 1993, 175:7982-7989.
24. S subunit of RNA polymerase in Escherichia coli. J Bacteriol 1995, 177:4676-4680.
25. S level in starving Escherichia coli cells increases solely as a result of its increased stability, despite decreased synthesis. Mol Microbiol 1997, 24:643-651.
26. S. It is suggested that ppGpp exerts a dual control on the RpoS regulon by affecting both the production of the required sigma factor and its activity.
27. Kirkwood TB: Evolution of ageing. Nature 1977, 24:301-304.
28. Chen JB, Sun J, Jazwinski SM: Prolongation of life span by the v-Ha-RAS oncogene. Mol Microbiol 1990, 4:2081-2086.
29. Marchler G, Schuller C, Adam G, Ruis HA: A Saccharomyces cerevisiae UAS element controlled by protein kinase A activates transcription in response to a variety of stress conditions. EMBO J 1993, 12:1997-2003.
30. Martinez-Pastor MT, Marchler GSC, Marchler-Bauer A, Ruis H, Estruc F: The Saccharomyces cerevisiae zinc finger proteins Msn2p and Msn4p are required for transcriptional induction through the stress-response element (STRE). EMBO J 1996, 15:2227-2235.
31. Ueguchi C, Misonou N, Mizuno T: Negative control of rpoS expression by phosphoenolpyruvate: Carbohydrate phosphotransferase system in Escherichia coli. J Bacteriol 2001, 183:520-527. A series of genetic analyses reveals that Crr negatively controls rpoS translation and transcription. It is argued that, whereas the observed transcriptional control by Crr appears to be mediated by cyclic AMP, the negative control of rpoS translation is governed by a more direct Crr-dependent mechanism.
32. Orr WC, Sohal RS: Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster. Science 1994, 263:1128-1130.
33. Parkes TL, Ella AJ, Dickinson D, Hilliker AJ, Phillips JP, Boulianne GL: Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons. Nat Genet 1998, 19:171-174.
34. Sun J, Folk D, Bradley TJ, Tower J: Induced overexpression of mitochondrial Mn-superoxide dismutase extends the life span of adult Drosophila melanogaster. Genetics 2002, 161:661-672.
35. Ballesteros M, Fredriksson Å, Henriksson J, Nyström T: Bacterial senescence: Protein oxidation in non-proliferating cells is dictated by the accuracy of the ribosomes. EMBO J 2001, 18:5280-5289. Using a proteomic/immunochemical approach to analyse protein oxidation, the authors of this paper demonstrate that the increased oxidation of proteins in growth-arrested cells is intimately linked to the production of aberrant protein isoforms. Stasis-induced oxidation is drastically attenuated in mutants with hyperaccurate ribosomes, whereas oxidation is enhanced in mutants with error-prone ribosomes. The data point to alternative ways of approaching oxidation in growth-arrested and aging cells.
36. O cells. Instead, it is shown that increased oxidation of target proteins occurs during a state transition in the respiratory apparatus and that this oxidation can be mitigated by blocking the quinones in the reduced form by Myxothiazol.
37. O'Farrell PH: The suppression of defective translation by ppGpp and its role in the stringent response. Cell 1978, 14:545-557.
38. Dukan S, Farewell A, Ballestreros M, Taddei F, Radman M, Nyström T: Proteins are oxidatively carbonylated in response to reduced transcriptional or translational fidelity. Proc Natl Acad Sci USA 2000, 97:5746-5749. Several different means of increasing error rates in protein biosynthesis is reported to cause an increase in total protein oxidation without an apparent increase in reactive oxygen species (ROS) production or a decrease in ROS defences. The use of diagnostic proteomics demonstrated that protein oxidation is strongly associated to the production of aberrant protein isoforms. The authors of this paper hypothesize that oxidation of proteins occurs in the absence of increased oxidative stress, elevated levels of ROS, or a diminished defence system, but may instead be due to increased concentration of substrates (misfolded proteins) available for oxidative attack.
39. Wenthzel AM, Stancek M, Isaksson LA: Growth phase dependent stop codon readthrough and shift of translation reading frame in Escherichia coli. FEBS Lett 1998, 421:237-242.
40. Barak Z, Gallant J, Lindsley D, Kwieciszewki B, Heidel D: Enhanced ribosome frameshifting in stationary phase cells. J Mol Biol 1996, 263:140-148.
41. Orgel LE: The maintenance of the accuracy of protein synthesis and its relevance to ageing. Proc Natl Acad Sci USA 1963, 49:517-521.
42. Kowald A, Kirkwood TB: Towards a network theory of ageing: A model combining the free radical theory and the protein error theory. J Theor Biol 1994, 21:493-508.
43. Gallant J, Kurland C, Parker J, Holliday R, Rosenberger R: The error catastrophe theory of aging: Point Counterpoint. Exp Gerontol 1997, 32:333-346.
44. Starke PE, Oliver CN, Stadtman ER: Modification of hepatic proteins in rats exposed to high oxygen concentration. FASEB J 1987, 1:36-39.